Anaheim, CA to Mission District, CA is 407.5 miles and takes about 7h 37m via Westside Freeway, Golden State Freeway, and I 5 Truck, with a fuel budget near $94 and enough daylight to finish in a day. This trip stays within California's Pacific Coast region, offering a direct highway-focused experience. It's a solid option if you're looking for a straightforward drive with minimal detours. Consider this route for its efficiency when you need to cover ground between these two Southern and Northern California points.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
2 planned breaks
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
203.7 miles from Anaheim, CA
A natural place for your longest stop of the day
, about 3h 49m into the drive
.
Anaheim is a city in Orange County, California. It is best known for being the home of Disneyland. Its second claim to fame is hosting the National Hockey League's Anaheim Ducks and Major League Baseball's Los Angeles Angels.
Doable as a same-day drive at 7h 37m. Total distance: 407.5 miles.
Family Friendly
Moderate complexity with 2 natural rest stops along the way.
Solo Traveler
7h 37m drive, plan rest stops for pacing.
Drive Character
Expect a highway-focused drive for this journey, with 98% of the route utilizing major freeways. You'll primarily be on the Westside Freeway and the Golden State Freeway, with a segment on I 5 Truck. The longest uninterrupted stretch you'll encounter is 225.6 miles on the Westside Freeway. This means consistent speed and limited opportunities for spontaneous stops on the main arteries.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 32 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Westside Freeway is the longest continuous segment at about 225.6 miles.
How Hard Is This Drive?
This is a straightforward highway drive that stays mostly on Westside Freeway and Golden State Freeway. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 50.3 miles in near I 5 Truck.
Driving Effort8/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 27 significant decision points across 407.5 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 50.3 miles (I 5 Truck): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 110.2 miles (I 5 / Westside Freeway): Highway fork - watch signs carefully. Lane positioning matters here; at 382.4 miles (I 580 / MacArthur Freeway): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
Critical Maneuvers
5 of 27 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
9
50.3 mi into trip|~1h in|I 5 Truck
Keep slight right at fork onto I 5 Truck toward I 5 Truck North, CA 14 Truck
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Exit 161A
Toward I 5 Truck North, CA 14 Truck
7
110.2 mi into trip|~2h 9m in|I 5 / Westside Freeway
Keep slight right at fork onto I 5 / Westside Freeway toward I 5 North
Highway fork - watch signs carefully. Lane positioning matters here
Use the straight / slight right lanes.
Toward I 5 North
8
382.4 mi into trip|~7h 3m in|I 580 / MacArthur Freeway
Keep slight right at fork onto I 580 / MacArthur Freeway toward I 580: Oakland, San Francisco
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight left / slight right lanes.
Toward I 580: Oakland, San Francisco
8
405.9 mi into trip|~7h 33m in
Take the exit toward Ninth Street, Civic Center
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 1C
Toward Ninth Street, Civic Center
9
406 mi into trip|~7h 33m in
Keep slight right at fork toward 9th Street, Civic Center
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Toward 9th Street, Civic Center
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Anaheim, CA to Mission District, CA, road signs begin pointing toward San Francisco along the way.
San Francisco
335.8 mi in|~6h 11m|via I 580
Main Roads
Road
Distance
Duration
Westside Freeway
225.6 mi
4h 1m
Golden State Freeway
50 mi
57m
I 5 Truck
37.7 mi
43m
Arthur H. Breed Junior Freeway
29.6 mi
34m
Santa Ana Freeway
21.3 mi
24m
William Elton Brown Freeway
17 mi
18m
MacArthur Freeway
15.5 mi
17m
Dwight D. Eisenhower Highway
6 mi
9m
Longest stretch:
Westside Freeway
— 225.6 mi, about 4h 1m
Turn-by-Turn Driving Directions
Step-by-step road directions between Anaheim, CA and Mission District, CA.
1
Start on this road
200 ft·16 sec·this road
2
Turn left onto South Anaheim Boulevard
422 ft·21 sec·South Anaheim Boulevard
3
Turn left onto West Lincoln Avenue
1.0 mi·2 min·West Lincoln Avenue
Use the left lane.
4
Turn left
0.2 mi·14 sec
Toward I 5 North: Los Angeles
5
Merge onto I 5
3.3 mi·3 min·Santa Ana Freeway
Use the straight / slight right lanes.
6
Keep slight right at fork onto I 5
18 mi·20 min·Santa Ana Freeway
Use the straight / slight right lanes.
7
Keep slight right at fork onto I 5
25 mi·29 min·Golden State Freeway
Use the straight / slight right lanes.
8
Keep slight left at fork onto I 5
2.2 mi·2 min·Golden State Freeway
Use the straight / slight right lanes.
9
Keep slight right at fork onto I 5 Truck
1.5 mi·1 min·I 5 Truck
Exit 161AToward I 5 Truck North, CA 14 TruckUse the straight / slight right lanes.
10
Keep slight left at fork onto I 5 Truck
36 mi·41 min·I 5 Truck
Use the straight / slight right lanes.
11
Keep slight left at fork onto I 5
22 mi·25 min·Golden State Freeway
Use the straight / slight right lanes.
12
Keep slight right at fork onto I 5
226 mi·4 hr 1 min·Westside Freeway
Toward I 5 NorthUse the straight / slight right lanes.
13
Keep slight left at fork onto I 580
16 mi·17 min·William Elton Brown Freeway
Toward I 580 West: Tracy, San Francisco
14
Keep slight right at fork onto I 580 Bypass
1.1 mi·1 min·William Elton Brown Freeway
15
Merge onto I 580
18 mi·20 min·Arthur H. Breed Junior Freeway
Use the straight / slight right lanes.
16
Keep slight right at fork onto I 580
12 mi·13 min·Arthur H. Breed Junior Freeway
Use the straight / slight right lanes.
17
Keep slight right at fork onto I 580
8.3 mi·9 min·MacArthur Freeway
Toward I 580: Oakland, San FranciscoUse the slight left / slight right lanes.
18
Keep slight left at fork onto I 580
7.2 mi·8 min·MacArthur Freeway
Use the straight / slight right lanes.
19
Take the exit
0.9 mi·1 min
Exit 19AToward I 80 West: San Francisco
20
Merge onto I 80
0.2 mi·17 sec·Dwight D. Eisenhower Highway
Toward I 80 West: San FranciscoUse the straight / slight right lanes.
21
Turn slight left onto I 80
0.4 mi·33 sec·Dwight D. Eisenhower Highway
22
Keep slight left at fork onto I 80
5.5 mi·8 min·Dwight D. Eisenhower Highway
Use the slight left lane.
23
Continue on I 80
0.3 mi·24 sec·Route 80
Use the straight / left / right lanes.
24
Continue on I 80
0.8 mi·1 min·Route 80
Exit 2AUse the straight / slight left lanes.
25
Take the exit
0.2 mi·13 sec
Exit 1CToward Ninth Street, Civic CenterUse the slight right lane.
26
Keep slight right at fork
288 ft·6 sec
Toward 9th Street, Civic CenterUse the slight right lane.
27
Continue on Harrison Street
0.7 mi·2 min·Harrison Street
Use the straight / right lanes.
28
Turn right onto 16th Street
0.1 mi·20 sec·16th Street
Use the right lane.
29
Turn left onto Folsom Street
0.2 mi·38 sec·Folsom Street
30
Turn right onto 18th Street
0.2 mi·48 sec·18th Street
31
Turn left onto Mission Street
0.1 mi·31 sec·Mission Street
32
Arrive at destination
Mission Street
Trip Plan
Given the 7h 37m duration, leaving Anaheim early in the morning is recommended to maximize daylight. With 2 recommended stops, you can plan for a mid-drive break and another closer to your destination. The longest stretch of highway is over 225 miles, so be sure to fuel up before embarking on that segment. While the drive is doable in one day, consider splitting it if you prefer a more relaxed pace.
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
You can normally do this drive in one day.
Plan roughly 2 meaningful breaks for fuel, food, and rest.
The halfway point lands around 203.7 miles from Anaheim, CA, or about 3h 49m into the drive.
The longest continuous stretch on this route runs about 225.6 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 90 miles or 1h 46m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 203.7 miles or 3h 49m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 6h 23m
Traffic, exits, and arrival timing usually matter more near Mission District, CA than in the middle of the route.
Before You Leave
+
Open the route before leaving Anaheim, CA so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
+
Pick one backup stop option before the midpoint in case traffic changes your pacing.
Day 1
Settle into the route from Anaheim, CA
This is one driving day of about 407.5 miles and 7h 37m.
Your first comfortable stop window is around 90 miles from Anaheim, CA.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 2 real breaks rather than only quick fuel stops.
The longest stretch is on Westside Freeway for about 225.6 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 203.7 mi from Anaheim, CA
· 3h 49m into the drive
The midpoint is around 203.7 miles from Anaheim, CA, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel check
Top up before Westside Freeway if your tank is already low. That segment runs about 225.6 miles.
Arriving in Mission District, CA
The final approach into Mission District, CA usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Mission District, CA.
After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
National Parks Near This Route
Worth a detour if your schedule allows.
San Francisco Maritime National Historical Park
National Historical Park
Established in 1988, San Francisco Maritime National Historical Park celebrates America’s maritime heritage on the Pacific Coast. Our 50-acre park has grown around Aquatic Park Cove, a protected area...
3 mi from route
~9 min detour
Free
near mile 407.5
Rosie the Riveter WWII Home Front National Historical Park
National Historical Park
Celebrate and honor the contributions and sacrifices of American civilians on the WWII home front. Discover how diverse communities lived, worked, and interacted. Many faces, many stories, many truths...
11 mi from route
~27 min detour
Free
near mile 407.5
Experience a park so rich it supports 19 distinct ecosystems with over 2,000 plant and animal species. Go for a hike, enjoy a vista, have a picnic or learn about the centuries of overlapping history f...
12 mi from route
~30 min detour
Free
near mile 407.5
Walk among old growth coast redwoods, cooling their roots in the fresh water of Redwood Creek and lifting their crowns to reach the sun and fog. Federally protected as a National Monument since 1908,...
13 mi from route
~32 min detour
$15
near mile 407.5
On July 17, 1944, a massive explosion jolted the San Francisco East Bay area, shattering windows and lighting up the night sky. At Port Chicago Naval Magazine, 320 men were killed instantly when two s...
21 mi from route
~51 min detour
Free
near mile 393.4
The Santa Monica Mountains offer easy access to surprisingly wild places. Experience the famous beaches of Malibu or explore more than 500 miles of trails. The park abounds with historical and cultura...
22 mi from route
~56 min detour
Free
near mile 56.2
Park data from the National Park Service API. Alerts update every 2 hours.
Fuel & Cost
Regular Gas
$93.66 one way
$187.32 round trip
$5.84/gal25.4 MPG avg143 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$6.02
$96.52
$193.03
premium
$6.18
$99.10
$198.20
diesel
$5.61
$89.97
$179.94
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$94
Meals
$25–$50
Total
$119–$144
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 142.6 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $43 in charging
· 1 stop
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
122.3
1
$42.79
$19.56
Efficient EV
101.9
1
$35.66
$16.30
EV Truck/SUV
163
2
$57.05
$26.08
Gas CO2
143 kg
EV CO2
48 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 16, 2026
Origin
Anaheim, CA
Evening
in Anaheim on Friday
Local time
7:35 PM
PDT
Current temp
74°F
Partly Sunny
SW 0 to 10 mph0% chanceLive forecast
Destination
Mission District, CA
Evening
in Mission District on Friday
Local time
7:35 PM
PDT
Current temp
44°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
30 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
7h 37m on the road
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Anaheim, CA to Mission District, CA covers 407.5 miles and takes about 7h 37m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are Westside Freeway, Golden State Freeway, I 5 Truck. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 203.7 miles from Anaheim, CA. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $93.66 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.
Plan about 2 meaningful breaks for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 27 significant decision points across 407.5 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 50.3 miles (I 5 Truck): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 110.2 miles (I 5 / Westside Freeway): Highway fork - watch signs carefully. Lane positioning matters here; at 382.4 miles (I 580 / MacArthur Freeway): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
On the drive from Anaheim, CA to Mission District, CA, road signs begin pointing toward San Francisco along the way.
Yes. Nearby national parks include San Francisco Maritime National Historical Park, Rosie the Riveter WWII Home Front National Historical Park and Golden Gate National Recreation Area. There are 6 parks within detour distance of this route.
How this page is built
Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.
