The drive from Brookhaven, MS to Greenville, MS covers 172.3 miles and takes about 3h 29m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on I 55, US 49W, Medgar Evers Boulevard for much of the mileage,
and the overall profile is highway-focused drive.
The longest uninterrupted segment is about 49 miles on I 55.
At current regular gas prices, budget about $26.02 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
86.2 miles from Brookhaven, MS
A natural place for your longest stop of the day
, about 1h 40m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 3h 29m. Total distance: 172.3 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
3h 29m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (75%). Some complex stretches to watch for.
Drive Character
This is a 3h 29m highway drive covering 172.3 miles, with most of the trip on I 55 and US 49W. The longest continuous stretch is about 49 miles on I 55.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 23 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
I 55 is the longest continuous segment at about 49 miles.
How Hard Is This Drive?
This is a straightforward highway drive that stays mostly on I 55 and US 49W. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.6 miles in near MS 550 / West Congress Street.
Driving Effort8/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 18 significant decision points across 172.3 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 0.6 miles (MS 550 / West Congress Street): Navigation decision point; at 51.9 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 52.1 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Critical Maneuvers
5 of 18 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
4
0.6 mi into trip|~1m in|MS 550 / West Congress Street
Turn left onto MS 550 / West Congress Street
Navigation decision point
7
51.9 mi into trip|~57m in
Take the exit toward I 20 West, US 49 North: Vicksburg, Yazoo City
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Exit 92C
Toward I 20 West, US 49 North: Vicksburg, Yazoo...
7
52.1 mi into trip|~58m in
Keep slight left at fork toward I 20 West, US 49 North: Vicksburg, Yazoo City
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward I 20 West, US 49 North: Vicksburg, Yazoo...
5
54.7 mi into trip|~1h 1m in|US 49
Take the exit onto US 49 toward I 220 North, I 49 North: North Jackson, Yazoo City
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Toward I 220 North, I 49 North: North Jackson,...
5
99.7 mi into trip|~1h 56m in|US 49W
Take the exit onto US 49W toward US 49W North, MS 3 South: Indianola, Vicksburg
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Toward US 49W North, MS 3 South: Indianola, Vic...
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Brookhaven, MS and Greenville, MS, road signs point toward Yazoo City and Vicksburg.
Yazoo City
51.9 mi in|~57m
Vicksburg
99.7 mi in|~1h 56m|via US 49W
Main Roads
Road
Distance
Duration
I 55
49 mi
52m
US 49W
46.7 mi
56m
Medgar Evers Boulevard
39.5 mi
48m
US 82
15.8 mi
19m
MS 182
9.2 mi
13m
US 49
5.5 mi
6m
I 20
2.4 mi
2m
South Main Street
0.9 mi
2m
Longest stretch:
I 55
— 49 mi, about 52m
Turn-by-Turn Driving Directions
Step-by-step road directions between Brookhaven, MS and Greenville, MS.
1
Start on MS 184
0.5 mi·1 min·East Monticello Street
2
Turn right onto MS 550
0.1 mi·15 sec·Schwem Avenue
3
Turn left onto MS 550
528 ft·10 sec·West Congress Street
4
Continue on MS 550
0.3 mi·39 sec·Union Church Road
5
Turn right onto US 51
0.7 mi·1 min·US 51
6
Turn left onto Union St Extended Northeast
0.8 mi·1 min·Union St Extended Northeast
7
Take the ramp
0.3 mi·39 sec
8
Merge onto I 55
49 mi·52 min·I 55
9
Keep slight right at fork onto I 55
0.2 mi·13 sec·I 55
10
Take the exit
0.2 mi·22 sec
Exit 92CToward I 20 West, US 49 North: Vicksburg, Yazoo City
11
Keep slight left at fork
0.2 mi·29 sec
Toward I 20 West, US 49 North: Vicksburg, Yazoo City
12
Merge onto I 20; US 49
2.4 mi·2 min·I 20; US 49
13
Take the exit onto US 49
5.2 mi·6 min·US 49
Toward I 220 North, I 49 North: North Jackson, Yazoo City
14
Take the exit onto US 49
0.3 mi·33 sec·US 49
Toward US 49 North: Yazoo City
15
Merge onto US 49
39 mi·48 min·Medgar Evers Boulevard
16
Take the exit onto US 49W
47 mi·56 min·US 49W
Toward US 49W North, MS 3 South: Indianola, Vicksburg
17
Turn left onto US 82
2.4 mi·3 min·US 82
18
Keep slight left at fork onto US 82
0.4 mi·29 sec·US 82
19
Keep slight left at fork onto US 82
13 mi·15 min·US 82
20
Turn right onto MS 182
9.2 mi·13 min·MS 182
21
Turn right onto South Main Street
0.9 mi·2 min·South Main Street
22
Turn right onto MS 814
10 ft·0 sec·South Broadway Street
23
Arrive at destination
MS 814
Trip Plan
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 86.2 miles from Brookhaven, MS, or about 1h 40m into the drive.
The longest continuous stretch on this route runs about 49 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 38 miles or 42m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 86.2 miles or 1h 40m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 47m
Traffic, exits, and arrival timing usually matter more near Greenville, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving Brookhaven, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Brookhaven, MS
This is one driving day of about 172.3 miles and 3h 29m.
Your first comfortable stop window is around 38 miles from Brookhaven, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 55 for about 49 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 86.2 mi from Brookhaven, MS
· 1h 40m into the drive
Place data sourced from public business listings. Hours and availability may vary.
National Parks Near This Route
Worth a detour if your schedule allows.
Medgar and Myrlie Evers Home National Monument
National Monument
Medgar and Myrlie Evers were partners in the civil rights struggle. The assassination of Medgar Evers in the carport of their home on June 12, 1963, was the first murder of a nationally significant le...
Park data from the National Park Service API. Alerts update every 2 hours.
Fuel & Cost
Regular Gas
$26.02 one way
$52.04 round trip
$3.84/gal25.4 MPG avg60 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.21
$28.57
$57.13
premium
$4.56
$30.93
$61.85
diesel
$5.61
$38.04
$76.08
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$26
Meals
$25–$50
Total
$51–$76
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 60.3 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $18 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
51.7
0
$18.09
$8.27
Efficient EV
43.1
0
$15.08
$6.89
EV Truck/SUV
68.9
0
$24.12
$11.03
Gas CO2
60 kg
EV CO2
20 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 16, 2026
Origin
Brookhaven, MS
Afternoon
in Brookhaven on Thursday
Local time
3:26 PM
CDT
Current temp
55°F
Unavailable
Live forecast
Destination
Greenville, MS
Afternoon
in Greenville on Thursday
Local time
3:26 PM
CDT
Current temp
86°F
Mostly Sunny
SSW 10 to 15 mph13% chanceLive forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
31 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
3h 29m on the road
The weather snapshot is not static. If you are leaving later, give both cities one more quick forecast check before departure.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Brookhaven, MS to Greenville, MS covers 172.3 miles and takes about 3h 29m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are I 55, US 49W, Medgar Evers Boulevard. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 86.2 miles from Brookhaven, MS. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $26.02 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. A short stop every 2 to 3 hours is enough for this drive.
This is a demanding drive. With 18 significant decision points across 172.3 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 0.6 miles (MS 550 / West Congress Street): Navigation decision point; at 51.9 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 52.1 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Between Brookhaven, MS and Greenville, MS, road signs point toward Yazoo City and Vicksburg.
