Trip from Clearwater, FL to Key Largo, FL

Drive Time

6h 24m

Distance

327.7 mi

527 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$55

one way

EV Charging

Loading...

station data

Best Time to Leave

Save up to 38 min
4 AM
6h 12m ★
6 AM
6h 25m
8 AM
6h 50m
10 AM
6h 33m
12 PM
6h 31m
3 PM
6h 35m
5 PM
6h 48m
8 PM
6h 17m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown Clearwater, FL, FL

Clearwater, FL

Arian Fernandez

Downtown Key Largo, FL, FL

Key Largo, FL

Arian Fernandez

Trip Overview

The drive from Clearwater, FL to Key Largo, FL covers 327.7 miles and takes about 6h 24m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on Drew Street, Southbound Frontage Road, US 19 South for much of the mileage, and the overall profile is turn-heavy local drive. At current regular gas prices, budget about $54.74 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

163.8 miles from Clearwater, FL

A natural place for your longest stop of the day , about 3h 12m into the drive .

Drive Character

Expect a 6h 24m drive with frequent turns across 327.7 miles of local and secondary roads.

This route has more turning and local-road decision points than a simple highway run.
There are about 28 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Drew Street is one of the defining roads on this drive.

How Hard Is This Drive?

Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. There are only a few real navigation decisions along the way.

Route Complexity 3/10

Easy - simple navigation with a manageable amount of wheel time

The route itself is not hard, but at 6h 24m, endurance matters. Plan breaks every 2-3 hours. The 0 decision points are all manageable with basic attention.

Where does it get tricky?

This route does not have any notably tricky sections. Most of the drive from Clearwater, FL to Key Largo, FL is straightforward, with well-signed roads and simple exits.

Main Roads

Road Distance Duration
Drew Street Unavailable Refreshing
Southbound Frontage Road Unavailable Refreshing
US 19 South Unavailable Refreshing
Highway 19 North Unavailable Refreshing
34th Street North Unavailable Refreshing
54th Avenue North Unavailable Refreshing
I 275 South Unavailable Refreshing
Sunshine Skyway Bridge Unavailable Refreshing

Per-road distance and duration are being refreshed from OSRM for this route.

Longest stretch: Drew Street — detailed segment metrics are refreshing.

Turn-by-Turn Driving Directions

Step-by-step road directions between Clearwater, FL and Key Largo, FL.

1

Start on North Fort Harrison Avenue

0.2 mi · 27 sec · North Fort Harrison Avenue
2

Turn right onto Drew Street

4.2 mi · 8 min · Drew Street
3

Take the ramp slight right

197 ft · 5 sec
4

Merge slight left onto Southbound Frontage Road

354 ft · 9 sec · Southbound Frontage Road
5

Take the exit straight toward US 19 South

0.2 mi · 31 sec · US 19 South
6

Merge slight left onto US Highway 19 North

5.7 mi · 7 min · US Highway 19 North
7

Keep slight left to continue on US Highway 19 North

4.4 mi · 6 min · US Highway 19 North
8

Continue on 34th Street North

0.6 mi · 1 min · 34th Street North
9

Turn left onto 54th Avenue North

0.8 mi · 1 min · 54th Avenue North
10

Take the ramp slight right toward I 275 South

0.2 mi · 31 sec · I 275 South
11

Merge slight left

10 mi · 11 min
12

Keep slight left

0.3 mi · 17 sec
13

Merge slight right onto Sunshine Skyway Bridge

13 mi · 15 min · Sunshine Skyway Bridge
14

Keep slight left to continue on I 75 South: Naples

1.1 mi · 2 min · I 75 South: Naples
15

Merge slight left

28 mi · 30 min
16

Keep slight left

176 mi · 3 hr 8 min
17

Take the exit slight right toward US 27: Miami, South Bay

0.2 mi · 21 sec · US 27: Miami, South Bay
18

Keep slight right to continue on US 27 South: Miami

0.5 mi · 59 sec · US 27 South: Miami
19

Merge slight left

9.2 mi · 11 min
20

Keep slight right

8.6 mi · 11 min
21

Take the exit right toward Florida's Turnpike South: Homestead, Key West

0.3 mi · 32 sec · Florida's Turnpike South: Homestead, Key West
22

Merge slight left onto Homestead Extension of Florida's Turnpike

35 mi · 40 min · Homestead Extension of Florida's Turnpike
23

Keep slight left

0.6 mi · 1 min
24

Merge slight left onto Dixie Highway

19 mi · 26 min · Dixie Highway
25

Continue on Overseas Highway

9.3 mi · 15 min · Overseas Highway
26

Continue on Overseas Highway

453 ft · 28 sec · Overseas Highway
27

Turn right onto Harbor Drive

308 ft · 14 sec · Harbor Drive
28

Arrive at your destination

Trip Plan

Morning Departure

Start early — leave by 6-7 AM to arrive at a reasonable hour.

Evening Departure

This is a long drive — plan for a morning departure or consider splitting it into two days.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 163.8 miles from Clearwater, FL, or about 3h 12m into the drive.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 80 miles or 1h 33m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 163.8 miles or 3h 12m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 5h 15m

Traffic, exits, and arrival timing usually matter more near Key Largo, FL than in the middle of the route.

Before You Leave

+

Open the route before leaving Clearwater, FL so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Clearwater, FL

This is one driving day of about 327.7 miles and 6h 24m.

Your first comfortable stop window is around 80 miles from Clearwater, FL.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 163.8 mi from Clearwater, FL · 3h 12m into the drive

Downtown Bonita Springs, FL, FL

Mid-route town

Meal stop

Bonita Springs, FL

164 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

St. Petersburg, FL

Fuel and coffee

A short stop after about 80 miles helps settle the day before fatigue starts building.

Bonita Springs, FL

Meal break

The midpoint is around 163.8 miles from Clearwater, FL, which is a good place for a longer meal and fuel stop.

Arriving in Key Largo, FL

The final approach into Key Largo, FL usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Key Largo, FL.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$54.74 one way

$109.48 round trip

$4.24/gal 25.4 MPG avg 115 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.60 $59.30 $118.59
premium $4.90 $63.17 $126.33
diesel $5.64 $72.80 $145.61

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$55

Meals

$25–$50

Total

$80–$105

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 114.7 kg one way. Prices: EIA weekly data, 2026-04-06.

Driving Electric?

About $34 in charging · 1 stop · 67% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 98.3 1 $34.41 $15.73
Efficient EV 81.9 0 $28.67 $13.11
EV Truck/SUV 131.1 1 $45.88 $20.97

Gas CO2

115 kg

EV CO2

38 kg (67% less)

Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast data refreshed 3 days ago

Origin

Clearwater, FL

Morning in Clearwater on Monday

Local time

11:26 AM

EDT

Current temp

69°F

Unavailable

Live forecast

Destination

Key Largo, FL

Morning in Key Largo on Monday

Local time

11:26 AM

EDT

Current temp

75°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

6 degrees warmer at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

6h 24m on the road

Start early — leave by 6-7 AM to arrive at a reasonable hour.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Clearwater, FL to Key Largo, FL covers 327.7 miles and takes about 6h 24m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are Drew Street, Southbound Frontage Road, US 19 South. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 163.8 miles from Clearwater, FL. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $54.74 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
The route itself is not hard, but at 6h 24m, endurance matters. Plan breaks every 2-3 hours. The 0 decision points are all manageable with basic attention.
This route does not have any notably tricky sections. Most of the drive from Clearwater, FL to Key Largo, FL is straightforward, with well-signed roads and simple exits.
The route from Clearwater, FL to Key Largo, FL does not surface many named destination signs beyond the main corridor.

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Explore More

Return Trip

Key Largo, FL to Clearwater, FL

Plan the drive back the other way.

330.3 mi 5h 16m

Explore more options from Clearwater, FL or browse trips ending in Key Largo, FL.

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