The Exchange Coffee, Mercantile & Eatery
Near the start, short detour
De Pere, Wisconsin
Hours: 7 am–2 pm
Visit websiteCompiled and reviewed by the Trip.ovh planning team at COD Solutions Oy · Last reviewed Apr 17, 2026 · Editorial standards
Drive Time
4h 45m
Distance
217.4 mi
350 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$34
one way
EV Charging
Unknown
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Humboldt, WI
Mustafa Gökhan Ertin
La Crosse, WI
Wikimedia Commons
Humboldt to La Crosse is 217.4 miles and takes about 4 hours 45 minutes via I 90, I 41, and State Highway 82, with a fuel budget near $34 and enough daylight to finish in a day. This Midwest journey stays within Wisconsin, offering a straightforward drive for a single day. You'll primarily be on major highways, making it a practical option for getting from point A to point B efficiently. Consider this route if you're looking for a reliable and predictable drive with minimal fuss.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
108.7 miles from Humboldt, WI
A natural place for your longest stop of the day , about 2h 25m into the drive .
Weekend Trip
Doable as a same-day drive at 4h 45m. Total distance: 217.4 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
4h 45m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (90%). Some complex stretches to watch for.
This route is predominantly a highway-focused drive, with 90% of the journey utilizing major interstates like I 90 and I 41. Expect long stretches of consistent speed, including a longest uninterrupted segment of 62.7 miles on I 90. While the majority is highway, you'll transition to State Highway 82, which might offer a slight change in scenery and driving pace as you approach your destination. Overall, it's a drive built for covering distance with ease.
This is a straightforward highway drive that stays mostly on I 90 and I 41. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 8.8 miles in.
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 20 significant decision points across 217.4 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 8.8 miles: Exit ramp - move to the correct lane early; at 16.2 miles (I 41; US 41): Merge point - match speed before joining. Lane positioning matters here; at 65.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
These are the spots where you need to pay the most attention. Preview them before you drive.
Take the exit toward WI 172 West: Austin Straubel Airport
Exit ramp - move to the correct lane early
Merge onto I 41; US 41
Merge point - match speed before joining. Lane positioning matters here
Take the exit toward WI 44, WI 91
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Keep slight left at fork onto I 90 toward I 90 West: Tomah, La Crosse
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Take the exit toward WI 16: La Crosse, Onalaska
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
| Road | Distance | Duration |
|---|---|---|
| I 90 | 62.7 mi | 1h 7m |
| I 41 | 49.1 mi | 53m |
| State Highway 82 | 28.1 mi | 41m |
| State Highway 23 | 25.2 mi | 36m |
| State Highway 44 | 14.8 mi | 21m |
| Finger Road | 5.9 mi | 10m |
| WI 172 | 5.4 mi | 6m |
| WI 16 | 4.9 mi | 8m |
Step-by-step road directions between Humboldt, WI and La Crosse, WI.
Start on CTH T
Turn right onto CTH V
Turn left
Merge onto I 43
Take the exit
Continue on WI 172
Take the exit
Merge onto I 41; US 41
Take the exit
Keep slight right at fork
Turn right onto WI 44; WI 91
Continue on WI 44
Continue on East Oshkosh Street
Turn right onto WI 23; WI 49
Continue on WI 23; WI 49
Turn straight onto WI 23; CTH A
Continue on WI 23; WI 73
Turn left onto WI 23; WI 73; CTH D; CTH J
Turn left
Continue on WI 23
Continue on State Highway 23
Continue on WI 23; CTH C
Continue on WI 23; CTH C
Turn slight right onto WI 23; CTH C
Continue on WI 23
Continue on WI 82
Continue on WI 82
Continue on WI 82
Keep slight right at fork
Take the ramp
Merge onto I 90; I 94
Keep slight left at fork onto I 90
Take the exit
At end of road, turn left onto WI 16
Continue on Losey Boulevard North
Turn right onto CTH F
Turn left onto 16th Street South
Turn right onto Johnson Street
At end of road, turn right onto WI 35
Arrive at destination
Given the 4 hour 45 minute duration, this trip is perfectly suited for a single-day adventure. You could aim for an early morning departure to maximize your time at your destination or simply leave mid-morning and still arrive with plenty of daylight. With only one recommended stop, plan your fuel and rest breaks strategically, perhaps around the halfway point. Keep an eye on your fuel gauge, especially before embarking on the longest stretch of 62.7 miles on I 90, to ensure a smooth journey without unnecessary detours for gas.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 48 miles or 1h in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 108.7 miles or 2h 25m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 55m
Traffic, exits, and arrival timing usually matter more near La Crosse, WI than in the middle of the route.
Open the route before leaving Humboldt, WI so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Humboldt, WI
This is one driving day of about 217.4 miles and 4h 45m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 108.7 mi from Humboldt, WI · 2h 25m into the drive
Mid-route town
Meal stop
109 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 48 miles helps settle the day before fatigue starts building.
The midpoint is around 108.7 miles from Humboldt, WI, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before I 90 if your tank is already low. That segment runs about 62.7 miles.
The final approach into La Crosse, WI usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around La Crosse, WI.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Restaurants, cafes, gas stations and more along your route.
Top Restaurant
De Pere, Wisconsin
Near the start, short detour
Hours: 7 am–2 pm
Top Coffee Stop
Green Bay, Wisconsin
Near the start, short detour
Hours: 6 am–4 pm
+19205932300
Luna Coffee Roasters
De Pere, Wisconsin
Coffee Wizardz
Allouez, Wisconsin
Near the start, short detour
De Pere, Wisconsin
Hours: 7 am–2 pm
Visit websiteNear the start, ~9 min detour
Green Bay, Wisconsin
Hours: 7 am–3 pm
+19204303200
Visit websiteNear the start, ~9 min detour
Green Bay, Wisconsin
Hours: 7 am–2 pm
+19204484303
Visit websiteNear the start, short detour
Green Bay, Wisconsin
Hours: 6 am–4 pm
+19205932300
Visit websiteNear the start, short detour
De Pere, Wisconsin
Hours: 6:30 am–2 pm
Visit websiteNear the start, short detour
Allouez, Wisconsin
Hours: 7 am–2 pm
Visit websiteEarly in the drive, ~11 min detour
Appleton, Wisconsin
Hours: 7 am–3 pm
+19209392153
Visit websiteNear the start, ~10 min detour
Green Bay, Wisconsin
Hours: 7 am–2 pm
+19202722222
Visit websiteNear the start, ~12 min detour
Green Bay, Wisconsin
Hours: 7 am–3 pm
+19206007626
Visit websiteEarly in the drive, ~10 min detour
Appleton, Wisconsin
Hours: 4–9 pm
+19202053780
Visit websitePlace data sourced from public business listings. Hours and availability may vary.
Worth a detour if your schedule allows.
National Scenic Trail
The Ice Age National Scenic Trail spans 1,200 miles, traverses some of Wisconsin's finest geologic and glacial features, and passes through the ancestral lands of 15 Tribes. The Trail is built, manage...
Park data from the National Park Service API. Alerts update every 2 hours.
Regular Gas
$33.99 one way
$67.98 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.36 | $37.32 | $74.63 |
| premium | $4.89 | $41.84 | $83.67 |
| diesel | $5.61 | $48.00 | $96.00 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$34
Meals
$25–$50
Total
$59–$84
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 76.1 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $23 in charging · 0 stops · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 65.2 | 0 | $22.83 | $10.44 |
| Efficient EV | 54.4 | 0 | $19.02 | $8.70 |
| EV Truck/SUV | 87 | 1 | $30.44 | $13.91 |
Gas CO2
76 kg
EV CO2
25 kg (67% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Morning in Humboldt on Friday
Local time
8:12 AM
CDT
Current temp
58°F
Unavailable
Destination
Morning in La Crosse on Friday
Local time
8:12 AM
CDT
Current temp
56°F
Mostly Clear
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Compiled and maintained by the Trip.ovh planning team at COD Solutions Oy (Helsinki). Each route is built from authoritative open government and mapping datasets rather than crowdsourced reviews. Distances and geometry come from OSRM over OpenStreetMap. Fuel cost uses EIA weekly regional averages. National park proximity is from the NPS API. Pages are published only after passing our data-quality checks; our methodology page documents refresh cadence, editorial standards, and known limitations.
Was this helpful?
Thanks for your feedback!
Your tip has been submitted. Thanks!
/500
Recent Tips
·
Explore more options from Humboldt, WI or browse trips ending in La Crosse, WI.
Looking for more statewide routes? Browse WI road trips.