Origin
Laredo, TX
Late night in Laredo on Saturday
Local time
3:02 AM
CDT
Current temp
71°F
Forecast unavailable right now
Drive Time
9h 2m
Distance
501.8 mi
Route Type
Long-distance drive
Overnight routeThe drive from Laredo, TX to Anthony, TX covers 501.8 miles and takes about 9h 2m behind the wheel. It usually feels better as a 2-day road trip than as one long push.
The route leans on San Dario Avenue, Purple Heart Trail, South Pan Am Expressway for much of the mileage, and the overall profile is long-distance drive. At current regular gas prices, budget about $74.66 one way before food or hotel costs.
Trip Pace
Best split across 2 days
Treat the return leg as its own travel day rather than an afterthought.
Break Rhythm
2 planned breaks
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
250.9 miles from Laredo, TX
A natural place for your longest stop of the day , about 4h 31m into the drive .
At 501.8 miles and 9h 2m of driving, this is a route where fuel stops, weather, and timing matter more than any single turn. The main roads are San Dario Avenue and Purple Heart Trail.
| Road | Distance | Duration |
|---|---|---|
| San Dario Avenue | Unavailable | Refreshing |
| Purple Heart Trail | Unavailable | Refreshing |
| South Pan Am Expressway | Unavailable | Refreshing |
| North Pan Am Expressway | Unavailable | Refreshing |
| Highway 35 | Unavailable | Refreshing |
| South Jack Kultgen Expressway | Unavailable | Refreshing |
| I 35E | Unavailable | Refreshing |
| I 30 East | Unavailable | Refreshing |
Per-road distance and duration are being refreshed from OSRM for this route.
Step-by-step road directions between Laredo, TX and Anthony, TX.
Start on Matamoros Street
Turn left onto San Dario Avenue
Continue on Purple Heart Trail
Continue on South Pan Am Expressway
Keep slight left to continue on South Pan Am Expressway
Keep slight right to continue on South Pan Am Expressway
Keep slight left to continue on North Pan Am Expressway
Continue on Purple Heart Trail
Continue on Interstate Highway 35
Continue on Purple Heart Trail
Keep slight right to continue on Purple Heart Trail
Continue on South Jack Kultgen Expressway
Continue on Purple Heart Trail
Keep slight right to continue on I 35E: Dallas
Take the exit slight right toward I 30 East: Texarkana, Riverfront Boulevard, Griffin Street
Keep slight left to continue on I 35E North, I 30 West: Denton, Fort Worth, Texarkana
Keep slight right to continue on I 30 East: Texarkana, Convention Center
Keep slight left to continue on I 30 East: Texarkana
Continue on East R L Thornton Freeway
Take the exit slight right toward I 45, US 75: Houston, McKinney
Keep slight left to continue on US 75 North: McKinney
Keep slight right to continue on US 75 North: McKinney, Bryan Street East
Merge slight left onto Julius Schepps Freeway
Continue on North Central Expressway
Take the exit slight right toward TX 121 North: Bonham
Continue on Sam Rayburn Highway
Take the exit slight right toward TX 160: Whitewright, Blue Ridge
Turn left onto State Highway 160
Continue straight
Turn right onto Ole Ambrose Road
Turn right
Arrive at your destination
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
Consider an overnight stop or starting very early.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 110 miles or 1h 58m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 250.9 miles or 4h 31m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Overnight split
Day 1 wrap after about 250.9 miles or 4h 31m
Stop before fatigue turns the last few hours into a grind. You want day two to start fresh, not just resumed.
Final approach
Final hour starts around 7h 57m
Traffic, exits, and arrival timing usually matter more near Anthony, TX than in the middle of the route.
Open the route before leaving Laredo, TX so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Pick one backup stop option before the midpoint in case traffic changes your pacing.
Treat this as a 2-day road trip and book the overnight stop before the busiest arrival window.
Day 1
Settle into the route from Laredo, TX
Aim for roughly 251 miles and 4.5 hours of wheel time on this day.
Day 2
Finish the approach into Anthony, TX
Aim for roughly 251 miles and 4.5 hours of wheel time on this day.
These towns line up with the pace of this drive and give you clearer places to stop with a purpose.
Late stop town
Coffee and fuel
166 mi into the route
Best for: Coffee, fuel, and an easy first stretch
This is a natural early stop once the first hours of the drive are behind you.
Late stop town
Overnight candidate
331 mi into the route
Best for: Hotel check-in, dinner, and a fresh start
This lines up well with a realistic day-end stop if you are breaking the drive into stages.
Night 1
251 mi · about 4.5h in
A practical overnight split lands near Killeen, TX after about 251 miles or 4.5 hours of driving.
Halfway Point
Midpoint
About 250.9 mi from Laredo, TX
A short stop after about 110 miles helps settle the day before fatigue starts building.
The midpoint is around 250.9 miles from Laredo, TX, which is a good place for a longer meal and fuel stop.
Overnight split
Hotel stopFor a steadier pace, wrap day one after about 251 miles or 4.5 hours on the road.
These stop ideas are pacing suggestions for the drive, so the exact town or exit can change with traffic, hotel plans, and fuel range.
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| regular | $3.78 | $74.66 | $149.32 |
| midgrade | $4.25 | $84.00 | $168.00 |
| premium | $4.59 | $90.70 | $181.40 |
| diesel | $3.99 | $78.89 | $157.77 |
Based on 25.4 MPG average. Estimated CO2 emission: 175.6 kg one way.
Travel Intel
Compare the departure city with the arrival city before you leave so the route feels predictable, not reactive.
Origin
Late night in Laredo on Saturday
Local time
3:02 AM
CDT
Current temp
71°F
Forecast unavailable right now
Destination
Late night in Anthony on Saturday
Local time
3:02 AM
CDT
Current temp
58°F
Forecast unavailable right now
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
This is long enough that the arrival forecast matters almost as much as departure conditions. Recheck both ends before you roll.
Continue From Anthony, TX
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