Origin
Hendry County, FL
Night in Hendry County on Thursday
Local time
10:31 PM
EDT
Current temp
80°F
Unavailable
Live forecast
Trip from Hendry County, FL to Gainesville, FL
Last recalculated Apr 17, 2026
Drive Time
5h 23m
Distance
250.3 mi
403 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$40
one way
EV Charging
Unknown
Best Time to Leave
4 AM
5h 10m
★
6 AM
5h 24m
8 AM
5h 50m
10 AM
5h 33m
12 PM
5h 30m
3 PM
5h 34m
5 PM
5h 49m
8 PM
5h 16m
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Hendry County, FL
Wikimedia Commons
Trip Overview
The drive from Hendry County, FL to Gainesville, FL covers 250.3 miles and takes about 5h 23m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on US 27, I 75, Florida's Turnpike for much of the mileage, and the overall profile is highway-focused drive. The longest uninterrupted segment is about 154.6 miles on US 27. At current regular gas prices, budget about $39.84 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
125.2 miles from Hendry County, FL
A natural place for your longest stop of the day , about 2h 47m into the drive .
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 5h 23m. Total distance: 250.3 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
5h 23m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (92%). Some complex stretches to watch for.
Drive Character
This is a 5h 23m highway drive covering 250.3 miles, with most of the trip on US 27 and I 75. The longest continuous stretch is about 154.6 miles on US 27.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 31 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
US 27 is the longest continuous segment at about 154.6 miles.
How Hard Is This Drive?
This is a straightforward highway drive that stays mostly on US 27 and I 75. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 16.4 miles in.
Driving Effort
8/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 18 significant decision points across 250.3 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 16.4 miles: Highway fork - watch signs carefully; at 16.7 miles (FL 80): Multiple destination signs - pick the right one; at 172.5 miles (Florida's Turnpike): Merge point - match speed before joining. Lane positioning matters here.
Critical Maneuvers
5 of 18 key pointsThese are the spots where you need to pay the most attention. Preview them before you drive.
5
16.4 mi into trip
|
~27m in
Keep slight left at fork toward US 27 North: Sebring
Highway fork - watch signs carefully
Toward US 27 North: Sebring
6
16.7 mi into trip
|
~27m in
|
FL 80
Turn left onto FL 80 toward FL 80 West: La Belle, Fort Myers
Multiple destination signs - pick the right one
Toward FL 80 West: La Belle, Fort Myers
5
172.5 mi into trip
|
~3h 55m in
|
Florida's Turnpike
Merge onto Florida's Turnpike
Merge point - match speed before joining. Lane positioning matters here
Use the straight / slight right lanes.
7
191.4 mi into trip
|
~4h 15m in
|
Florida's Turnpike
Keep slight left at fork onto Florida's Turnpike toward I 75 North: Ocala
Highway fork - watch signs carefully. Lane positioning matters here
Use the straight lane.
Toward I 75 North: Ocala
7
237.8 mi into trip
|
~5h 4m in
Take the exit toward CR 234: Micanopy
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the straight / slight right lanes.
Exit 374
Toward CR 234: Micanopy
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Hendry County, FL and Gainesville, FL, road signs point toward Fort Myers, Florida's Turnpike North: Ocala and Cr 234: Micanopy.
Fort Myers
16.7 mi in
|
~27m
|
via FL 80
Florida's Turnpike North: Ocala
172 mi in
|
~3h 53m
Cr 234: Micanopy
237.8 mi in
|
~5h 4m
Main Roads
| Road | Distance | Duration |
|---|---|---|
| US 27 | 154.6 mi | 3h 24m |
| I 75 | 46.1 mi | 49m |
| Florida's Turnpike | 19.1 mi | 20m |
| Sam Jones Trail | 9.8 mi | 16m |
| US 441 | 8 mi | 9m |
| South Devil's Garden Road | 3.9 mi | 6m |
| FL 80 | 3.3 mi | 4m |
| South Main Street | 2.4 mi | 4m |
Longest stretch:
US 27
— 154.6 mi, about 3h 24m
Turn-by-Turn Driving Directions
Step-by-step road directions between Hendry County, FL and Gainesville, FL.
1
Start on CR 833
3.7 mi
·
6 min
·
Sam Jones Trail
2
Continue on CR 833
3.9 mi
·
6 min
·
South Devil's Garden Road
3
Continue on CR 833
6.1 mi
·
10 min
·
Sam Jones Trail
4
Turn right onto FL 80
2.7 mi
·
3 min
·
FL 80
5
Keep slight left at fork
0.3 mi
·
39 sec
Toward US 27 North: Sebring
6
Turn left onto FL 80
0.6 mi
·
1 min
·
FL 80
Toward FL 80 West: La Belle, Fort Myers
7
Merge onto US 27
48 mi
·
58 min
·
US 27
8
Continue on US 27
0.2 mi
·
19 sec
·
US 27
Use the left lane.
9
Continue on US 27
10 mi
·
12 min
·
US 27
Use the left lane.
10
Continue on US 27
42 mi
·
55 min
·
US 27
Use the left / straight lanes.
11
Continue on US 27
28 mi
·
39 min
·
US 27
Use the left lane.
12
Continue on US 27
14 mi
·
19 min
·
US 27
Use the left lane.
13
Continue on US 27
10 mi
·
14 min
·
US 27
14
Continue on US 27
0.3 mi
·
23 sec
·
US 27
15
Keep slight right at fork onto US 27
3.0 mi
·
4 min
·
US 27
16
Take the exit
0.2 mi
·
22 sec
Toward Florida's Turnpike North: Ocala
17
Continue on this road
0.4 mi
·
48 sec
·
this road
Toward Florida's Turnpike North: Ocala
18
Merge onto Florida's Turnpike
19 mi
·
20 min
·
Florida's Turnpike
Use the straight / slight right lanes.
19
Keep slight left at fork onto Florida's Turnpike
0.2 mi
·
15 sec
·
Florida's Turnpike
Toward I 75 North: Ocala
Use the straight lane.
20
Merge onto I 75
46 mi
·
49 min
·
I 75
Use the straight / slight right lanes.
21
Take the exit
0.2 mi
·
31 sec
Exit 374
Toward CR 234: Micanopy
Use the straight / slight right lanes.
22
Turn right onto CR 234
1.3 mi
·
2 min
·
Southeast County Road 234
23
Turn left
421 ft
·
15 sec
Use the left lane.
24
Turn straight onto US 441
8.0 mi
·
9 min
·
US 441
Use the straight lane.
25
Turn right onto FL 331
0.5 mi
·
1 min
·
Southwest Williston Road
Use the right lane.
26
Turn left onto CR 329
1.6 mi
·
2 min
·
South Main Street
27
Enter roundabout onto CR 329
92 ft
·
1 sec
·
South Main Street
28
Continue on CR 329
0.2 mi
·
32 sec
·
South Main Street
29
Enter roundabout onto CR 329
177 ft
·
3 sec
·
South Main Street
30
Continue on CR 329
0.5 mi
·
1 min
·
South Main Street
Use the straight / right lanes.
31
Arrive at destination
CR 329
Trip Plan
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 125.2 miles from Hendry County, FL, or about 2h 47m into the drive.
The longest continuous stretch on this route runs about 154.6 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 55 miles or 1h 15m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 125.2 miles or 2h 47m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 30m
Traffic, exits, and arrival timing usually matter more near Gainesville, FL than in the middle of the route.
Before You Leave
+
Open the route before leaving Hendry County, FL so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Hendry County, FL
This is one driving day of about 250.3 miles and 5h 23m.
Your first comfortable stop window is around 55 miles from Hendry County, FL.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on US 27 for about 154.6 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 125.2 mi from Hendry County, FL · 2h 47m into the drive
Mid-route town
Meal stop
125 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
Pacing Suggestions
Fuel and coffee
A short stop after about 55 miles helps settle the day before fatigue starts building.
Meal break
The midpoint is around 125.2 miles from Hendry County, FL, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before US 27 if your tank is already low. That segment runs about 154.6 miles.
Arriving in Gainesville, FL
The final approach into Gainesville, FL usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Gainesville, FL.
After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Fuel & Cost
Regular Gas
$39.84 one way
$79.68 round trip
$4.04/gal
25.4 MPG avg
88 kg CO2
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.40 | $43.34 | $86.68 |
| premium | $4.72 | $46.54 | $93.08 |
| diesel | $5.61 | $55.26 | $110.53 |
Estimated Tolls: $1.32
Florida's Turnpike
(18.9 mi)
$1.32
Toll estimates based on average 2024-2025 rates. EZ-Pass/SunPass discounts may lower the actual cost.
Estimated Trip Cost (one way, 1 person)
Fuel
$40
Tolls
$1
Meals
$25–$50
Total
$66–$91
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 87.6 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $26 in charging · 0 stops · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 75.1 | 0 | $26.28 | $12.01 |
| Efficient EV | 62.6 | 0 | $21.90 | $10.01 |
| EV Truck/SUV | 100.1 | 1 | $35.04 | $16.02 |
Gas CO2
88 kg
EV CO2
29 kg (67% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Destination
Gainesville, FL
Night in Gainesville on Thursday
Local time
10:31 PM
EDT
Current temp
81°F
Unavailable
Live forecast
62°F
Eagle Lake, FL
125 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
1 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
5h 23m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Hendry County, FL to Gainesville, FL covers 250.3 miles and takes about 5h 23m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are US 27, I 75, Florida's Turnpike. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 125.2 miles from Hendry County, FL. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $39.84 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 18 significant decision points across 250.3 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 16.4 miles: Highway fork - watch signs carefully; at 16.7 miles (FL 80): Multiple destination signs - pick the right one; at 172.5 miles (Florida's Turnpike): Merge point - match speed before joining. Lane positioning matters here.
Between Hendry County, FL and Gainesville, FL, road signs point toward Fort Myers, Florida's Turnpike North: Ocala and Cr 234: Micanopy.
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