Drive Time
6h 26m
Distance
313.4 mi
504 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$48
one way
Photo: Shaun Iwasawa
If you are planning a trip from Fulton to Oxford, Mississippi, expect a journey covering 313.4 miles that typically takes about 6 hours and 26 minutes to complete. Because this is a highway-focused drive, it is best suited for a single day of travel if you are comfortable spending significant time behind the wheel. You should budget approximately $48 for fuel to cover the distance. Navigating through the Southeast, you will rely primarily on MS 25, I-55, and US Highway 45 Alternate to reach your destination. While the trip is manageable in one go, consider your own endurance levels before deciding if you need an overnight stay to break up the drive.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
156.7 miles from Fulton, MS
A natural place for your longest stop of the day , about 3h 8m into the drive .
This route is heavily centered on high-speed travel, with highways accounting for 89% of the total distance. You will experience a mix of road types, but the longest uninterrupted stretch—a 136.2-mile run along MS 25—defines the core of the experience. Expect a consistent pace as you transition between these major thoroughfares. The drive feels efficient and direct, moving you steadily across the state. Because the majority of your time is spent on major roads, you can anticipate a fairly uniform experience behind the wheel for the duration of the journey.
This is a straightforward highway drive that stays mostly on MS 25 and I 55. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 17.3 miles in.
High effort - long or complex enough to need steady focus all day
This is a demanding drive. With 22 significant decision points across 313.4 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 17.3 miles: Highway fork - watch signs carefully; at 22.8 miles: Lane positioning matters here. Multiple destination signs - pick the right one; at 87.2 miles (MS 25): Exit ramp - move to the correct lane early. Lane positioning matters here.
These are the spots where you need to pay the most attention. Preview them before you drive.
Keep slight left at fork
Highway fork - watch signs carefully
Turn left toward US 45 South, MS 6 West: Columbus, Pontotoc
Lane positioning matters here. Multiple destination signs - pick the right one
Take the exit onto MS 25 toward MS 25 South: Louisville
Exit ramp - move to the correct lane early. Lane positioning matters here
Keep slight left at fork onto I 55 toward I 55 South: McComb, New Orleans
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Keep slight right at fork toward US 84: South Brookhaven, Natchez
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Between Fulton, MS and Oxford, MS, road signs point toward Pontotoc, New Orleans and Natchez.
Pontotoc
New Orleans
Natchez
| Road | Distance | Duration |
|---|---|---|
| MS 25 | 136.2 mi | 2h 36m |
| I 55 | 59.9 mi | 1h 5m |
| US Highway 45 Alternate | 35.7 mi | 43m |
| US 84 | 22.7 mi | 26m |
| I 22 | 14.2 mi | 15m |
| Martin Luther King Drive | 7.7 mi | 8m |
| US 45 ALT | 7.2 mi | 8m |
| Gloster Road | 6.5 mi | 15m |
Step-by-step road directions between Fulton, MS and Oxford, MS.
Start on North Cummings Street
Turn left onto MS 178
Turn right onto South Adams Street
Take the ramp
Merge onto I 22; US 78
Take the exit
Keep slight left at fork
Turn left
Turn straight onto CR 931
Continue on North Eason Boulevard
Turn left
Merge onto US 45; MS 6
Continue on US 45; US 278
Continue on US 45 ALT
Continue on US 45 ALT
Continue on US 45 ALT
Continue on US 45 ALT
Continue on US 45 ALT
Continue on US 45 ALT
Take the exit onto MS 25
Take the exit onto MS 25
Continue on MS 25
Keep slight right at fork onto MS 25
Take the exit onto MS 25
Take the exit
Merge onto I 55
Keep slight left at fork onto I 55
Take the exit
Keep slight right at fork
Merge onto US 84
Turn left onto MS 184
Turn left onto US 98
Turn right onto Yap 3 Road
Continue on Gloster Road
At end of road, turn right onto Gloster Road
Continue on Oxford-Meadville Road
Arrive at destination
To make the most of this 313.4-mile trek, aim for an early morning departure to avoid potential traffic delays on the interstate portions. Since you are only planning for one major stop, choose a location that aligns with your halfway point to keep your momentum steady. Keep a close eye on your fuel gauge during the 136.2-mile stretch on MS 25, as finding a station may be less convenient than on the busier I-55 sections. Having the flexibility to complete this in one day is a major advantage, but do not hesitate to build in extra time if you encounter unexpected road work. Planning your single stop in advance will help you maintain your estimated 6-hour and 26-minute arrival time.
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 39m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 156.7 miles or 3h 8m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 5h 1m
Traffic, exits, and arrival timing usually matter more near Oxford, MS than in the middle of the route.
Open the route before leaving Fulton, MS so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Fulton, MS
This is one driving day of about 313.4 miles and 6h 26m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 156.7 mi from Fulton, MS · 3h 8m into the drive
Mid-route town
Meal stop
157 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 80 miles helps settle the day before fatigue starts building.
The midpoint is around 156.7 miles from Fulton, MS, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before MS 25 if your tank is already low. That segment runs about 136.2 miles.
The final approach into Oxford, MS usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Oxford, MS.
After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$47.91 one way
$95.82 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.26 | $52.55 | $105.10 |
| premium | $4.61 | $56.88 | $113.76 |
| diesel | $5.64 | $69.63 | $139.25 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$48
Meals
$25–$50
Total
$73–$98
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 109.7 kg one way. Prices: EIA weekly data, 2026-04-06.
Driving Electric?
About $33 in charging · 1 stop · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 94 | 1 | $32.91 | $15.04 |
| Efficient EV | 78.4 | 0 | $27.42 | $12.54 |
| EV Truck/SUV | 125.4 | 1 | $43.88 | $20.06 |
Gas CO2
110 kg
EV CO2
37 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive. If you're planning ahead, check the forecast closer to your travel date.
Origin
Late night in Fulton on Sunday
Local time
2:33 AM
CDT
Current temp
65°F
Forecast unavailable right now
Destination
Late night in Oxford on Sunday
Local time
2:33 AM
CDT
Current temp
64°F
Forecast unavailable right now
Along the Route
85°F
Magee, MS
157 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
Start early — leave by 6-7 AM to arrive at a reasonable hour.
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