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Trip from Hillsborough Park, CA to South San Francisco, CA

Last recalculated Apr 16, 2026

Drive Time

16m

Distance

10.8 mi

17 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$2

one way

Best Time to Leave

4 AM
0h 15m ★
6 AM
0h 16m
8 AM
0h 19m
10 AM
0h 17m
12 PM
0h 17m
3 PM
0h 17m
5 PM
0h 19m
8 PM
0h 15m ★

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

city in San Mateo County, California, United States

South San Francisco, CA

Wikimedia Commons

Trip Overview

The drive from Hillsborough Park, CA to South San Francisco, CA covers 10.8 miles and takes about 16m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on Junipero Serra Freeway, Quentin L. Kopp Freeway, Hayne Road for much of the mileage, and the overall profile is highway-focused drive. The longest uninterrupted segment is about 6.1 miles on Junipero Serra Freeway. At current regular gas prices, budget about $2.48 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is realistic if you keep stops short.

Break Rhythm

0 planned breaks

This drive is short enough that no stops are needed.

Midpoint

5.4 miles from Hillsborough Park, CA

A natural place for your longest stop of the day , about 8m into the drive .

Drive Character

This is a 16m highway drive covering 10.8 miles, with most of the trip on Junipero Serra Freeway and Quentin L. Kopp Freeway. The longest continuous stretch is about 6.1 miles on Junipero Serra Freeway.

Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 17 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Junipero Serra Freeway is the longest continuous segment at about 6.1 miles.

How Hard Is This Drive?

This is a straightforward highway drive that stays mostly on Junipero Serra Freeway and Quentin L. Kopp Freeway. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.9 miles in near Hayne Road.

Route Complexity 8/10

Focused - busy navigation packed into a short drive

This is a short but busy drive. With 11 decision points packed into just 10.8 miles, you will need to pay attention to lane changes and exits — but the whole thing is over in 16m.

Where does it get tricky?

The main spots that need attention: at 0.9 miles (Hayne Road): Roundabout - know your exit number before entering; at 1 miles: Lane positioning matters here; at 1.4 miles (I 280; CA 35 / Junipero Serra Freeway): Merge point - match speed before joining. Lane positioning matters here.

Critical Maneuvers

5 of 11 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

5
0.9 mi into trip | ~2m in | Hayne Road

Enter roundabout onto Hayne Road

Roundabout - know your exit number before entering

6
1 mi into trip | ~2m in

Take the ramp toward I 280 North: San Francisco

Lane positioning matters here

Use the straight / right lanes. Toward I 280 North: San Francisco
5
1.4 mi into trip | ~3m in | I 280; CA 35 / Junipero Serra Freeway

Merge onto I 280; CA 35 / Junipero Serra Freeway

Merge point - match speed before joining. Lane positioning matters here

Use the straight / slight right lanes.
7
7.5 mi into trip | ~10m in

Take the exit toward I 380 East: San Francisco International Airport

Exit ramp - move to the correct lane early. Lane positioning matters here

Use the straight / slight right lanes. Exit 43B Toward I 380 East: San Francisco International...
8
9.9 mi into trip | ~14m in

Take the exit toward South Airport Boulevard

Exit ramp - move to the correct lane early. Lane positioning matters here

Use the straight / slight right lanes. Exit 424 Toward South Airport Boulevard

Main Roads

Road Distance Duration
Junipero Serra Freeway 6.1 mi 6m
Quentin L. Kopp Freeway 1.1 mi 1m
Hayne Road 0.7 mi 1m
South Airport Boulevard 0.4 mi <1m
Airport Boulevard 0.4 mi <1m
Sandra Road 0.2 mi <1m
San Raymundo Road 0.1 mi <1m
Bayshore Freeway <0.1 mi <1m
Longest stretch: Junipero Serra Freeway — 6.1 mi, about 6m

Turn-by-Turn Driving Directions

Step-by-step road directions between Hillsborough Park, CA and South San Francisco, CA.

1

Start on San Raymundo Road

0.1 mi · 24 sec · San Raymundo Road
2

Continue on Sandra Road

0.2 mi · 39 sec · Sandra Road
3

Turn right onto Hayne Road

0.6 mi · 1 min · Hayne Road
4

Enter roundabout onto Hayne Road

161 ft · 6 sec · Hayne Road
5

Continue on Hayne Road

287 ft · 9 sec · Hayne Road
6

Continue on Golf Course Drive

377 ft · 8 sec · Golf Course Drive
7

Take the ramp

0.4 mi · 50 sec
Toward I 280 North: San Francisco Use the straight / right lanes.
8

Merge onto I 280; CA 35

6.1 mi · 6 min · Junipero Serra Freeway
Use the straight / slight right lanes.
9

Take the exit

0.4 mi · 25 sec
Exit 43B Toward I 380 East: San Francisco International Airport Use the straight / slight right lanes.
10

Continue on I 380

1.1 mi · 1 min · Quentin L. Kopp Freeway
Use the straight / slight right lanes.
11

Take the exit

0.8 mi · 1 min
Exit 6B Toward US 101 North: San Francisco
12

Merge onto US 101

527 ft · 6 sec · Bayshore Freeway
13

Take the exit

0.2 mi · 31 sec
Exit 424 Toward South Airport Boulevard Use the straight / slight right lanes.
14

Turn left onto South Airport Boulevard

0.2 mi · 27 sec · South Airport Boulevard
Use the left / straight lanes.
15

Turn left onto South Airport Boulevard

0.2 mi · 23 sec · South Airport Boulevard
Use the left lane.
16

Continue on Airport Boulevard

0.4 mi · 43 sec · Airport Boulevard
17

Arrive at destination

Airport Boulevard

Trip Plan

Morning Departure

Leave by 9 AM and you'll arrive before lunch.

Evening Departure

Even a 4 PM departure gets you there before dark in summer.

You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 5.4 miles from Hillsborough Park, CA, or about 8m into the drive.
The longest continuous stretch on this route runs about 6.1 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 10.8 miles or 16m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 5.4 miles or 8m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 12m

Traffic, exits, and arrival timing usually matter more near South San Francisco, CA than in the middle of the route.

Before You Leave

+

Have your navigation ready before leaving Hillsborough Park, CA.

Day 1

Settle into the route from Hillsborough Park, CA

This is one driving day of about 10.8 miles and 16m.

At 10.8 miles this is a quick drive — no planned stops needed.
The longest stretch is on Junipero Serra Freeway for about 6.1 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 5.4 mi from Hillsborough Park, CA · 8m into the drive

Pacing Suggestions

San Bruno, CA

Fuel and coffee

A short stop after about 10.8 miles helps settle the day before fatigue starts building.

San Bruno, CA

Meal break

The midpoint is around 5.4 miles from Hillsborough Park, CA, which is a good place for a longer meal and fuel stop.

Arriving in South San Francisco, CA

Allow a few extra minutes for the final approach into South San Francisco, CA if you are unfamiliar with the area.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$2.48 one way

$4.96 round trip

$5.84/gal 25.4 MPG avg 4 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $6.02 $2.56 $5.12
premium $6.18 $2.63 $5.25
diesel $5.61 $2.38 $4.77

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$2

Meals

$25–$50

Total

$27–$52

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 3.8 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $1 in charging · 0 stops · 75% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 3.2 0 $1.13 $0.52
Efficient EV 2.7 0 $0.95 $0.43
EV Truck/SUV 4.3 0 $1.51 $0.69

Gas CO2

4 kg

EV CO2

1 kg (75% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 15, 2026

Origin

Hillsborough Park, CA

Night in Hillsborough Park on Wednesday

Local time

10:21 PM

PDT

Current temp

--

Unavailable

Destination

South San Francisco, CA

Night in South San Francisco on Wednesday

Local time

10:21 PM

PDT

Current temp

66°F

Unavailable

Live forecast

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Road read

16m on the road

Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Hillsborough Park, CA to South San Francisco, CA covers 10.8 miles and takes about 16m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are Junipero Serra Freeway, Quentin L. Kopp Freeway, Hayne Road. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 5.4 miles from Hillsborough Park, CA. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $2.48 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Leave by 9 AM and you'll arrive before lunch. Even a 4 PM departure gets you there before dark in summer.
This is a short but busy drive. With 11 decision points packed into just 10.8 miles, you will need to pay attention to lane changes and exits — but the whole thing is over in 16m.
The main spots that need attention: at 0.9 miles (Hayne Road): Roundabout - know your exit number before entering; at 1 miles: Lane positioning matters here; at 1.4 miles (I 280; CA 35 / Junipero Serra Freeway): Merge point - match speed before joining. Lane positioning matters here.
The route from Hillsborough Park, CA to South San Francisco, CA does not surface many named destination signs beyond the main corridor.

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