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Trip from Greenfield, MO to St. Louis, MO

Drive Time

4h 3m

Distance

253.5 mi

408 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$39

one way

Trip Overview

The drive from Greenfield, MO to St. Louis, MO covers 253.5 miles and takes about 4h 3m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on Talbutt Street, Lilly Street, N Grand Street for much of the mileage, and the overall profile is turn-heavy local drive. At current regular gas prices, budget about $38.50 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

126.8 miles from Greenfield, MO

A natural place for your longest stop of the day , about 2h 1m into the drive .

Drive Character

Expect a 4h 3m drive with frequent turns across 253.5 miles of local and secondary roads.

This route has more turning and local-road decision points than a simple highway run.
There are about 20 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Talbutt Street is one of the defining roads on this drive.

How Hard Is This Drive?

Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. There are only a few real navigation decisions along the way.

Route Complexity 3/10

Easy - simple navigation with a manageable amount of wheel time

This is a straightforward 4h 3m drive. You will face about 0 decision points, but nothing that requires special attention if you follow navigation.

Where does it get tricky?

This route does not have any notably tricky sections. Most of the drive from Greenfield, MO to St. Louis, MO is straightforward, with well-signed roads and simple exits.

Main Roads

Road Distance Duration
Talbutt Street Unavailable Refreshing
Lilly Street Unavailable Refreshing
N Grand Street Unavailable Refreshing
the route Unavailable Refreshing
Payne Stewart Highway Unavailable Refreshing
Police Officer Ernest M Unavailable Refreshing
Police Officer Robert Stanze Memorial Highway Unavailable Refreshing
Officer Michael Barwick Memorial Highway Unavailable Refreshing

Per-road distance and duration are being refreshed from OSRM for this route.

Longest stretch: Talbutt Street — detailed segment metrics are refreshing.

Turn-by-Turn Driving Directions

Step-by-step road directions between Greenfield, MO and St. Louis, MO.

1

Start on South Allison Avenue

0.3 mi · 1 min · South Allison Avenue
2

At the end of the road, turn left onto Talbutt Street

184 ft · 10 sec · Talbutt Street
3

Turn right onto Lilly Street

0.2 mi · 50 sec · Lilly Street
4

Turn right onto N Grand Street

31 mi · 42 min · N Grand Street
5

Enter the roundabout and take exit 1 toward the route

95 ft · 3 sec · the route
6

Exit the roundabout

0.6 mi · 48 sec
7

Enter the roundabout and take exit 2 toward the route

128 ft · 4 sec · the route
8

Exit the roundabout

1.3 mi · 1 min
9

Enter the roundabout and take exit 2 toward the route

108 ft · 5 sec · the route
10

Exit the roundabout

3.6 mi · 4 min
11

Take the ramp left

0.3 mi · 40 sec
12

Merge slight left onto Payne Stewart Highway

201 mi · 3 hr 39 min · Payne Stewart Highway
13

Continue on Police Officer Ernest M. Brockman Sr. Memorial Highway

3.5 mi · 4 min · Police Officer Ernest M. Brockman Sr. Memorial Highway
14

Continue on Police Officer Robert Stanze Memorial Highway

2.7 mi · 3 min · Police Officer Robert Stanze Memorial Highway
15

Continue on Officer Michael Barwick Memorial Highway

3.5 mi · 4 min · Officer Michael Barwick Memorial Highway
16

Continue on Officer David Haynes Memorial Highway

2.3 mi · 3 min · Officer David Haynes Memorial Highway
17

Take the exit slight right toward Jefferson Avenue

0.2 mi · 22 sec · Jefferson Avenue
18

Turn left onto South Jefferson Avenue

1.3 mi · 2 min · South Jefferson Avenue
19

Turn right onto Market Street

1.0 mi · 1 min · Market Street
20

Arrive at your destination

Trip Plan

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 126.8 miles from Greenfield, MO, or about 2h 1m into the drive.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 80 miles or 1h 16m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 126.8 miles or 2h 1m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 3h 20m

Traffic, exits, and arrival timing usually matter more near St. Louis, MO than in the middle of the route.

Before You Leave

+

Open the route before leaving Greenfield, MO so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Greenfield, MO

This is one driving day of about 253.5 miles and 4h 3m.

Your first comfortable stop window is around 80 miles from Greenfield, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 126.8 mi from Greenfield, MO · 2h 1m into the drive

Downtown Cahokia, IL, IL

Mid-route town

Meal stop

Cahokia, IL

127 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Bentonville, AR

Fuel and coffee

A short stop after about 80 miles helps settle the day before fatigue starts building.

Cahokia, IL

Meal break

The midpoint is around 126.8 miles from Greenfield, MO, which is a good place for a longer meal and fuel stop.

Arriving in St. Louis, MO

The final approach into St. Louis, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around St. Louis, MO.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$38.50 one way

$77.01 round trip

$3.86/gal 25.4 MPG avg 89 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.25 $42.45 $84.89
premium $4.80 $47.86 $95.71
diesel $5.64 $56.32 $112.64

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$39

Meals

$25–$50

Total

$64–$89

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 88.7 kg one way. Prices: EIA weekly data, 2026-04-06.

Driving Electric?

About $27 in charging · 0 stops · 66% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 76.1 0 $26.62 $12.17
Efficient EV 63.4 0 $22.18 $10.14
EV Truck/SUV 101.4 1 $35.49 $16.22

Gas CO2

89 kg

EV CO2

30 kg (66% less)

Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast data refreshed 2 days ago

Origin

Greenfield, MO

Afternoon in Greenfield on Sunday

Local time

2:36 PM

CDT

Current temp

55°F

Unavailable

Live forecast

Destination

St. Louis, MO

Afternoon in St. Louis on Sunday

Local time

2:36 PM

CDT

Current temp

59°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

4 degrees warmer at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

4h 3m on the road

An early start around 7-8 AM gets you there with plenty of daylight left.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Greenfield, MO to St. Louis, MO covers 253.5 miles and takes about 4h 3m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are Talbutt Street, Lilly Street, N Grand Street. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 126.8 miles from Greenfield, MO. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $38.50 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a straightforward 4h 3m drive. You will face about 0 decision points, but nothing that requires special attention if you follow navigation.
This route does not have any notably tricky sections. Most of the drive from Greenfield, MO to St. Louis, MO is straightforward, with well-signed roads and simple exits.
The route from Greenfield, MO to St. Louis, MO does not surface many named destination signs beyond the main corridor.

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