The drive from Enfield, ME to Sanford, ME covers 199.9 miles and takes about 3h 50m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on I 95, I 295, Maine Turnpike for much of the mileage,
and the overall profile is highway-focused drive.
The longest uninterrupted segment is about 112.9 miles on I 95.
At current regular gas prices, budget about $32.18 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
100 miles from Enfield, ME
A natural place for your longest stop of the day
, about 1h 52m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 3h 50m. Total distance: 199.9 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
3h 50m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (89%). Some complex stretches to watch for.
Drive Character
This is a 3h 50m highway drive covering 199.9 miles, with most of the trip on I 95 and I 295. The longest continuous stretch is about 112.9 miles on I 95.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 21 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
I 95 is the longest continuous segment at about 112.9 miles.
How Hard Is This Drive?
This is a straightforward highway drive that stays mostly on I 95 and I 295. You will hit about 10 points where you need to pay attention to lane position or signs. The trickiest moment comes around 4.7 miles in near ME 6; ME 155 / LaGrange Road.
Driving Effort5/10
Moderate - straightforward overall, but long enough or busy enough to require pacing
Balances navigation complexity with total wheel time.
This drive requires moderate attention. Across 199.9 miles you will encounter 10 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: at 4.7 miles (ME 6; ME 155 / LaGrange Road): Roundabout - know your exit number before entering; at 5.7 miles: Navigation decision point; at 119 miles (I 295): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
Critical Maneuvers
5 of 10 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
5
4.7 mi into trip|~8m in|ME 6; ME 155 / LaGrange Road
Enter roundabout onto ME 6; ME 155 / LaGrange Road
Roundabout - know your exit number before entering
4
5.7 mi into trip|~10m in
Take the ramp
Navigation decision point
9
119 mi into trip|~2h 12m in|I 295
Keep slight right at fork onto I 295 toward I 295 South, ME 9, ME 126: Gardiner, Brunswick
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight lane.
Exit 103
Toward I 295 South, ME 9, ME 126: Gardiner, Bru...
4
169.5 mi into trip|~3h 11m in|I 295
Keep slight left at fork onto I 295
Highway fork - watch signs carefully
5
183.8 mi into trip|~3h 27m in
Take the exit toward ME 111: Biddeford
Exit ramp - move to the correct lane early
Exit 32
Toward ME 111: Biddeford
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Enfield, ME to Sanford, ME, road signs begin pointing toward Brunswick along the way.
Brunswick
119 mi in|~2h 12m|via I 295
Main Roads
Road
Distance
Duration
I 95
112.9 mi
2h 1m
I 295
53.2 mi
1h 2m
Maine Turnpike
11.6 mi
12m
Alfred Road
8.2 mi
9m
Hammett Road
3.7 mi
6m
Sanford Road
2.4 mi
3m
Biddeford Road
1.8 mi
2m
Alfred Street
1.4 mi
1m
Longest stretch:
I 95
— 112.9 mi, about 2h 1m
Turn-by-Turn Driving Directions
Step-by-step road directions between Enfield, ME and Sanford, ME.
1
Start on ME 155
3.7 mi·6 min·Hammett Road
2
Continue on ME 6; ME 116; ME 155
0.5 mi·52 sec·Bridge Street
3
Continue on ME 6; ME 116; ME 155
0.4 mi·46 sec·Bridge Road
4
Continue on ME 6; ME 155
359 ft·8 sec·Coffin Street
5
Enter roundabout onto ME 6; ME 155
187 ft·3 sec·LaGrange Road
6
Continue on ME 6; ME 155
1.0 mi·1 min·LaGrange Road
7
Take the ramp
0.4 mi·47 sec
8
Merge onto I 95
113 mi·2 hr 1 min·I 95
9
Keep slight right at fork onto I 295
51 mi·58 min·I 295
Exit 103Toward I 295 South, ME 9, ME 126: Gardiner, BrunswickUse the straight lane.
10
Keep slight left at fork onto I 295
2.6 mi·3 min·I 295
11
Merge onto I 95
12 mi·12 min·Maine Turnpike
12
Take the exit
0.7 mi·1 min
Exit 32Toward ME 111: Biddeford
13
Turn right onto ME 111
1.4 mi·1 min·Alfred Street
14
Continue on ME 111
8.2 mi·9 min·Alfred Road
15
Continue on ME 111
1.8 mi·2 min·Biddeford Road
16
Continue on US 202; ME 4A
2.4 mi·3 min·Sanford Road
Use the left / straight / right lanes.
17
Continue on US 202; ME 4A
1.2 mi·3 min·Cottage Street
18
Turn left onto River Street
0.2 mi·26 sec·River Street
19
Continue on Washington Street
0.1 mi·25 sec·Washington Street
20
Turn left
89 ft·6 sec
21
Arrive at destination
Trip Plan
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 100 miles from Enfield, ME, or about 1h 52m into the drive.
The longest continuous stretch on this route runs about 112.9 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 44 miles or 51m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 100 miles or 1h 52m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 4m
Traffic, exits, and arrival timing usually matter more near Sanford, ME than in the middle of the route.
Before You Leave
+
Open the route before leaving Enfield, ME so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Enfield, ME
This is one driving day of about 199.9 miles and 3h 50m.
Your first comfortable stop window is around 44 miles from Enfield, ME.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 95 for about 112.9 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 100 mi from Enfield, ME
· 1h 52m into the drive
Place data sourced from public business listings. Hours and availability may vary.
National Parks Near This Route
Worth a detour if your schedule allows.
Frances Perkins National Monument
National Monument
Known as the first woman to hold a presidential cabinet position and the “Woman behind the New Deal,” Frances Perkins championed many labor rights that Americans enjoy today, including safety standard...
17 mi from route
~42 min detour
Free
near mile 131
Park data from the National Park Service API. Alerts update every 2 hours.
Fuel & Cost
Regular Gas
$32.18 one way
$64.36 round trip
$4.09/gal25.4 MPG avg70 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.50
$35.41
$70.81
premium
$4.86
$38.28
$76.56
diesel
$5.61
$44.14
$88.27
Estimated Tolls: $0.70
Maine Turnpike
(11.6 mi)$0.70
Toll estimates based on average 2024-2025 rates. EZ-Pass/SunPass discounts may lower the actual cost.
Estimated Trip Cost (one way, 1 person)
Fuel
$32
Tolls
$1
Meals
$25–$50
Total
$58–$83
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 69.9 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $21 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
60
0
$20.99
$9.60
Efficient EV
50
0
$17.49
$8.00
EV Truck/SUV
80
0
$27.99
$12.79
Gas CO2
70 kg
EV CO2
23 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Enfield, ME
Night
in Enfield on Friday
Local time
9:10 PM
EDT
Current temp
34°F
Unavailable
Live forecast
Destination
Sanford, ME
Night
in Sanford on Friday
Local time
9:10 PM
EDT
Current temp
51°F
Unavailable
Live forecast
46°F
Brunswick, ME
100 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
17 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
3h 50m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Enfield, ME to Sanford, ME covers 199.9 miles and takes about 3h 50m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are I 95, I 295, Maine Turnpike. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 100 miles from Enfield, ME. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $32.18 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. A short stop every 2 to 3 hours is enough for this drive.
This drive requires moderate attention. Across 199.9 miles you will encounter 10 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
The main spots that need attention: at 4.7 miles (ME 6; ME 155 / LaGrange Road): Roundabout - know your exit number before entering; at 5.7 miles: Navigation decision point; at 119 miles (I 295): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
On the drive from Enfield, ME to Sanford, ME, road signs begin pointing toward Brunswick along the way.
Yes. Nearby national parks include Frances Perkins National Monument.
How this page is built
Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.
