Gulfport, MS to Flora, MS is 180.2 miles and takes about 3h 45m via US 49, with a fuel budget near $27 and enough daylight to finish in a day. This trip takes you from the Southeast region of Mississippi all the way back into the Southeast, staying within the same state. It's a mixed drive, meaning you'll encounter a variety of road types, not just a straight shot on one highway. With a recommended one-day duration and a reasonable fuel cost, this route is a manageable journey for anyone looking to travel north within Mississippi.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
90.1 miles from Gulfport, MS
A natural place for your longest stop of the day
, about 1h 53m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 3h 45m. Total distance: 180.2 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
3h 45m drive, comfortable solo distance.
Scenic Drive
Mixed drive route profile with national parks nearby.
Drive Character
This drive offers a mixed experience, with 58% of it being highway driving. You'll spend a significant portion of your time on US 49, which includes a substantial uninterrupted stretch of 100.8 miles. As you progress, expect the road character to shift, moving from potentially more urban or suburban areas near Gulfport to more open stretches as you head north. The main roads you'll utilize include US 49, 25th Avenue, and Medgar Evers Boulevard, indicating a blend of main highways and city access roads.
Expect a mix of faster highway mileage and slower local approaches near the beginning or end.
There are about 21 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
US 49 is the longest continuous segment at about 100.8 miles.
How Hard Is This Drive?
This route mixes highway mileage with some local-road sections near the start or finish. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 153.7 miles in near US 49.
Driving Effort9/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 11 significant decision points across 180.2 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 153.7 miles (US 49): Highway fork - watch signs carefully; at 154.4 miles (US 49): Highway fork - watch signs carefully; at 157.1 miles (I 20; US 49): Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Critical Maneuvers
5 of 11 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
5
153.7 mi into trip|~3h 11m in|US 49
Keep slight left at fork onto US 49 toward Jackson
Highway fork - watch signs carefully
Toward Jackson
4
154.4 mi into trip|~3h 13m in|US 49
Keep slight left at fork onto US 49
Highway fork - watch signs carefully
6
157.1 mi into trip|~3h 16m in|I 20; US 49
Keep slight right at fork onto I 20; US 49 toward I 20 West, US 49 North: Vicksburg, Yazoo City
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward I 20 West, US 49 North: Vicksburg, Yazoo...
5
159.8 mi into trip|~3h 19m in|US 49
Take the exit onto US 49 toward I 220 North, I 49 North: North Jackson, Yazoo City
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Toward I 220 North, I 49 North: North Jackson,...
5
179.7 mi into trip|~3h 44m in|MS 22 / West Madison Street
Turn right onto MS 22 / West Madison Street
Navigation decision point
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Gulfport, MS and Flora, MS, road signs point toward Jackson and Yazoo City.
Jackson
153.7 mi in|~3h 11m|via US 49
Yazoo City
157.1 mi in|~3h 16m|via I 20; US 49
Main Roads
Road
Distance
Duration
US 49
100.8 mi
2h 6m
25th Avenue
60.1 mi
1h 14m
Medgar Evers Boulevard
14.1 mi
17m
I 20
4.3 mi
5m
West Madison Street
0.3 mi
<1m
South 4th Street
0.2 mi
<1m
East Main Street
0.2 mi
<1m
Peach Street
0.1 mi
<1m
Longest stretch:
US 49
— 100.8 mi, about 2h 6m
Turn-by-Turn Driving Directions
Step-by-step road directions between Gulfport, MS and Flora, MS.
1
Start on US 49
60 mi·1 hr 14 min·25th Avenue
Use the straight lane.
2
Continue on US 49
2.4 mi·2 min·US 49
Use the straight / slight right lanes.
3
Turn straight onto US 49
10 mi·16 min·US 49
Use the straight lane.
4
Continue on US 49; MS 42
5.4 mi·6 min·US 49; MS 42
Use the straight lane.
5
Continue on US 49
5.3 mi·6 min·US 49
Use the straight lane.
6
Continue on US 49
0.2 mi·14 sec·US 49
Use the straight lane.
7
Continue on US 49
4.2 mi·4 min·US 49
Use the straight lane.
8
Continue on US 49
66 mi·1 hr 20 min·US 49
Use the straight lane.
9
Take the exit onto US 49
0.2 mi·21 sec·US 49
10
Keep slight left at fork onto US 49
0.7 mi·1 min·US 49
Toward Jackson
11
Keep slight left at fork onto US 49
1.0 mi·1 min·US 49
12
Merge onto I 20; I 55; US 49
1.6 mi·2 min·I 20; I 55; US 49
13
Keep slight right at fork onto I 20; US 49
2.7 mi·3 min·I 20; US 49
Toward I 20 West, US 49 North: Vicksburg, Yazoo City
14
Take the exit onto US 49
5.2 mi·6 min·US 49
Toward I 220 North, I 49 North: North Jackson, Yazoo City
15
Take the exit onto US 49
0.3 mi·33 sec·US 49
Toward US 49 North: Yazoo City
16
Merge onto US 49
14 mi·17 min·Medgar Evers Boulevard
17
Turn right onto MS 22
0.1 mi·21 sec·Peach Street
18
Turn left onto MS 22
0.2 mi·26 sec·South 4th Street
19
Turn right onto MS 22
0.3 mi·29 sec·West Madison Street
20
Continue on MS 22
0.2 mi·23 sec·East Main Street
21
Arrive at destination
MS 22
Trip Plan
Consider departing in the morning to make the most of the 3-hour and 45-minute drive, allowing for flexibility if you encounter unexpected delays. With a total distance of 180.2 miles and a fuel cost estimated at $27, this trip is well-suited for a single day. You'll have one recommended stop, but with a longest stretch of over 100 miles on US 49, be sure to fuel up before leaving the more populated areas. Planning your departure around avoiding peak traffic in the initial sections near Gulfport can also enhance your journey.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 90.1 miles from Gulfport, MS, or about 1h 53m into the drive.
The longest continuous stretch on this route runs about 100.8 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 40 miles or 49m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 90.1 miles or 1h 53m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 4m
Traffic, exits, and arrival timing usually matter more near Flora, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving Gulfport, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Gulfport, MS
This is one driving day of about 180.2 miles and 3h 45m.
Your first comfortable stop window is around 40 miles from Gulfport, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on US 49 for about 100.8 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 90.1 mi from Gulfport, MS
· 1h 53m into the drive
Place data sourced from public business listings. Hours and availability may vary.
National Parks Near This Route
Worth a detour if your schedule allows.
Medgar and Myrlie Evers Home National Monument
National Monument
Medgar and Myrlie Evers were partners in the civil rights struggle. The assassination of Medgar Evers in the carport of their home on June 12, 1963, was the first murder of a nationally significant le...
3 mi from route
~7 min detour
Free
near mile 161.6
Park data from the National Park Service API. Alerts update every 2 hours.
Fuel & Cost
Regular Gas
$27.21 one way
$54.43 round trip
$3.84/gal25.4 MPG avg63 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.21
$29.87
$59.75
premium
$4.56
$32.34
$64.69
diesel
$5.61
$39.79
$79.57
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$27
Meals
$25–$50
Total
$52–$77
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 63 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $19 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
54.1
0
$18.92
$8.65
Efficient EV
45.1
0
$15.77
$7.21
EV Truck/SUV
72.1
0
$25.23
$11.53
Gas CO2
63 kg
EV CO2
21 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Gulfport, MS
Late night
in Gulfport on Saturday
Local time
4:42 AM
CDT
Current temp
60°F
Unavailable
Live forecast
Destination
Flora, MS
Late night
in Flora on Saturday
Local time
4:42 AM
CDT
Current temp
55°F
Unavailable
Live forecast
58°F
Sumrall, MS
90 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
5 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
3h 45m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Gulfport, MS to Flora, MS covers 180.2 miles and takes about 3h 45m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are US 49, 25th Avenue, Medgar Evers Boulevard. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 90.1 miles from Gulfport, MS. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $27.21 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. A short stop every 2 to 3 hours is enough for this drive.
This is a demanding drive. With 11 significant decision points across 180.2 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 153.7 miles (US 49): Highway fork - watch signs carefully; at 154.4 miles (US 49): Highway fork - watch signs carefully; at 157.1 miles (I 20; US 49): Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Between Gulfport, MS and Flora, MS, road signs point toward Jackson and Yazoo City.
Yes. Nearby national parks include Medgar and Myrlie Evers Home National Monument.
How this page is built
Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.
