Origin
Lady Lake, FL
Afternoon in Lady Lake on Saturday
Local time
1:40 PM
EDT
Current temp
59°F
Unavailable
Live forecast
Trip from Lady Lake, FL to Gainesville, FL
Compiled and reviewed by the Trip.ovh planning team at COD Solutions Oy · Last reviewed Apr 18, 2026 · Editorial standards
Drive Time
1h 23m
Distance
64.8 mi
104 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$10
one way
EV Charging
Good
8 stations
Best Time to Leave
4 AM
1h 17m
★
6 AM
1h 23m
8 AM
1h 36m
10 AM
1h 28m
12 PM
1h 27m
3 PM
1h 29m
5 PM
1h 36m
8 PM
1h 20m
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Lady Lake, FL
Wikimedia Commons
Trip Overview
Lady Lake to Gainesville is 64.8 miles and takes about 1 hour 23 minutes via I-75 and US-441, with a fuel budget near $10 and enough daylight to finish in a day. This straightforward drive keeps you within the state of Florida for the entire journey. Expect a route that's primarily focused on highway travel, making it a convenient option for a quick connection between these two central Florida locations. It's a route best suited for those prioritizing efficiency and ease of navigation over extensive sightseeing.
Main Roads
| Road | Distance | Duration |
|---|---|---|
| I 75 | 33.7 mi | 36m |
| Citrus Boulevard | 10 mi | 15m |
| US 441 | 8 mi | 9m |
| CR 484 | 5.4 mi | 7m |
| Southeast 132nd Street Road | 2.8 mi | 4m |
| South Main Street | 2.4 mi | 4m |
| Southeast County Road 234 | 1.3 mi | 2m |
| Southwest Williston Road | 0.5 mi | 1m |
Longest stretch:
I 75
— 33.7 mi, about 36m
Turn-by-Turn Driving Directions
Step-by-step road directions between Lady Lake, FL and Gainesville, FL.
1
Start on CR 466
55 ft
·
1 sec
·
CR 466
2
Turn left onto US 27; US 441
10 mi
·
15 min
·
Citrus Boulevard
3
Turn left onto Southeast 132nd Street Road
2.8 mi
·
4 min
·
Southeast 132nd Street Road
Use the left lane.
4
Continue on CR 484
0.4 mi
·
37 sec
·
CR 484
Use the straight / right lanes.
5
Continue on CR 484
5.0 mi
·
7 min
·
CR 484
Use the straight / right lanes.
6
Take the ramp
0.3 mi
·
43 sec
Toward I 75 North: Ocala
7
Merge onto I 75
34 mi
·
36 min
·
I 75
Use the straight / slight right lanes.
8
Take the exit
0.2 mi
·
31 sec
Exit 374
Toward CR 234: Micanopy
Use the straight / slight right lanes.
9
Turn right onto CR 234
1.3 mi
·
2 min
·
Southeast County Road 234
10
Turn left
421 ft
·
15 sec
Use the left lane.
11
Turn straight onto US 441
8.0 mi
·
9 min
·
US 441
Use the straight lane.
12
Turn right onto FL 331
0.5 mi
·
1 min
·
Southwest Williston Road
Use the right lane.
13
Turn left onto CR 329
1.6 mi
·
2 min
·
South Main Street
14
Enter roundabout onto CR 329
92 ft
·
1 sec
·
South Main Street
15
Continue on CR 329
0.2 mi
·
32 sec
·
South Main Street
16
Enter roundabout onto CR 329
177 ft
·
3 sec
·
South Main Street
17
Continue on CR 329
0.5 mi
·
1 min
·
South Main Street
Use the straight / right lanes.
18
Arrive at destination
CR 329
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
32 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
Pacing Suggestions
Fuel and coffee
A short stop after about 14 miles helps settle the day before fatigue starts building.
Meal break
The midpoint is around 32.4 miles from Lady Lake, FL, which is a good place for a longer meal and fuel stop.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Heads-up: tricky spots
5 of 125 decision points cluster between mile 18.5 and 64.3 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
5
18.5 mi into trip
|
~28m in
|
I 75
Merge onto I 75
Merge point - match speed before joining. Lane positioning matters here
Use the straight / slight right lanes.
7
52.3 mi into trip
|
~1h 4m in
Take the exit toward CR 234: Micanopy
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the straight / slight right lanes.
Exit 374
Toward CR 234: Micanopy
5
53.8 mi into trip
|
~1h 7m in
Turn left
Lane positioning matters here
Use the left lane.
5
61.9 mi into trip
|
~1h 17m in
|
FL 331 / Southwest Williston Road
Turn right onto FL 331 / Southwest Williston Road
Lane positioning matters here
Use the right lane.
5
64.3 mi into trip
|
~1h 22m in
|
CR 329 / South Main Street
Enter roundabout onto CR 329 / South Main Street
Roundabout - know your exit number before entering
Fuel & Cost
Regular Gas
$10.31 one way
$20.63 round trip
$4.04/gal
25.4 MPG avg
23 kg CO2
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.40 | $11.22 | $22.44 |
| premium | $4.72 | $12.05 | $24.10 |
| diesel | $5.61 | $14.31 | $28.61 |
No toll roads detected on this route.
Drive Cost (one way)
Fuel
$10
Estimated CO2 emission: 22.7 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $7 in charging · 0 stops · 65% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 19.4 | 0 | $6.80 | $3.11 |
| Efficient EV | 16.2 | 0 | $5.67 | $2.59 |
| EV Truck/SUV | 25.9 | 0 | $9.07 | $4.15 |
Gas CO2
23 kg
EV CO2
8 kg (65% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Destination
Gainesville, FL
Afternoon in Gainesville on Saturday
Local time
1:40 PM
EDT
Current temp
81°F
Unavailable
Live forecast
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
22 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
1h 23m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
What kind of drive is this?
This trip is a highway-focused drive, with 73% of the route utilizing major highways like I-75. You'll experience a significant uninterrupted stretch of 33.7 miles on I-75, which offers a consistent pace. While the majority is highway, the introduction of Citrus Boulevard and US-441 means you'll transition to more direct, though still efficient, state roads as you approach your destination. It’s a drive that balances interstate speed with more localized access.
73% highway — fuel and pacing are the main things to plan.
18 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 33.7 mi on I 75.
How Hard Is This Drive?
5/10
This is a straightforward highway drive that stays mostly on I 75 and Citrus Boulevard. You will hit about 12 points where you need to pay attention to lane position or signs. The trickiest moment comes around 18.5 miles in near I 75.
Driving Effort
5/10
Moderate - straightforward overall, but long enough or busy enough to require pacing
Balances navigation complexity with total wheel time.
This drive requires moderate attention. Across 64.8 miles you will encounter 12 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: at 18.5 miles (I 75): Merge point - match speed before joining. Lane positioning matters here; at 52.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here; at 53.8 miles: Lane positioning matters here.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Lady Lake, FL to Gainesville, FL, road signs begin pointing toward Cr 234: Micanopy along the way.
Cr 234: Micanopy
52.3 mi in
|
~1h 4m
About the Cities
Arriving in Gainesville, FL
Full guide →Gainesville is in North Central Florida. It is home to the University of Florida, and Santa Fe College.
City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 1h 23m. Total distance: 64.8 miles.
Family Friendly
Moderate complexity with 0 natural rest stops along the way.
Solo Traveler
1h 23m drive, comfortable solo distance.
EV Driver
0 DC fast chargers along the route. Coverage: unknown.
First-Time Driver
Mostly highway driving (73%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 33.7 miles on I 75. The full list of main roads is in the Roads section above.
Yes. At under 2 hours behind the wheel, this works well for families — plan one quick stop if you have younger kids.
The main spots that need attention: at 18.5 miles (I 75): Merge point - match speed before joining. Lane positioning matters here; at 52.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here; at 53.8 miles: Lane positioning matters here.
Yes. A round trip is manageable in a single day if you plan a break at Gainesville, FL before heading back.
How this page is built
Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.
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