The drive from Guthrie, KY to Owensboro, KY covers 93.1 miles and takes about 1h 57m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on US 431, Clarksville Road, Russellville Road for much of the mileage,
and the overall profile is highway-focused drive.
The longest uninterrupted segment is about 72.2 miles on US 431.
At current regular gas prices, budget about $14.56 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Midpoint
46.6 miles from Guthrie, KY
A natural place for your longest stop of the day
, about 1h into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 1h 57m. Total distance: 93.1 miles.
Family Friendly
Moderate complexity with 0 natural rest stops along the way.
This is a 1h 57m highway drive covering 93.1 miles, with most of the trip on US 431 and Clarksville Road. The longest continuous stretch is about 72.2 miles on US 431.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 9 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
US 431 is the longest continuous segment at about 72.2 miles.
How Hard Is This Drive?
This is a straightforward highway drive that stays mostly on US 431 and Clarksville Road. Navigation is very simple - set it and forget it for most of the drive. The trickiest moment comes around 0.9 miles in near US 79 / Russellville Road.
Driving Effort1/10
Very easy - short and simple to drive
Balances navigation complexity with total wheel time.
The drive from Guthrie, KY to Owensboro, KY is easy. At 1h 57m with 78% highway, most drivers will find it relaxed and low-stress.
Where does it get tricky?
The main spots that need attention: at 0.9 miles (US 79 / Russellville Road): Navigation decision point; at 23.1 miles (US 431): Lane positioning matters here; at 60.7 miles (US 431): Lane positioning matters here.
Critical Maneuvers
3 of 3 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
5
0.9 mi into trip|~1m in|US 79 / Russellville Road
At end of road, turn right onto US 79 / Russellville Road
Navigation decision point
5
23.1 mi into trip|~33m in|US 431
Turn left onto US 431
Lane positioning matters here
Use the straight lane.
5
60.7 mi into trip|~1h 16m in|US 431
Turn right onto US 431
Lane positioning matters here
Use the right lane.
Main Roads
Road
Distance
Duration
US 431
72.2 mi
1h 26m
Clarksville Road
10.6 mi
15m
Russellville Road
8.9 mi
13m
Ewing Street
0.9 mi
1m
KY 1031
0.5 mi
<1m
West 9th Street
0.1 mi
<1m
Frederica Street
—
—
Some road-level metrics are being recalculated.
Longest stretch:
US 431
— 72.2 mi, about 1h 26m
Turn-by-Turn Driving Directions
Step-by-step road directions between Guthrie, KY and Owensboro, KY.
1
Start on US 41
0.9 mi·1 min·Ewing Street
2
At end of road, turn right onto US 79
8.9 mi·13 min·Russellville Road
3
Continue on US 79
11 mi·15 min·Clarksville Road
4
Continue on US 79
0.1 mi·13 sec·West 9th Street
5
Turn left onto US 431
2.6 mi·3 min·US 431
6
Turn left onto US 431
37 mi·42 min·US 431
Use the straight lane.
7
Continue on KY 1031
0.5 mi·35 sec·KY 1031
8
Turn right onto US 431
32 mi·40 min·US 431
Use the right lane.
9
Arrive at destination
Frederica Street
Trip Plan
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 46.6 miles from Guthrie, KY, or about 1h into the drive.
The longest continuous stretch on this route runs about 72.2 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 20 miles or 29m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 46.6 miles or 1h in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 1h 36m
Traffic, exits, and arrival timing usually matter more near Owensboro, KY than in the middle of the route.
Before You Leave
+
Open the route before leaving Guthrie, KY so your first major turns are already loaded.
Day 1
Settle into the route from Guthrie, KY
This is one driving day of about 93.1 miles and 1h 57m.
Your first comfortable stop window is around 20 miles from Guthrie, KY.
This route can stay practical as a one-day drive if traffic stays reasonable.
The longest stretch is on US 431 for about 72.2 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 46.6 mi from Guthrie, KY
· 1h into the drive
Place data sourced from public business listings. Hours and availability may vary.
Fuel & Cost
Regular Gas
$14.56 one way
$29.11 round trip
$3.97/gal25.4 MPG avg33 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.36
$15.98
$31.96
premium
$4.89
$17.92
$35.83
diesel
$5.61
$20.56
$41.11
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$15
Meals
$25–$50
Total
$40–$65
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 32.6 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $10 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
27.9
0
$9.78
$4.47
Efficient EV
23.3
0
$8.15
$3.72
EV Truck/SUV
37.2
0
$13.03
$5.96
Gas CO2
33 kg
EV CO2
11 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 18, 2026
Origin
Guthrie, KY
Late night
in Guthrie on Saturday
Local time
3:41 AM
CDT
Current temp
67°F
Mostly Cloudy
S 6 to 9 mph10% chanceLive forecast
Destination
Owensboro, KY
Late night
in Owensboro on Saturday
Local time
3:41 AM
CDT
Current temp
76°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
9 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
1h 57m on the road
The weather snapshot is not static. If you are leaving later, give both cities one more quick forecast check before departure.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Guthrie, KY to Owensboro, KY covers 93.1 miles and takes about 1h 57m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are US 431, Clarksville Road, Russellville Road. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 46.6 miles from Guthrie, KY. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $14.56 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Leave by 9 AM and you'll arrive before lunch. Even a 4 PM departure gets you there before dark in summer.
The drive from Guthrie, KY to Owensboro, KY is easy. At 1h 57m with 78% highway, most drivers will find it relaxed and low-stress.
The main spots that need attention: at 0.9 miles (US 79 / Russellville Road): Navigation decision point; at 23.1 miles (US 431): Lane positioning matters here; at 60.7 miles (US 431): Lane positioning matters here.
The route from Guthrie, KY to Owensboro, KY does not surface many named destination signs beyond the main corridor.
