The drive from Florence, SC to Varnville, SC covers 136 miles and takes about 2h 47m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on I 95, Sniders Highway, Walterboro Highway for much of the mileage,
and the overall profile is highway-focused drive.
The longest uninterrupted segment is about 106.7 miles on I 95.
At current regular gas prices, budget about $21.27 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
68 miles from Florence, SC
A natural place for your longest stop of the day
, about 1h 17m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 2h 47m. Total distance: 136 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
This is a 2h 47m highway drive covering 136 miles, with most of the trip on I 95 and Sniders Highway. The longest continuous stretch is about 106.7 miles on I 95.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 16 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
I 95 is the longest continuous segment at about 106.7 miles.
How Hard Is This Drive?
This is a straightforward highway drive that stays mostly on I 95 and Sniders Highway. Navigation is very simple - set it and forget it for most of the drive. The trickiest moment comes early in the drive.
Driving Effort2/10
Very easy - short and simple to drive
Balances navigation complexity with total wheel time.
The drive from Florence, SC to Varnville, SC is easy. At 2h 47m with 79% highway, most drivers will find it relaxed and low-stress.
Where does it get tricky?
The main spots that need attention: near the start: Navigation decision point; near the start (East Cheves Street): Navigation decision point; at 5.5 miles (I 95): Merge point - match speed before joining. Lane positioning matters here.
Critical Maneuvers
5 of 10 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
5
0 mi into trip|~0m in
Turn left
Navigation decision point
5
0 mi into trip|~0m in|East Cheves Street
At end of road, turn left onto East Cheves Street
Navigation decision point
5
5.5 mi into trip|~10m in|I 95
Merge onto I 95
Merge point - match speed before joining. Lane positioning matters here
Use the straight / slight right lanes.
5
112.1 mi into trip|~2h 5m in
Take the exit toward SC 63: Varnville, Hampton
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Toward SC 63: Varnville, Hampton
5
136 mi into trip|~2h 47m in|North Palm Street
Turn right onto North Palm Street
Navigation decision point
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Florence, SC to Varnville, SC, road signs begin pointing toward Hampton along the way.
Hampton
112.1 mi in|~2h 5m
Main Roads
Road
Distance
Duration
I 95
106.7 mi
1h 54m
Sniders Highway
16.7 mi
29m
Walterboro Highway
5.8 mi
10m
West Evans Street
2.4 mi
4m
West David H McLeod Boulevard
1.5 mi
2m
Main Street
0.9 mi
1m
East Cheves Street
0.7 mi
1m
J Strom Thurmond Freeway
0.5 mi
<1m
Longest stretch:
I 95
— 106.7 mi, about 1h 54m
Turn-by-Turn Driving Directions
Step-by-step road directions between Florence, SC and Varnville, SC.
1
Start on this road
50 ft·8 sec·this road
2
Turn left
133 ft·15 sec
3
At end of road, turn left onto East Cheves Street
0.7 mi·1 min·East Cheves Street
4
Turn right onto Warley Street
0.1 mi·18 sec·Warley Street
5
Turn left onto S-21-31
2.4 mi·4 min·West Evans Street
6
Turn right onto I 20 Bus
1.5 mi·2 min·West David H McLeod Boulevard
7
Continue on I 20 Bus
0.5 mi·53 sec·J Strom Thurmond Freeway
8
Take the exit
0.3 mi·36 sec
Toward I 95 South: Savannah
9
Merge onto I 95
107 mi·1 hr 54 min·I 95
Use the straight / slight right lanes.
10
Take the exit
0.4 mi·45 sec
Toward SC 63: Varnville, Hampton
11
Turn slight right onto SC 63
17 mi·29 min·Sniders Highway
12
Continue on SC 63
5.8 mi·10 min·Walterboro Highway
13
Continue on SC 63
0.9 mi·1 min·Main Street
14
Turn left onto Wood Street
248 ft·12 sec·Wood Street
15
Turn right onto North Palm Street
185 ft·8 sec·North Palm Street
16
Arrive at destination
North Palm Street
Trip Plan
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 68 miles from Florence, SC, or about 1h 17m into the drive.
The longest continuous stretch on this route runs about 106.7 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 30 miles or 37m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 68 miles or 1h 17m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 4m
Traffic, exits, and arrival timing usually matter more near Varnville, SC than in the middle of the route.
Before You Leave
+
Open the route before leaving Florence, SC so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Florence, SC
This is one driving day of about 136 miles and 2h 47m.
Your first comfortable stop window is around 30 miles from Florence, SC.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 95 for about 106.7 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 68 mi from Florence, SC
· 1h 17m into the drive
The midpoint is around 68 miles from Florence, SC, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel check
Top up before I 95 if your tank is already low. That segment runs about 106.7 miles.
Arriving in Varnville, SC
The final approach into Varnville, SC usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Varnville, SC.
After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
National Parks Near This Route
Worth a detour if your schedule allows.
Congaree National Park
National Park
Astonishing biodiversity exists in Congaree National Park, the largest intact expanse of old growth bottomland hardwood forest remaining in the southeastern United States. Waters from the Congaree and...
Park data from the National Park Service API. Alerts update every 2 hours.
Fuel & Cost
Regular Gas
$21.27 one way
$42.53 round trip
$3.97/gal25.4 MPG avg48 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.34
$23.25
$46.51
premium
$4.70
$25.17
$50.34
diesel
$5.61
$30.03
$60.05
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$21
Meals
$25–$50
Total
$46–$71
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 47.6 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $14 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
40.8
0
$14.28
$6.53
Efficient EV
34
0
$11.90
$5.44
EV Truck/SUV
54.4
0
$19.04
$8.70
Gas CO2
48 kg
EV CO2
16 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 18, 2026
Origin
Florence, SC
Morning
in Florence on Saturday
Local time
6:31 AM
EDT
Current temp
62°F
Partly Cloudy
SW 2 mph0% chanceLive forecast
Destination
Varnville, SC
Morning
in Varnville on Saturday
Local time
6:31 AM
EDT
Current temp
49°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
13 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
2h 47m on the road
The weather snapshot is not static. If you are leaving later, give both cities one more quick forecast check before departure.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Florence, SC to Varnville, SC covers 136 miles and takes about 2h 47m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are I 95, Sniders Highway, Walterboro Highway. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 68 miles from Florence, SC. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $21.27 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Leave by 9 AM and you'll arrive before lunch. Even a 4 PM departure gets you there before dark in summer.
Plan about 1 meaningful break for fuel, food, or rest. A short stop every 2 to 3 hours is enough for this drive.
The drive from Florence, SC to Varnville, SC is easy. At 2h 47m with 79% highway, most drivers will find it relaxed and low-stress.
The main spots that need attention: near the start: Navigation decision point; near the start (East Cheves Street): Navigation decision point; at 5.5 miles (I 95): Merge point - match speed before joining. Lane positioning matters here.
On the drive from Florence, SC to Varnville, SC, road signs begin pointing toward Hampton along the way.
How this page is built
Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.
