The drive from Amory, MS to Clinton, MS covers 188.7 miles and takes about 4h 3m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on MS 25, US Highway 45 Alternate, Highway 125 for much of the mileage,
and the overall profile is highway-focused drive.
The longest uninterrupted segment is about 152.9 miles on MS 25.
At current regular gas prices, budget about $28.74 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
94.3 miles from Amory, MS
A natural place for your longest stop of the day
, about 2h 5m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 4h 3m. Total distance: 188.7 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
4h 3m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (94%). Some complex stretches to watch for.
Drive Character
This is a 4h 3m highway drive covering 188.7 miles, with most of the trip on MS 25 and US Highway 45 Alternate. The longest continuous stretch is about 152.9 miles on MS 25.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 26 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
MS 25 is the longest continuous segment at about 152.9 miles.
How Hard Is This Drive?
This is a straightforward highway drive that stays mostly on MS 25 and US Highway 45 Alternate. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.4 miles in near US 278 / 6th Avenue South.
Driving Effort8/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 19 significant decision points across 188.7 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 0.4 miles (US 278 / 6th Avenue South): Lane positioning matters here; at 0.7 miles (Highway 125): Lane positioning matters here; at 5.9 miles (MS 25): Navigation decision point.
Critical Maneuvers
5 of 19 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
6
0.4 mi into trip|~0m in|US 278 / 6th Avenue South
Turn right onto US 278 / 6th Avenue South
Lane positioning matters here
Use the straight / right lanes.
5
0.7 mi into trip|~1m in|Highway 125
Turn left onto Highway 125
Lane positioning matters here
Use the left lane.
5
5.9 mi into trip|~10m in|MS 25
At end of road, turn right onto MS 25
Navigation decision point
8
12.4 mi into trip|~20m in|MS 8; MS 25
Keep slight right at fork onto MS 8; MS 25 toward US 45 North, MS 25 South, MS 8 West: Tupelo, Aberdeen
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / right lanes.
Toward US 45 North, MS 25 South, MS 8 West: Tup...
6
188.6 mi into trip|~4h 3m in|Dunton Road
At end of road, turn left onto Dunton Road
Complex interchange - multiple decisions in a short stretch
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Amory, MS to Clinton, MS, road signs begin pointing toward Aberdeen along the way.
Aberdeen
12.4 mi in|~20m|via MS 8; MS 25
Main Roads
Road
Distance
Duration
MS 25
152.9 mi
3h 4m
US Highway 45 Alternate
15.5 mi
20m
Highway 125
5.2 mi
9m
MS 8
4.6 mi
7m
Clinton Boulevard
4 mi
7m
East Woodrow Wilson Avenue
2.9 mi
5m
Bullard Street
1.3 mi
2m
Oakwood Drive
0.5 mi
1m
Longest stretch:
MS 25
— 152.9 mi, about 3h 4m
Turn-by-Turn Driving Directions
Step-by-step road directions between Amory, MS and Clinton, MS.
1
Start on 2nd Avenue South
47 ft·7 sec·2nd Avenue South
2
Turn left onto MS 25
0.4 mi·42 sec·South Main Street
3
Turn right onto US 278
0.4 mi·52 sec·6th Avenue South
Use the straight / right lanes.
4
Turn left onto Highway 125
5.2 mi·9 min·Highway 125
Use the left lane.
5
At end of road, turn right onto MS 25
6.5 mi·9 min·MS 25
6
Keep slight right at fork onto MS 8; MS 25
4.6 mi·7 min·MS 8; MS 25
Toward US 45 North, MS 25 South, MS 8 West: Tupelo, AberdeenUse the straight / right lanes.
7
Turn left onto MS 25
8.9 mi·15 min·MS 25
Use the left lane.
8
Take the ramp onto MS 25
0.7 mi·1 min·MS 25
Toward US 45 Alternate South, MS 25 South: West Point
9
Merge onto US 45 ALT; MS 25
15 mi·20 min·US Highway 45 Alternate
Use the straight lane.
10
Take the exit onto MS 25
12 mi·13 min·MS 25
Toward US 82 West, MS 12 West, MS 25 South: Starkville
11
Take the exit onto MS 25
5.0 mi·6 min·MS 25
Toward MS 25 South: Louisville
12
Continue on MS 25
1.9 mi·2 min·MS 25
Use the left lane.
13
Keep slight right at fork onto MS 25
25 mi·28 min·MS 25
14
Take the exit onto MS 25
93 mi·1 hr 47 min·MS 25
15
At end of road, turn left onto Old Canton Road
0.2 mi·20 sec·Old Canton Road
16
Turn straight onto US 51
0.3 mi·33 sec·North State Street
17
Turn right onto East Woodrow Wilson Avenue
2.9 mi·5 min·East Woodrow Wilson Avenue
18
Continue on Bullard Street
1.3 mi·2 min·Bullard Street
19
Turn straight onto West Capitol Street
0.2 mi·19 sec·West Capitol Street
20
Continue on Clinton Boulevard
4.0 mi·7 min·Clinton Boulevard
21
Turn right onto Oakwood Drive
0.5 mi·1 min·Oakwood Drive
22
Turn right onto Hester Street
0.1 mi·24 sec·Hester Street
23
Turn left onto East Leake Street
310 ft·14 sec·East Leake Street
24
Turn right onto Hester Street
0.1 mi·31 sec·Hester Street
25
At end of road, turn left onto Dunton Road
452 ft·19 sec·Dunton Road
26
Arrive at destination
Dunton Road
Trip Plan
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 94.3 miles from Amory, MS, or about 2h 5m into the drive.
The longest continuous stretch on this route runs about 152.9 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 42 miles or 1h 5m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 94.3 miles or 2h 5m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 15m
Traffic, exits, and arrival timing usually matter more near Clinton, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving Amory, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Amory, MS
This is one driving day of about 188.7 miles and 4h 3m.
Your first comfortable stop window is around 42 miles from Amory, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on MS 25 for about 152.9 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 94.3 mi from Amory, MS
· 2h 5m into the drive
The midpoint is around 94.3 miles from Amory, MS, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel check
Top up before MS 25 if your tank is already low. That segment runs about 152.9 miles.
Arriving in Clinton, MS
The final approach into Clinton, MS usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Clinton, MS.
After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
National Parks Near This Route
Worth a detour if your schedule allows.
Medgar and Myrlie Evers Home National Monument
National Monument
Medgar and Myrlie Evers were partners in the civil rights struggle. The assassination of Medgar Evers in the carport of their home on June 12, 1963, was the first murder of a nationally significant le...
1 mi from route
~3 min detour
Free
near mile 182.2
In July, 1864, federal forces, including men from the United States Colored Troops, marched into Tupelo, Mississippi. Disorganized Confederate soldiers fought fiercely but could not overpower the fede...
The Natchez Trace National Scenic Trail is five sections of hiking trail running roughly parallel to the 444-mile long Natchez Trace Parkway scenic motor road. The foot trails total more than 60 miles...
Station data from NREL Alternative Fuel Stations database.
Driving Electric?
About $20 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
56.6
0
$19.81
$9.06
Efficient EV
47.2
0
$16.51
$7.55
EV Truck/SUV
75.5
0
$26.42
$12.08
Gas CO2
66 kg
EV CO2
22 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Amory, MS
Afternoon
in Amory on Friday
Local time
1:59 PM
CDT
Current temp
53°F
Unavailable
Live forecast
Destination
Clinton, MS
Afternoon
in Clinton on Friday
Local time
1:59 PM
CDT
Current temp
54°F
Unavailable
Live forecast
79°F
Philadelphia, MS
94 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
1 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
4h 3m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Amory, MS to Clinton, MS covers 188.7 miles and takes about 4h 3m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are MS 25, US Highway 45 Alternate, Highway 125. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 94.3 miles from Amory, MS. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $28.50 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 19 significant decision points across 188.7 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 0.4 miles (US 278 / 6th Avenue South): Lane positioning matters here; at 0.7 miles (Highway 125): Lane positioning matters here; at 5.9 miles (MS 25): Navigation decision point.
On the drive from Amory, MS to Clinton, MS, road signs begin pointing toward Aberdeen along the way.
How this page is built
Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, NREL for EV charging, and NPS for national parks. See our methodology for refresh cadence and limitations.
