The drive from City of Portland, ME to Guilford, ME covers 132.3 miles and takes about 3h 1m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on Maine Turnpike, I 295, North Dexter Road for much of the mileage,
and the overall profile is highway-focused drive.
The longest uninterrupted segment is about 53.6 miles on Maine Turnpike.
At current regular gas prices, budget about $21.18 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
66.2 miles from City of Portland, ME
A natural place for your longest stop of the day
, about 1h 36m into the drive
.