Puerto Vallarta Restaurant
Near the start, right off the route
Jeffersonville, Indiana
Hours: 11 am–10 pm
+18122882022
Visit websiteCompiled and reviewed by the Trip.ovh planning team at COD Solutions Oy · Last reviewed Apr 18, 2026 · Editorial standards
Drive Time
3h 18m
Distance
167.2 mi
269 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$26
one way
EV Charging
Unknown
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Jeffersonville, IN
Wikimedia Commons
Hamilton, IN
Petra Reid
The drive from Jeffersonville, IN to Hamilton, IN covers 167.2 miles and takes about 3h 18m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on I 65, SR 39, Rossville Avenue for much of the mileage, and the overall profile is mostly highway. The longest uninterrupted segment is about 144.4 miles on I 65. At current regular gas prices, budget about $26.14 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
83.6 miles from Jeffersonville, IN
A natural place for your longest stop of the day , about 1h 34m into the drive .
| Road | Distance | Duration |
|---|---|---|
| I 65 | 144.4 mi | 2h 42m |
| SR 39 | 11.5 mi | 16m |
| Rossville Avenue | 4.6 mi | 6m |
| West County Road 400 North | 2.7 mi | 4m |
| IN-47 | 1.8 mi | 3m |
| West Kyger Street | 0.5 mi | <1m |
| East Court Avenue | 0.4 mi | 1m |
| 6th Street | 0.3 mi | <1m |
Step-by-step road directions between Jeffersonville, IN and Hamilton, IN.
Start on Watt Street
Turn right onto East Court Avenue
Turn slight right onto 6th Street
Take the ramp
Merge onto I 65
Keep slight right at fork onto I 65
Take the exit onto US 52
Keep slight left at fork
Merge onto I 65
Take the exit
Turn right onto SR 47
Turn left onto SR 39
Turn left onto US 421; SR 39
Turn slight right onto US 421; SR 39
Turn left onto SR 38
Turn right onto North County Road 600 West
Arrive at destination
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 37 miles or 42m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 83.6 miles or 1h 34m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 35m
Traffic, exits, and arrival timing usually matter more near Hamilton, IN than in the middle of the route.
Open the route before leaving Jeffersonville, IN so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Jeffersonville, IN
This is one driving day of about 167.2 miles and 3h 18m.
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
84 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 37 miles helps settle the day before fatigue starts building.
The midpoint is around 83.6 miles from Jeffersonville, IN, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before I 65 if your tank is already low. That segment runs about 144.4 miles.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Restaurants, cafes, gas stations and more along your route.
Top Restaurant
Jeffersonville, Indiana
Near the start, right off the route
Hours: 11 am–10 pm
+18122882022
Pines
Seymour, IN
City Barbeque
Whitestown, Indiana
Top Coffee Stop
Jeffersonville, Indiana
Near the start, right off the route
Hours: 7 am–10 pm
+18129200926
Coffee Crossing
Jeffersonville, Indiana
Quills Coffee
Louisville, Kentucky
Near the start, right off the route
Jeffersonville, Indiana
Hours: 11 am–10 pm
+18122882022
Visit websiteEarly in the drive, right off the route
Seymour, IN
Hours: Closed
+18125224955
Visit websiteLater in the drive, short detour
Whitestown, Indiana
Hours: 10:30 am–9 pm
+13179730430
Visit websiteLater in the drive, right off the route
Indianapolis, Indiana
Hours: 9 am–11 pm
+13179867554
Visit websiteLater in the drive, short detour
Indianapolis, Indiana
Hours: 11 am–12 pm
+13173889788
Visit websiteNear the start, short detour
Louisville, Kentucky
Hours: 12–2:30 pm
+15027423358
Visit websiteNear the start, short detour
Louisville, Kentucky
Hours: 11:30 am–1:30 pm
+15025801350
Visit websiteNear the start, short detour
Louisville, Kentucky
Hours: 11 am–3 pm
+15025811011
Visit websiteNear the start, right off the route
Jeffersonville, Indiana
Hours: 7 am–10 pm
+18129200926
Visit websiteNear the start, right off the route
Jeffersonville, Indiana
Hours: 6:30 am–8 pm
+18125903867
Visit websiteNear the start, short detour
Louisville, Kentucky
Hours: 6 am–7 pm
+15028615844
Visit websiteNear the start, short detour
Louisville, Kentucky
Hours: 7 am–5:30 pm
+15025530113
Visit websiteNear the start, short detour
Louisville, Kentucky
Hours: 7:30 am–3 pm
+15025893222
Visit websiteNear the start, short detour
Louisville, Kentucky
Hours: 6:30 am–2:30 pm
+15022943728
Visit websiteNear the start, short detour
Louisville, Kentucky
Hours: 7 am–4 pm
+15022903729
Visit websiteNear the start, short detour
Louisville, Kentucky
Hours: 7 am–5 pm
+15025690000
Visit websiteNear the start, right off the route
Jeffersonville, Indiana
Hours: 10 am–3 pm
+18122833728
Visit websiteNear the start, short detour
Jeffersonville, Indiana
Hours: 2–8 pm
+18127251046
Visit websiteNear the start, short detour
Louisville, Kentucky
Hours: 10 am–5 pm
+15025849254
Visit websiteNear the start, short detour
Louisville, Kentucky
Hours: 9 am–5 pm
+18777758443
Visit websiteNear the start, short detour
Louisville, Kentucky
Hours: 10 am–4 pm
+15025845353
Visit websiteEarly in the drive, short detour
Seymour, Indiana
Hours: 11 am–9 pm
+18122711298
Visit websiteLater in the drive, ~9 min detour
Indianapolis, IN
Hours: Open 24 hours
+13174555289
Visit websitePlace data sourced from public business listings. Hours and availability may vary.
5 decision points cluster between mile 0.9 and 145.7 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
Merge onto I 65
Merge point - match speed before joining. Lane positioning matters here
Keep slight right at fork onto I 65
Highway fork - watch signs carefully. Lane positioning matters here
Take the exit onto US 52 toward US 52 West
Exit ramp - move to the correct lane early
Keep slight left at fork
Highway fork - watch signs carefully
Take the exit toward SR 47: Thorntown, Sheridan
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Regular Gas
$26.14 one way
$52.28 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.36 | $28.70 | $57.40 |
| premium | $4.89 | $32.18 | $64.35 |
| diesel | $5.61 | $36.92 | $73.83 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$26
Meals
$25–$50
Total
$51–$76
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 58.5 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $18 in charging · 0 stops · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 50.2 | 0 | $17.56 | $8.03 |
| Efficient EV | 41.8 | 0 | $14.63 | $6.69 |
| EV Truck/SUV | 66.9 | 0 | $23.41 | $10.70 |
Gas CO2
59 kg
EV CO2
20 kg (66% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Afternoon in Jeffersonville on Saturday
Local time
4:04 PM
EDT
Current temp
76°F
Unavailable
Destination
Afternoon in Hamilton on Saturday
Local time
4:04 PM
EDT
Current temp
53°F
Unavailable
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
167.2 mi in 3h 18m, mostly highway — 144.4 mi of that is on I 65.
This is a straightforward highway drive that stays mostly on I 65 and SR 39. You will hit about 12 points where you need to pay attention to lane position or signs. The trickiest moment comes around 0.9 miles in near I 65.
Moderate - straightforward overall, but long enough or busy enough to require pacing
Balances navigation complexity with total wheel time.
This drive requires moderate attention. Across 167.2 miles you will encounter 12 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: at 0.9 miles (I 65): Merge point - match speed before joining. Lane positioning matters here; at 111.9 miles (I 65): Highway fork - watch signs carefully. Lane positioning matters here; at 141.7 miles (US 52): Exit ramp - move to the correct lane early.
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Jeffersonville, IN to Hamilton, IN, road signs begin pointing toward Sheridan along the way.
Sheridan
Weekend Trip
Doable as a same-day drive at 3h 18m. Total distance: 167.2 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
3h 18m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (95%). Some complex stretches to watch for.
Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.
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