The drive from Dubuque, IA to Carlisle, IA covers 193.6 miles and takes about 3h 51m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on US 151, Lincoln Highway, Marshalltown Boulevard for much of the mileage,
and the overall profile is mixed drive.
The longest uninterrupted segment is about 58.1 miles on US 151.
At current regular gas prices, budget about $30.27 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
96.8 miles from Dubuque, IA
A natural place for your longest stop of the day
, about 1h 55m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 3h 51m. Total distance: 193.6 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
The drive from Dubuque, IA to Carlisle, IA covers 193.6 miles and takes about 3h 51m, using a mix of highways and local roads.
Expect a mix of faster highway mileage and slower local approaches near the beginning or end.
There are about 20 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
US 151 is the longest continuous segment at about 58.1 miles.
How Hard Is This Drive?
This route mixes highway mileage with some local-road sections near the start or finish. There are only a few real navigation decisions along the way. The trickiest moment comes around 0.2 miles in.
Driving Effort4/10
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
This is a straightforward 3h 51m drive. You will face about 11 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
The main spots that need attention: at 0.2 miles: Multiple destination signs - pick the right one; at 64.1 miles (IA 100): Navigation decision point; at 79.3 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one.
Critical Maneuvers
5 of 11 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
6
0.2 mi into trip|~0m in
Take the ramp toward US 61 South, US 151 South
Multiple destination signs - pick the right one
Exit 189A
Toward US 61 South, US 151 South
4
64.1 mi into trip|~1h 16m in|IA 100
Turn right onto IA 100
Navigation decision point
5
79.3 mi into trip|~1h 35m in
Take the exit toward US 30 West, US 218 North: Tama, Marshalltown
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Toward US 30 West, US 218 North: Tama, Marshall...
5
144.1 mi into trip|~2h 50m in
Take the exit toward IA 330: Melbourne, Des Moines
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Toward IA 330: Melbourne, Des Moines
5
180.6 mi into trip|~3h 34m in
Turn left
Lane positioning matters here
Use the straight / left lanes.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Dubuque, IA and Carlisle, IA, road signs point toward Marshalltown and Des Moines.
Marshalltown
79.3 mi in|~1h 35m
Des Moines
144.1 mi in|~2h 50m
Main Roads
Road
Distance
Duration
US 151
58.1 mi
1h 7m
Lincoln Highway
37.3 mi
43m
Marshalltown Boulevard
33.7 mi
39m
73rd Street
24.4 mi
28m
IA 100
15.2 mi
18m
Military Order of the Purple Heart Highway
9.6 mi
11m
US 61
5.6 mi
7m
16th Avenue Southwest
2.4 mi
2m
Longest stretch:
US 151
— 58.1 mi, about 1h 7m
Turn-by-Turn Driving Directions
Step-by-step road directions between Dubuque, IA and Carlisle, IA.
1
Start on Central Avenue
0.2 mi·33 sec·Central Avenue
2
Take the ramp
0.2 mi·28 sec
Exit 189AToward US 61 South, US 151 South
3
Continue on US 61; US 151
5.6 mi·7 min·US 61; US 151
4
Take the exit onto US 151
57 mi·1 hr 6 min·US 151
5
Turn left onto US 151; IA 13
1.1 mi·1 min·US 151; IA 13
6
Turn right onto IA 100
15 mi·18 min·IA 100
7
Take the exit
0.7 mi·1 min
Toward US 30 West, US 218 North: Tama, Marshalltown
8
Merge onto US 30; US 218
2.4 mi·2 min·16th Avenue Southwest
9
Continue on US 30; US 218
24 mi·28 min·73rd Street
10
Continue on US 30
37 mi·43 min·Lincoln Highway
11
Take the exit
0.3 mi·46 sec
Toward IA 330: Melbourne, Des Moines
12
Turn left onto IA 330
34 mi·39 min·Marshalltown Boulevard
13
Continue on US 65; IA 330
1.2 mi·1 min·Northeast Hubbell Avenue
14
Continue on US 6
1.3 mi·2 min·Hubbell Avenue
15
Turn left
0.5 mi·1 min
Use the straight / left lanes.
16
Merge onto US 65
9.6 mi·11 min·Military Order of the Purple Heart Highway
17
Take the exit
0.6 mi·1 min
Toward IA 5 South: Carlisle
18
Continue on IA 5
1.9 mi·2 min·IA 5
19
Turn left onto South 5th Street
0.3 mi·1 min·South 5th Street
20
Arrive at destination
North 5th Street
Trip Plan
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 96.8 miles from Dubuque, IA, or about 1h 55m into the drive.
The longest continuous stretch on this route runs about 58.1 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 43 miles or 51m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 96.8 miles or 1h 55m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 8m
Traffic, exits, and arrival timing usually matter more near Carlisle, IA than in the middle of the route.
Before You Leave
+
Open the route before leaving Dubuque, IA so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Dubuque, IA
This is one driving day of about 193.6 miles and 3h 51m.
Your first comfortable stop window is around 43 miles from Dubuque, IA.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on US 151 for about 58.1 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 96.8 mi from Dubuque, IA
· 1h 55m into the drive
Place data sourced from public business listings. Hours and availability may vary.
Fuel & Cost
Regular Gas
$30.27 one way
$60.53 round trip
$3.97/gal25.4 MPG avg68 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.36
$33.23
$66.46
premium
$4.89
$37.26
$74.51
diesel
$5.61
$42.74
$85.49
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$30
Meals
$25–$50
Total
$55–$80
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 67.7 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $20 in charging
· 0 stops
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
58.1
0
$20.33
$9.29
Efficient EV
48.4
0
$16.94
$7.74
EV Truck/SUV
77.4
0
$27.10
$12.39
Gas CO2
68 kg
EV CO2
23 kg (66% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 16, 2026
Origin
Dubuque, IA
Late night
in Dubuque on Friday
Local time
1:10 AM
CDT
Current temp
47°F
Unavailable
Live forecast
Destination
Carlisle, IA
Late night
in Carlisle on Friday
Local time
1:10 AM
CDT
Current temp
74°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
27 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
3h 51m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Dubuque, IA to Carlisle, IA covers 193.6 miles and takes about 3h 51m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are US 151, Lincoln Highway, Marshalltown Boulevard. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 96.8 miles from Dubuque, IA. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $30.27 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. A short stop every 2 to 3 hours is enough for this drive.
This is a straightforward 3h 51m drive. You will face about 11 decision points, but nothing that requires special attention if you follow navigation.
The main spots that need attention: at 0.2 miles: Multiple destination signs - pick the right one; at 64.1 miles (IA 100): Navigation decision point; at 79.3 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one.
Between Dubuque, IA and Carlisle, IA, road signs point toward Marshalltown and Des Moines.
