Origin
Isle of Palms, SC
Afternoon in Isle of Palms on Sunday
Local time
3:08 PM
EDT
Current temp
64°F
Unavailable
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Create accountDrive Time
4h 45m
Distance
240.1 mi
386 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$38
one way
Isle of Palms, SC
Junior Bastos
Anderson County Airport, SC
Jaxon Matthew Willis
The drive from Isle of Palms, SC to Anderson County Airport, SC covers 240.1 miles and takes about 4h 45m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on I 26, I 385, Mark Clark Expressway for much of the mileage, and the overall profile is highway-focused drive. The longest uninterrupted segment is about 158.7 miles on I 26. At current regular gas prices, budget about $38.43 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
120 miles from Isle of Palms, SC
A natural place for your longest stop of the day , about 2h 18m into the drive .
This is a 4h 45m highway drive covering 240.1 miles, with most of the trip on I 26 and I 385. The longest continuous stretch is about 158.7 miles on I 26.
This is a straightforward highway drive that stays mostly on I 26 and I 385. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 4 miles in near Hungry Neck Boulevard.
Demanding - plan breaks and stay ahead of the key maneuvers
This is a demanding drive. With 21 significant decision points across 240.1 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 4 miles (Hungry Neck Boulevard): Lane positioning matters here; at 6.2 miles (I 526 / Mark Clark Expressway): Merge point - match speed before joining. Lane positioning matters here; at 17.1 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
These are the spots where you need to pay the most attention. Preview them before you drive.
Turn left onto Hungry Neck Boulevard
Lane positioning matters here
Merge onto I 526 / Mark Clark Expressway
Merge point - match speed before joining. Lane positioning matters here
Take the exit toward US 52 West, US 78 West: Rivers Avenue
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Merge onto I 26
Merge point - match speed before joining. Lane positioning matters here
Keep slight left at fork onto I 385 toward I 385 North: Laurens, Greenville
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Between Isle of Palms, SC and Anderson County Airport, SC, road signs point toward Greenville and Pelzer.
Greenville
Pelzer
| Road | Distance | Duration |
|---|---|---|
| I 26 | 158.7 mi | 2h 53m |
| I 385 | 22.9 mi | 24m |
| Mark Clark Expressway | 11 mi | 13m |
| Highway 418 | 9.9 mi | 14m |
| Cooley Bridge Road | 5.6 mi | 8m |
| Belton Highway | 4.7 mi | 6m |
| Isle of Palms Connector | 3.6 mi | 6m |
| Highway 247 | 3.6 mi | 4m |
Step-by-step road directions between Isle of Palms, SC and Anderson County Airport, SC.
Start on SC 703
Turn left onto Isle of Palms Connector
Turn left onto Hungry Neck Boulevard
Keep slight left at fork
Merge onto I 526
Take the exit
Turn slight right onto US 52; US 78
Turn straight
Take the ramp
Merge onto I 26
Keep slight left at fork onto I 385
Take the exit
Turn left onto SC 418
Continue on SC 418
Continue on SC 418
Turn left onto US 25
Turn right onto SC 247
Continue on SC 247
Continue on SC 247
Turn left onto SC 20
Turn right onto US 76; US 178; SC 20
Continue on US 76; US 178
Continue on US 76; US 178
Turn left onto US 29
At end of road, turn left onto US 29
Turn right onto SC 28
Continue on SC 28
Turn left onto SC 24
Continue on SC 24
Turn left onto Airport Road
Continue on South Warner Road
Turn sharp left onto Airport Road
Turn right
Arrive at destination
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 34m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 120 miles or 2h 18m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 41m
Traffic, exits, and arrival timing usually matter more near Anderson County Airport, SC than in the middle of the route.
Open the route before leaving Isle of Palms, SC so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Isle of Palms, SC
This is one driving day of about 240.1 miles and 4h 45m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 120 mi from Isle of Palms, SC · 2h 18m into the drive
Mid-route town
Meal stop
120 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 80 miles helps settle the day before fatigue starts building.
The midpoint is around 120 miles from Isle of Palms, SC, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before I 26 if your tank is already low. That segment runs about 158.7 miles.
The final approach into Anderson County Airport, SC usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Anderson County Airport, SC.
After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$38.43 one way
$76.85 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.43 | $41.87 | $83.73 |
| premium | $4.78 | $45.17 | $90.33 |
| diesel | $5.64 | $53.34 | $106.68 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$38
Meals
$25–$50
Total
$63–$88
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 84 kg one way. Prices: EIA weekly data, 2026-04-06.
Driving Electric?
About $25 in charging · 0 stops · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 72 | 0 | $25.21 | $11.52 |
| Efficient EV | 60 | 0 | $21.01 | $9.60 |
| EV Truck/SUV | 96 | 1 | $33.61 | $15.37 |
Gas CO2
84 kg
EV CO2
28 kg (67% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Afternoon in Isle of Palms on Sunday
Local time
3:08 PM
EDT
Current temp
64°F
Unavailable
Destination
Afternoon in Anderson County Airport on Sunday
Local time
3:08 PM
EDT
Current temp
63°F
Unavailable
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
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Return Trip
Anderson County Airport, SC to Isle of Palms, SCPlan the drive back the other way.
Explore more options from Isle of Palms, SC or browse trips ending in Anderson County Airport, SC.
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