Drive Time
4h 45m
Distance
281.1 mi
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$44
one way
The drive from Clemson, SC to Myrtle Beach, SC covers 281.1 miles and takes about 4h 45m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on Tiger Boulevard, Calhoun Memorial Highway, Highway 153 for much of the mileage, and the overall profile is turn-heavy local drive. At current regular gas prices, budget about $43.84 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
140.5 miles from Clemson, SC
A natural place for your longest stop of the day , about 2h 22m into the drive .
Expect a 4h 45m drive with frequent turns across 281.1 miles of local and secondary roads.
| Road | Distance | Duration |
|---|---|---|
| Tiger Boulevard | Unavailable | Refreshing |
| Calhoun Memorial Highway | Unavailable | Refreshing |
| Highway 153 | Unavailable | Refreshing |
| Southern Connector | Unavailable | Refreshing |
| I 385 South | Unavailable | Refreshing |
| Golden Strip Freeway | Unavailable | Refreshing |
| I 20 East | Unavailable | Refreshing |
| West Evans Street | Unavailable | Refreshing |
Per-road distance and duration are being refreshed from OSRM for this route.
Step-by-step road directions between Clemson, SC and Myrtle Beach, SC.
Start on College Avenue
Turn right onto Tiger Boulevard
Continue on Calhoun Memorial Highway
Take the exit slight right
Keep slight right
Merge slight left onto Highway 153
Take the exit right
Merge slight left onto Southern Connector
Take the exit slight right toward I 385 South: Columbia
Merge slight right
Merge slight left onto Golden Strip Freeway
Merge slight left
Take the exit slight right toward I 20 East: Florence
Merge slight left
Turn left onto West Evans Street
Turn right onto Warley Street
Turn left onto West Cheves Street
At the end of the road, turn left onto East Palmetto Street
Continue straight
Continue straight
Turn straight
Turn slight right onto 8th Avenue North
Turn right onto North Kings Highway
Turn left onto 5th Avenue North
Turn right
Arrive at your destination
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 21m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 140.5 miles or 2h 22m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 54m
Traffic, exits, and arrival timing usually matter more near Myrtle Beach, SC than in the middle of the route.
Open the route before leaving Clemson, SC so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Clemson, SC
This is one driving day of about 281.1 miles and 4h 45m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 140.5 mi from Clemson, SC · 2h 22m into the drive
Mid-route town
Meal stop
141 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 80 miles helps settle the day before fatigue starts building.
The midpoint is around 140.5 miles from Clemson, SC, which is a good place for a longer meal and fuel stop.
The final approach into Myrtle Beach, SC usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Myrtle Beach, SC.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$43.84 one way
$87.67 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.43 | $49.02 | $98.03 |
| premium | $4.78 | $52.88 | $105.76 |
| diesel | $5.62 | $62.24 | $124.48 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$44
Meals
$25–$50
Total
$69–$94
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 98.4 kg one way.
Driving Electric?
About $30 in charging · 1 stop · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 84.3 | 1 | $29.52 | $13.49 |
| Efficient EV | 70.3 | 0 | $24.60 | $11.24 |
| EV Truck/SUV | 112.4 | 1 | $39.35 | $17.99 |
Gas CO2
98 kg
EV CO2
33 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive. If you're planning ahead, check the forecast closer to your travel date.
Origin
Morning in Clemson on Saturday
Local time
6:41 AM
EDT
Current temp
64°F
Forecast unavailable right now
Destination
Morning in Myrtle Beach on Saturday
Local time
6:41 AM
EDT
Current temp
65°F
Forecast unavailable right now
Along the Route
65°F
Charlotte, NC
141 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
Explore more options from Clemson, SC or browse trips ending in Myrtle Beach, SC.
Looking for more statewide routes? Browse SC road trips.
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