Drive Time
4h 10m
Distance
211.1 mi
340 km
Drive Score
10/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$32
one way
Photo: RDNE Stock project
The drive from City of Greenville, MS to Meridian, MS covers 211.1 miles and takes about 4h 10m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on I 20, North Martin Luther King Drive, Jerry Clower Boulevard for much of the mileage, and the overall profile is mixed drive. The longest uninterrupted segment is about 88 miles on I 20. At current regular gas prices, budget about $32.27 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
105.5 miles from City of Greenville, MS
A natural place for your longest stop of the day , about 2h 11m into the drive .
The drive from City of Greenville, MS to Meridian, MS covers 211.1 miles and takes about 4h 10m, using a mix of highways and local roads.
This route mixes highway mileage with some local-road sections near the start or finish. You will hit about 12 points where you need to pay attention to lane position or signs. The trickiest moment comes around 10 miles in near US 82; US 278.
Moderate - straightforward overall, but long enough or busy enough to require pacing
This drive requires moderate attention. Across 211.1 miles you will encounter 12 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: at 10 miles (US 82; US 278): Lane positioning matters here; at 72 miles (US 49W): Highway fork - watch signs carefully; at 116.2 miles (US 49): Highway fork - watch signs carefully.
These are the spots where you need to pay the most attention. Preview them before you drive.
Turn left onto US 82; US 278
Lane positioning matters here
Keep slight right at fork onto US 49W toward US 49 South: Jackson
Highway fork - watch signs carefully
Keep slight left at fork onto US 49
Highway fork - watch signs carefully
Keep slight right at fork onto I 20; US 49 toward Meridian, Hattiesburg
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Take the exit toward South US 11, North Mississippi 19: Philadelphia, Meridian Airport
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
On the drive from City of Greenville, MS to Meridian, MS, road signs begin pointing toward Hattiesburg along the way.
Hattiesburg
| Road | Distance | Duration |
|---|---|---|
| I 20 | 88 mi | 1h 35m |
| North Martin Luther King Drive | 46.2 mi | 55m |
| Jerry Clower Boulevard | 38.8 mi | 47m |
| US 82 | 15.8 mi | 19m |
| US 49 | 8.7 mi | 10m |
| MS 182 | 8.3 mi | 12m |
| 8th Street | 1.4 mi | 2m |
| US 11 | 1.2 mi | 1m |
Step-by-step road directions between City of Greenville, MS and Meridian, MS.
Start on Sandy Avenue
Turn right onto East Reed Road
Turn left onto MS 1
Continue on MS 182
Turn left onto US 82; US 278
Turn right onto US 49W
Keep slight right at fork onto US 49W
Merge onto US 49
Take the exit onto US 49
Keep slight left at fork onto US 49
Merge onto I 20; I 55; US 49
Keep slight right at fork onto I 20; US 49
Continue on I 20; I 59; US 80
Take the exit
Turn left onto US 11
Turn right onto 8th Street
Turn right onto 25th Avenue
Arrive at destination
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 40m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 105.5 miles or 2h 11m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 27m
Traffic, exits, and arrival timing usually matter more near Meridian, MS than in the middle of the route.
Open the route before leaving City of Greenville, MS so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from City of Greenville, MS
This is one driving day of about 211.1 miles and 4h 10m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 105.5 mi from City of Greenville, MS · 2h 11m into the drive
Mid-route town
Meal stop
106 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 80 miles helps settle the day before fatigue starts building.
The midpoint is around 105.5 miles from City of Greenville, MS, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before I 20 if your tank is already low. That segment runs about 88 miles.
The final approach into Meridian, MS usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Meridian, MS.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$32.27 one way
$64.54 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.26 | $35.40 | $70.79 |
| premium | $4.61 | $38.31 | $76.63 |
| diesel | $5.64 | $46.90 | $93.80 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$32
Meals
$25–$50
Total
$57–$82
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 73.9 kg one way. Prices: EIA weekly data, 2026-04-06.
Driving Electric?
About $22 in charging · 0 stops · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 63.3 | 0 | $22.17 | $10.13 |
| Efficient EV | 52.8 | 0 | $18.47 | $8.44 |
| EV Truck/SUV | 84.4 | 1 | $29.55 | $13.51 |
Gas CO2
74 kg
EV CO2
25 kg (66% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive. If you're planning ahead, check the forecast closer to your travel date.
Origin
Late night in City of Greenville on Sunday
Local time
2:32 AM
CDT
Current temp
68°F
Forecast unavailable right now
Destination
Late night in Meridian on Sunday
Local time
2:32 AM
CDT
Current temp
63°F
Forecast unavailable right now
Along the Route
85°F
Magee, MS
106 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
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