The drive from Joplin, MO to Mexico, MO covers 252.2 miles and takes about 4h 53m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on Congressman Gene Taylor Highway, US 54, MO 5 for much of the mileage,
and the overall profile is mixed drive.
The longest uninterrupted segment is about 113.3 miles on Congressman Gene Taylor Highway.
At current regular gas prices, budget about $39.43 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
126.1 miles from Joplin, MO
A natural place for your longest stop of the day
, about 2h 26m into the drive
.