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Trip from Cape Girardeau, MO to Berkeley, MO

Last recalculated Apr 15, 2026

Drive Time

2h 29m

Distance

123.8 mi

199 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$19

one way

Best Time to Leave

Save up to 30 min
4 AM
2h 19m ★
6 AM
2h 29m
8 AM
2h 49m
10 AM
2h 36m
12 PM
2h 34m
3 PM
2h 37m
5 PM
2h 48m
8 PM
2h 23m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

city in Cape Girardeau and Scott Counties in the U.S. state of Missouri

Cape Girardeau, MO

Wikimedia Commons

Downtown Berkeley, MO, MO

Berkeley, MO

Valeria Boltneva

Trip Overview

The drive from Cape Girardeau, MO to Berkeley, MO covers 123.8 miles and takes about 2h 29m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on North Kingshighway, I 55 North, Rosa Parks Highway for much of the mileage, and the overall profile is turn-heavy local drive. At current regular gas prices, budget about $19.35 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is realistic if you keep stops short.

Break Rhythm

0 planned breaks

A short stop every 2 to 3 hours is enough for this drive.

Midpoint

61.9 miles from Cape Girardeau, MO

A natural place for your longest stop of the day , about 1h 14m into the drive .

Drive Character

Expect a 2h 29m drive with frequent turns across 123.8 miles of local and secondary roads.

This route has more turning and local-road decision points than a simple highway run.
There are about 21 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
North Kingshighway is one of the defining roads on this drive.

How Hard Is This Drive?

Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. Navigation is very simple - set it and forget it for most of the drive.

Route Complexity 1/10

Very easy - short and simple to drive

The drive from Cape Girardeau, MO to Berkeley, MO is easy. At 2h 29m with 0% highway, most drivers will find it relaxed and low-stress.

Where does it get tricky?

This route does not have any notably tricky sections. Most of the drive from Cape Girardeau, MO to Berkeley, MO is straightforward, with well-signed roads and simple exits.

Main Roads

Road Distance Duration
North Kingshighway
I 55 North
Rosa Parks Highway
Reavis Barracks Road
Mackenzie Road
Reavis Road
Tesson Ferry Road
South Rock Hill Road

Some road-level metrics are being recalculated.

Longest stretch: North Kingshighway — detailed segment metrics are refreshing.

Turn-by-Turn Driving Directions

Step-by-step road directions between Cape Girardeau, MO and Berkeley, MO.

1

Start on Broadway Street

2.0 mi · 3 min · Broadway Street
2

Turn right onto North Kingshighway

3.6 mi · 5 min · North Kingshighway
3

Take the ramp slight right toward I 55 North: Saint Louis

0.3 mi · 39 sec · I 55 North: Saint Louis
4

Merge slight left

95 mi · 1 hr 42 min
5

Continue on Rosa Parks Highway

4.3 mi · 5 min · Rosa Parks Highway
6

Take the exit slight right toward Reavis Barracks Road

0.1 mi · 24 sec · Reavis Barracks Road
7

Turn left onto Reavis Barracks Road

0.8 mi · 1 min · Reavis Barracks Road
8

Continue on Mackenzie Road

0.5 mi · 1 min · Mackenzie Road
9

Turn left onto Reavis Road

0.5 mi · 1 min · Reavis Road
10

Turn right onto Tesson Ferry Road

0.5 mi · 58 sec · Tesson Ferry Road
11

Continue on South Rock Hill Road

0.6 mi · 1 min · South Rock Hill Road
12

Turn slight right

141 ft · 4 sec
13

Turn straight onto Laclede Station Road

3.5 mi · 6 min · Laclede Station Road
14

Continue on South Hanley Road

1.6 mi · 3 min · South Hanley Road
15

Turn slight right onto Eager Road

0.6 mi · 1 min · Eager Road
16

Take the ramp slight right toward I 170 North

0.4 mi · 34 sec · I 170 North
17

Merge slight right onto Inner Belt Expressway

8.5 mi · 10 min · Inner Belt Expressway
18

Take the exit slight right toward Airport Road

0.2 mi · 20 sec · Airport Road
19

Turn right onto Airport Road

0.3 mi · 41 sec · Airport Road
20

Turn left onto Evergreen Boulevard

0.3 mi · 1 min · Evergreen Boulevard
21

Arrive at your destination

Trip Plan

Morning Departure

Leave by 9 AM and you'll arrive before lunch.

Evening Departure

Even a 4 PM departure gets you there before dark in summer.

You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 61.9 miles from Cape Girardeau, MO, or about 1h 14m into the drive.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 27 miles or 32m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 61.9 miles or 1h 14m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 2h 2m

Traffic, exits, and arrival timing usually matter more near Berkeley, MO than in the middle of the route.

Before You Leave

+

Open the route before leaving Cape Girardeau, MO so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Cape Girardeau, MO

This is one driving day of about 123.8 miles and 2h 29m.

Your first comfortable stop window is around 27 miles from Cape Girardeau, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 61.9 mi from Cape Girardeau, MO · 1h 14m into the drive

census-designated place in Missouri, United States

Mid-route town

Meal stop

Imperial, MO

62 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Campton, IL

Fuel and coffee

A short stop after about 27 miles helps settle the day before fatigue starts building.

Imperial, MO

Meal break

The midpoint is around 61.9 miles from Cape Girardeau, MO, which is a good place for a longer meal and fuel stop.

Arriving in Berkeley, MO

The final approach into Berkeley, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Berkeley, MO.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$19.35 one way

$38.71 round trip

$3.97/gal 25.4 MPG avg 43 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.36 $21.25 $42.50
premium $4.89 $23.82 $47.65
diesel $5.61 $27.33 $54.67

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$19

Meals

$25–$50

Total

$44–$69

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 43.3 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $13 in charging · 0 stops · 67% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 37.1 0 $13.00 $5.94
Efficient EV 31 0 $10.83 $4.95
EV Truck/SUV 49.5 0 $17.33 $7.92

Gas CO2

43 kg

EV CO2

14 kg (67% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 15, 2026

Origin

Cape Girardeau, MO

Evening in Cape Girardeau on Wednesday

Local time

6:02 PM

CDT

Current temp

76°F

Unavailable

Live forecast

Destination

Berkeley, MO

Evening in Berkeley on Wednesday

Local time

6:02 PM

CDT

Current temp

77°F

Unavailable

Live forecast

57°F

Imperial, MO

62 mi in

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

1 degrees warmer at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

2h 29m on the road

Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Cape Girardeau, MO to Berkeley, MO covers 123.8 miles and takes about 2h 29m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are North Kingshighway, I 55 North, Rosa Parks Highway. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 61.9 miles from Cape Girardeau, MO. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $19.35 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Leave by 9 AM and you'll arrive before lunch. Even a 4 PM departure gets you there before dark in summer.
The drive from Cape Girardeau, MO to Berkeley, MO is easy. At 2h 29m with 0% highway, most drivers will find it relaxed and low-stress.
This route does not have any notably tricky sections. Most of the drive from Cape Girardeau, MO to Berkeley, MO is straightforward, with well-signed roads and simple exits.
The route from Cape Girardeau, MO to Berkeley, MO does not surface many named destination signs beyond the main corridor.

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