The drive from Brookdale, SC to Myrtle Beach, SC covers 141.7 miles and takes about 3h 2m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on I 95, Turbeville Highway, Highway 378 for much of the mileage,
and the overall profile is mixed drive.
The longest uninterrupted segment is about 38.5 miles on I 95.
At current regular gas prices, budget about $22.19 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
70.8 miles from Brookdale, SC
A natural place for your longest stop of the day
, about 1h 24m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 3h 2m. Total distance: 141.7 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
3h 2m drive, comfortable solo distance.
Scenic Drive
Mixed drive route profile with national parks nearby.
Drive Character
The drive from Brookdale, SC to Myrtle Beach, SC covers 141.7 miles and takes about 3h 2m, using a mix of highways and local roads.
Expect a mix of faster highway mileage and slower local approaches near the beginning or end.
There are about 26 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
I 95 is the longest continuous segment at about 38.5 miles.
How Hard Is This Drive?
This route mixes highway mileage with some local-road sections near the start or finish. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.3 miles in near Old Cameron Road.
Driving Effort8/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 16 significant decision points across 141.7 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 0.3 miles (Old Cameron Road): Navigation decision point; at 7.9 miles: Exit ramp - move to the correct lane early; at 23 miles (US 15; US 301): Exit ramp - move to the correct lane early. Lane positioning matters here.
Critical Maneuvers
5 of 16 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
5
0.3 mi into trip|~1m in|Old Cameron Road
At end of road, turn left onto Old Cameron Road
Navigation decision point
5
7.9 mi into trip|~11m in
Take the exit toward US 301 North: Santee
Exit ramp - move to the correct lane early
Exit 154-B
Toward US 301 North: Santee
5
23 mi into trip|~30m in|US 15; US 301
Take the exit onto US 15; US 301
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the right lane.
5
23.3 mi into trip|~31m in|I 95
Merge onto I 95
Merge point - match speed before joining. Lane positioning matters here
Use the straight / slight right lanes.
7
62 mi into trip|~1h 12m in
Keep slight right at fork toward US 378 East: Turbeville, Lake City, Myrtle Beach
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward US 378 East: Turbeville, Lake City, Myrt...
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Brookdale, SC and Myrtle Beach, SC, road signs point toward Sumter and Lake City.
Sumter
61.8 mi in|~1h 12m
Lake City
62 mi in|~1h 12m
Main Roads
Road
Distance
Duration
I 95
38.5 mi
41m
Turbeville Highway
36.1 mi
43m
Highway 378
22.9 mi
32m
Five Chop Road
14.8 mi
18m
Highway 501 East
10.7 mi
16m
I 26
5.6 mi
5m
Clarence Coker Highway
3.5 mi
4m
US 501
2 mi
3m
Longest stretch:
I 95
— 38.5 mi, about 41m
Turn-by-Turn Driving Directions
Step-by-step road directions between Brookdale, SC and Myrtle Beach, SC.
1
Start on Dellwood Drive
424 ft·20 sec·Dellwood Drive
2
Turn right onto Shadow Lawn Drive
0.2 mi·1 min·Shadow Lawn Drive
3
At end of road, turn left onto Old Cameron Road
0.1 mi·25 sec·Old Cameron Road
4
Continue on SC 33
1.7 mi·3 min·Russell Street
5
Take the ramp
0.2 mi·29 sec
Toward I 26 East: Charleston
6
Merge onto I 26
5.6 mi·5 min·I 26
7
Take the exit
0.3 mi·36 sec
Exit 154-BToward US 301 North: Santee
8
Merge onto US 301
15 mi·18 min·Five Chop Road
9
Take the exit onto US 15; US 301
0.3 mi·33 sec·US 15; US 301
Use the right lane.
10
Merge onto I 95
38 mi·41 min·I 95
Use the straight / slight right lanes.
11
Take the exit
0.3 mi·36 sec
Toward US 378: Turbeville, Sumter
12
Keep slight right at fork
288 ft·7 sec
Toward US 378 East: Turbeville, Lake City, Myrtle Beach
13
Merge onto US 378
0.9 mi·1 min·Myrtle Beach Highway
14
Continue on US 378
3.5 mi·4 min·Clarence Coker Highway
15
Continue on US 301; US 378
0.5 mi·1 min·Main Street
16
Continue on US 301; US 378
36 mi·43 min·Turbeville Highway
17
Continue on US 378
23 mi·32 min·Highway 378
18
Continue on US 378
1.0 mi·2 min·Wright Boulevard
19
Turn right onto US 501; US 701
1.5 mi·2 min·Church Street
20
Continue on US 501
11 mi·16 min·Highway 501 East
Use the straight / slight right lanes.
21
Turn straight onto US 501
2.0 mi·3 min·US 501
Use the straight / right lanes.
22
Turn slight right onto 8th Avenue North
248 ft·14 sec·8th Avenue North
23
Turn right onto US 17 Business
0.3 mi·40 sec·North Kings Highway
24
Turn left onto 5th Avenue North
198 ft·11 sec·5th Avenue North
25
Turn right
196 ft·14 sec
26
Arrive at destination
Trip Plan
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 70.8 miles from Brookdale, SC, or about 1h 24m into the drive.
The longest continuous stretch on this route runs about 38.5 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 31 miles or 39m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 70.8 miles or 1h 24m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 21m
Traffic, exits, and arrival timing usually matter more near Myrtle Beach, SC than in the middle of the route.
Before You Leave
+
Open the route before leaving Brookdale, SC so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Brookdale, SC
This is one driving day of about 141.7 miles and 3h 2m.
Your first comfortable stop window is around 31 miles from Brookdale, SC.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 95 for about 38.5 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 70.8 mi from Brookdale, SC
· 1h 24m into the drive
Place data sourced from public business listings. Hours and availability may vary.
National Parks Near This Route
Worth a detour if your schedule allows.
Congaree National Park
National Park
Astonishing biodiversity exists in Congaree National Park, the largest intact expanse of old growth bottomland hardwood forest remaining in the southeastern United States. Waters from the Congaree and...
Station data from NREL Alternative Fuel Stations database.
Driving Electric?
About $15 in charging
· 0 stops
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
42.5
0
$14.88
$6.80
Efficient EV
35.4
0
$12.40
$5.67
EV Truck/SUV
56.7
0
$19.84
$9.07
Gas CO2
50 kg
EV CO2
17 kg (66% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Brookdale, SC
Morning
in Brookdale on Friday
Local time
9:37 AM
EDT
Current temp
49°F
Unavailable
Live forecast
Destination
Myrtle Beach, SC
Morning
in Myrtle Beach on Friday
Local time
9:37 AM
EDT
Current temp
58°F
Unavailable
Live forecast
74°F
Lake City, SC
71 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
9 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
3h 2m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Brookdale, SC to Myrtle Beach, SC covers 141.7 miles and takes about 3h 2m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are I 95, Turbeville Highway, Highway 378. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 70.8 miles from Brookdale, SC. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $22.16 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. A short stop every 2 to 3 hours is enough for this drive.
This is a demanding drive. With 16 significant decision points across 141.7 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 0.3 miles (Old Cameron Road): Navigation decision point; at 7.9 miles: Exit ramp - move to the correct lane early; at 23 miles (US 15; US 301): Exit ramp - move to the correct lane early. Lane positioning matters here.
Between Brookdale, SC and Myrtle Beach, SC, road signs point toward Sumter and Lake City.
How this page is built
Compiled and maintained by the Trip.ovh planning team at COD Solutions Oy (Helsinki). Each route is built from authoritative open government and mapping datasets rather than crowdsourced reviews. Distances and geometry come from
OSRM
over
OpenStreetMap.
Fuel cost uses
EIA
weekly regional averages.
EV charging comes from the
NREL Alternative Fuels
dataset.
National park proximity is from the
NPS API.
Pages are published only after passing our data-quality checks; our
methodology page
documents refresh cadence, editorial standards, and known limitations.
