The drive from Gulf Hills, MS to Greenville, MS covers 283.8 miles and takes about 5h 56m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on US 49, US 49W, Medgar Evers Boulevard for much of the mileage,
and the overall profile is highway-focused drive.
The longest uninterrupted segment is about 140.6 miles on US 49.
At current regular gas prices, budget about $42.86 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
141.9 miles from Gulf Hills, MS
A natural place for your longest stop of the day
, about 2h 58m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 5h 56m. Total distance: 283.8 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
5h 56m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (84%). Some complex stretches to watch for.
Drive Character
This is a 5h 56m highway drive covering 283.8 miles, with most of the trip on US 49 and US 49W. The longest continuous stretch is about 140.6 miles on US 49.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 38 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
US 49 is the longest continuous segment at about 140.6 miles.
How Hard Is This Drive?
This is a straightforward highway drive that stays mostly on US 49 and US 49W. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.2 miles in near Shore Drive.
Driving Effort10/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 26 significant decision points across 283.8 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 0.2 miles (Shore Drive): Navigation decision point; at 5.3 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 5.6 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Critical Maneuvers
5 of 26 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
5
0.2 mi into trip|~0m in|Shore Drive
Turn right onto Shore Drive
Navigation decision point
6
5.3 mi into trip|~10m in
Take the exit toward I 110, MS 15, MS 67: Biloxi, Keesler Air Force Base
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Exit 46D-B
Toward I 110, MS 15, MS 67: Biloxi, Keesler Air...
7
5.6 mi into trip|~10m in
Keep slight right at fork toward MS 15, MS 67: MS 15, MS 67
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Exit 46C
Toward MS 15, MS 67: MS 15, MS 67
6
26.4 mi into trip|~35m in
Keep slight right at fork toward US 49 North: Hattiesburg, Jackson
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward US 49 North: Hattiesburg, Jackson
6
163.5 mi into trip|~3h 25m in|I 20; US 49
Keep slight right at fork onto I 20; US 49 toward I 20 West, US 49 North: Vicksburg, Yazoo City
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward I 20 West, US 49 North: Vicksburg, Yazoo...
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Gulf Hills, MS and Greenville, MS, road signs point toward Jackson, Yazoo City and Vicksburg.
Jackson
26.4 mi in|~35m
Yazoo City
163.5 mi in|~3h 25m|via I 20; US 49
Vicksburg
211.2 mi in|~4h 23m|via US 49W
Main Roads
Road
Distance
Duration
US 49
140.6 mi
2h 53m
US 49W
46.7 mi
56m
Medgar Evers Boulevard
39.5 mi
48m
Biloxi-D'Iberville Scenic Expressway
20.4 mi
23m
US 82
15.8 mi
19m
MS 182
9.2 mi
13m
I 20
4.3 mi
5m
I 10
2.2 mi
2m
Longest stretch:
US 49
— 140.6 mi, about 2h 53m
Turn-by-Turn Driving Directions
Step-by-step road directions between Gulf Hills, MS and Greenville, MS.
1
Start on West el Bonito Drive
0.2 mi·55 sec·West el Bonito Drive
2
Turn right onto Shore Drive
0.1 mi·25 sec·Shore Drive
3
Continue on Shore Drive
192 ft·8 sec·Shore Drive
4
Continue on Ridge Road
0.2 mi·58 sec·Ridge Road
5
Turn left
288 ft·12 sec
6
Continue on Hugh Seymour Lane
0.2 mi·48 sec·Hugh Seymour Lane
7
Turn left onto MS 609
1.9 mi·3 min·Washington Avenue
8
Turn left
0.4 mi·49 sec
9
Merge onto I 10
2.2 mi·2 min·I 10
10
Take the exit
0.2 mi·20 sec
Exit 46D-BToward I 110, MS 15, MS 67: Biloxi, Keesler Air Force Base
11
Keep slight left at fork
0.2 mi·23 sec
12
Keep slight right at fork
0.4 mi·46 sec
Exit 46CToward MS 15, MS 67: MS 15, MS 67
13
Merge onto MS 15; MS 67
20 mi·23 min·Biloxi-D'Iberville Scenic Expressway
Use the straight lane.
14
Keep slight right at fork
0.4 mi·47 sec
Toward US 49 North: Hattiesburg, Jackson
15
Merge onto US 49
40 mi·46 min·US 49
Use the straight lane.
16
Continue on US 49
2.4 mi·2 min·US 49
Use the straight / slight right lanes.
17
Turn straight onto US 49
10 mi·16 min·US 49
Use the straight lane.
18
Continue on US 49; MS 42
5.4 mi·6 min·US 49; MS 42
Use the straight lane.
19
Continue on US 49
5.3 mi·6 min·US 49
Use the straight lane.
20
Continue on US 49
0.2 mi·14 sec·US 49
Use the straight lane.
21
Continue on US 49
4.2 mi·4 min·US 49
Use the straight lane.
22
Continue on US 49
66 mi·1 hr 20 min·US 49
Use the straight lane.
23
Take the exit onto US 49
0.2 mi·21 sec·US 49
24
Keep slight left at fork onto US 49
0.7 mi·1 min·US 49
Toward Jackson
25
Keep slight left at fork onto US 49
1.0 mi·1 min·US 49
26
Merge onto I 20; I 55; US 49
1.6 mi·2 min·I 20; I 55; US 49
27
Keep slight right at fork onto I 20; US 49
2.7 mi·3 min·I 20; US 49
Toward I 20 West, US 49 North: Vicksburg, Yazoo City
28
Take the exit onto US 49
5.2 mi·6 min·US 49
Toward I 220 North, I 49 North: North Jackson, Yazoo City
29
Take the exit onto US 49
0.3 mi·33 sec·US 49
Toward US 49 North: Yazoo City
30
Merge onto US 49
39 mi·48 min·Medgar Evers Boulevard
31
Take the exit onto US 49W
47 mi·56 min·US 49W
Toward US 49W North, MS 3 South: Indianola, Vicksburg
32
Turn left onto US 82
2.4 mi·3 min·US 82
33
Keep slight left at fork onto US 82
0.4 mi·29 sec·US 82
34
Keep slight left at fork onto US 82
13 mi·15 min·US 82
35
Turn right onto MS 182
9.2 mi·13 min·MS 182
36
Turn right onto South Main Street
0.9 mi·2 min·South Main Street
37
Turn right onto MS 814
10 ft·0 sec·South Broadway Street
38
Arrive at destination
MS 814
Trip Plan
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 141.9 miles from Gulf Hills, MS, or about 2h 58m into the drive.
The longest continuous stretch on this route runs about 140.6 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 62 miles or 1h 17m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 141.9 miles or 2h 58m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 50m
Traffic, exits, and arrival timing usually matter more near Greenville, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving Gulf Hills, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Gulf Hills, MS
This is one driving day of about 283.8 miles and 5h 56m.
Your first comfortable stop window is around 62 miles from Gulf Hills, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on US 49 for about 140.6 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 141.9 mi from Gulf Hills, MS
· 2h 58m into the drive
The midpoint is around 141.9 miles from Gulf Hills, MS, which is a good place for a longer meal and fuel stop.
Arriving in Greenville, MS
The final approach into Greenville, MS usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Greenville, MS.
After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
National Parks Near This Route
Worth a detour if your schedule allows.
Medgar and Myrlie Evers Home National Monument
National Monument
Medgar and Myrlie Evers were partners in the civil rights struggle. The assassination of Medgar Evers in the carport of their home on June 12, 1963, was the first murder of a nationally significant le...
4 mi from route
~10 min detour
Free
near mile 166.4
Park data from the National Park Service API. Alerts update every 2 hours.
Fuel & Cost
Regular Gas
$42.86 one way
$85.72 round trip
$3.84/gal25.4 MPG avg99 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.21
$47.05
$94.10
premium
$4.56
$50.94
$101.88
diesel
$5.61
$62.66
$125.32
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$43
Meals
$25–$50
Total
$68–$93
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 99.3 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $30 in charging
· 1 stop
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
85.1
1
$29.80
$13.62
Efficient EV
71
0
$24.83
$11.35
EV Truck/SUV
113.5
1
$39.73
$18.16
Gas CO2
99 kg
EV CO2
33 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Gulf Hills, MS
Morning
in Gulf Hills on Saturday
Local time
10:49 AM
CDT
Current temp
58°F
Unavailable
Live forecast
Destination
Greenville, MS
Morning
in Greenville on Saturday
Local time
10:49 AM
CDT
Current temp
77°F
Unavailable
Live forecast
55°F
Florence, MS
142 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
19 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
5h 56m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Gulf Hills, MS to Greenville, MS covers 283.8 miles and takes about 5h 56m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are US 49, US 49W, Medgar Evers Boulevard. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 141.9 miles from Gulf Hills, MS. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $42.86 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 26 significant decision points across 283.8 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 0.2 miles (Shore Drive): Navigation decision point; at 5.3 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 5.6 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Between Gulf Hills, MS and Greenville, MS, road signs point toward Jackson, Yazoo City and Vicksburg.
How this page is built
Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.