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Trip from Clemson, SC to Bluffton, SC

Compiled and reviewed by the Trip.ovh planning team at COD Solutions Oy · Last reviewed Apr 17, 2026 · Editorial standards

Drive Time

5h 17m

Distance

273.2 mi

440 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$43

one way

EV Charging

Unknown

Best Time to Leave

Save up to 40 min
4 AM
5h 4m ★
6 AM
5h 17m
8 AM
5h 44m
10 AM
5h 27m
12 PM
5h 24m
3 PM
5h 28m
5 PM
5h 43m
8 PM
5h 9m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown Clemson, SC, SC

Clemson, SC

R9 Media Photo Collective

Downtown Bluffton, SC, SC

Bluffton, SC

Connor Scott McManus

Trip Overview

The drive from Clemson, SC to Bluffton, SC covers 273.2 miles and takes about 5h 17m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on Tiger Boulevard, Calhoun Memorial Highway, Highway 153 for much of the mileage, and the overall profile is turn-heavy local drive. At current regular gas prices, budget about $42.72 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

136.6 miles from Clemson, SC

A natural place for your longest stop of the day , about 2h 38m into the drive .

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 5h 17m. Total distance: 273.2 miles.

Family Friendly

Moderate complexity with 1 natural rest stops along the way.

Solo Traveler

5h 17m drive, comfortable solo distance.

First-Time Driver

Mostly highway driving (0%). Straightforward navigation.

Scenic Drive

Turn-heavy local drive route profile.

Drive Character

Expect a 5h 17m drive with frequent turns across 273.2 miles of local and secondary roads.

This route has more turning and local-road decision points than a simple highway run.
There are about 26 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Tiger Boulevard is one of the defining roads on this drive.

How Hard Is This Drive?

Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. There are only a few real navigation decisions along the way.

Driving Effort 3/10

Easy - simple navigation with a manageable amount of wheel time

Balances navigation complexity with total wheel time.

This is a straightforward 5h 17m drive. You will face about 0 decision points, but nothing that requires special attention if you follow navigation.

Where does it get tricky?

This route does not have any notably tricky sections. Most of the drive from Clemson, SC to Bluffton, SC is straightforward, with well-signed roads and simple exits.

Main Roads

Road Distance Duration
Tiger Boulevard
Calhoun Memorial Highway
Highway 153
Southern Connector
I 385 South
Golden Strip Freeway
Charleston
I 95 South

Some road-level metrics are being recalculated.

Longest stretch: Tiger Boulevard — detailed segment metrics are refreshing.

Turn-by-Turn Driving Directions

Step-by-step road directions between Clemson, SC and Bluffton, SC.

1

Start on College Avenue

0.6 mi · 1 min · College Avenue
2

Turn right onto Tiger Boulevard

2.7 mi · 4 min · Tiger Boulevard
3

Continue on Calhoun Memorial Highway

18 mi · 23 min · Calhoun Memorial Highway
4

Take the exit slight right

0.3 mi · 42 sec
5

Keep slight right

0.1 mi · 21 sec
6

Merge slight left onto Highway 153

6.3 mi · 10 min · Highway 153
7

Take the exit right

0.4 mi · 48 sec
8

Merge slight left onto Southern Connector

11 mi · 11 min · Southern Connector
9

Take the exit slight right toward I 385 South: Columbia

0.6 mi · 1 min · I 385 South: Columbia
10

Merge slight right

0.2 mi · 14 sec
11

Merge slight left onto Golden Strip Freeway

30 mi · 32 min · Golden Strip Freeway
12

Merge slight left

56 mi · 1 hr 1 min
13

Keep slight right to continue on Charleston

60 mi · 1 hr 6 min · Charleston
14

Take the exit slight right toward I 95 South: Savannah

0.9 mi · 1 min · I 95 South: Savannah
15

Merge slight left

57 mi · 1 hr
16

Take the exit slight right toward SC 462: Coosawhatchie

0.3 mi · 37 sec · SC 462: Coosawhatchie
17

Turn left onto Coosaw Scenic Drive

9.6 mi · 13 min · Coosaw Scenic Drive
18

Continue on Lowcountry Drive

7.9 mi · 10 min · Lowcountry Drive
19

Turn right onto Okatie Highway

4.2 mi · 4 min · Okatie Highway
20

Take the exit slight right

0.3 mi · 37 sec
21

Merge slight left onto Fording Island Road

5.8 mi · 6 min · Fording Island Road
22

Turn right onto Bluffton Road

0.8 mi · 1 min · Bluffton Road
23

Enter the roundabout and take exit 2 toward Bluffton Road

171 ft · 4 sec · Bluffton Road
24

Exit the roundabout onto Bluffton Road

0.9 mi · 1 min · Bluffton Road
25

Turn left onto Bruin Road

89 ft · 2 sec · Bruin Road
26

Arrive at your destination

Trip Plan

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 136.6 miles from Clemson, SC, or about 2h 38m into the drive.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 60 miles or 1h 9m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 136.6 miles or 2h 38m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 4h 20m

Traffic, exits, and arrival timing usually matter more near Bluffton, SC than in the middle of the route.

Before You Leave

+

Open the route before leaving Clemson, SC so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Clemson, SC

This is one driving day of about 273.2 miles and 5h 17m.

Your first comfortable stop window is around 60 miles from Clemson, SC.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 136.6 mi from Clemson, SC · 2h 38m into the drive

city in Lexington County, South Carolina, United States of America

Mid-route town

Meal stop

West Columbia, SC

137 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Greenville, SC

Fuel and coffee

A short stop after about 60 miles helps settle the day before fatigue starts building.

West Columbia, SC

Meal break

The midpoint is around 136.6 miles from Clemson, SC, which is a good place for a longer meal and fuel stop.

Arriving in Bluffton, SC

The final approach into Bluffton, SC usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Bluffton, SC.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$42.72 one way

$85.44 round trip

$3.97/gal 25.4 MPG avg 96 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.34 $46.71 $93.43
premium $4.70 $50.56 $101.13
diesel $5.61 $60.32 $120.64

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$43

Meals

$25–$50

Total

$68–$93

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 95.6 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $29 in charging · 1 stop · 67% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 82 1 $28.69 $13.11
Efficient EV 68.3 0 $23.90 $10.93
EV Truck/SUV 109.3 1 $38.25 $17.48

Gas CO2

96 kg

EV CO2

32 kg (67% less)

Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 15, 2026

Origin

Clemson, SC

Late night in Clemson on Friday

Local time

5:18 AM

EDT

Current temp

49°F

Unavailable

Live forecast

Destination

Bluffton, SC

Late night in Bluffton on Friday

Local time

5:18 AM

EDT

Current temp

57°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

8 degrees warmer at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

5h 17m on the road

An early start around 7-8 AM gets you there with plenty of daylight left.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Clemson, SC to Bluffton, SC covers 273.2 miles and takes about 5h 17m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.

The main roads are Tiger Boulevard, Calhoun Memorial Highway, Highway 153. Expect a mix of highway and local road driving.

This is a comfortable same-day trip.

The midpoint is about 136.6 miles from Clemson, SC. Look for rest areas, gas stations, or food options near the halfway mark.

At current regular gas prices, expect to spend about $42.72 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.

An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.

Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

This is a straightforward 5h 17m drive. You will face about 0 decision points, but nothing that requires special attention if you follow navigation.

This route does not have any notably tricky sections. Most of the drive from Clemson, SC to Bluffton, SC is straightforward, with well-signed roads and simple exits.

The route from Clemson, SC to Bluffton, SC does not surface many named destination signs beyond the main corridor.

How this page is built

Compiled and maintained by the Trip.ovh planning team at COD Solutions Oy (Helsinki). Each route is built from authoritative open government and mapping datasets rather than crowdsourced reviews. Distances and geometry come from OSRM over OpenStreetMap. Fuel cost uses EIA weekly regional averages. Pages are published only after passing our data-quality checks; our methodology page documents refresh cadence, editorial standards, and known limitations.

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