Origin
Liberty, MO
Afternoon in Liberty on Wednesday
Local time
1:25 PM
CDT
Current temp
56°F
Unavailable
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Drive Time
4h 13m
Distance
218.2 mi
351 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$34
one way
EV Charging
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station data
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Liberty, MO
Wikimedia Commons
O'Fallon, MO
Wikimedia Commons
This 218.2-mile journey from Liberty, MO to O'Fallon, MO will take approximately 4 hours and 13 minutes. Primarily following the Dwight D. Eisenhower Highway and U.S. Submarine Veterans' Memorial Highway, this route is best suited for a single day trip, with an estimated fuel cost of $34. You'll experience a 'turn-heavy local drive' feel for much of the way, making it a straightforward trip within the Midwest. This drive offers a practical way to get from point A to point B without extensive planning.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
109.1 miles from Liberty, MO
A natural place for your longest stop of the day , about 2h 5m into the drive .
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Expect a 'turn-heavy local drive' profile for most of this 218.2-mile route. While 6% of the drive utilizes highway travel, the majority involves navigating local roads and highways like MO 291. Your longest uninterrupted stretch will be 142.5 miles on the Dwight D. Eisenhower Highway, offering a period of more consistent travel before transitioning back to more frequent turns. This road personality suggests you'll be more engaged with the driving, with frequent changes in direction and speed.
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. You will hit about 11 points where you need to pay attention to lane position or signs. The trickiest moment comes early in the drive near South Missouri Street.
Moderate - straightforward overall, but long enough or busy enough to require pacing
This drive requires moderate attention. Across 218.2 miles you will encounter 11 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: near the start (South Missouri Street): Navigation decision point; at 0.1 miles (East Mill Street): Navigation decision point; at 14.9 miles: Exit ramp - move to the correct lane early. Lane positioning matters here.
These are the spots where you need to pay the most attention. Preview them before you drive.
Turn right onto South Missouri Street
Navigation decision point
Turn left onto East Mill Street
Navigation decision point
Take the exit toward I 70 East: Saint Louis
Exit ramp - move to the correct lane early. Lane positioning matters here
Take the exit toward MO K: O'Fallon
Exit ramp - move to the correct lane early. Lane positioning matters here
Keep slight right at fork onto Drennen Parkway toward MO K: O'Fallon
Highway fork - watch signs carefully
| Road | Distance | Duration |
|---|---|---|
| Dwight D. Eisenhower Highway | 142.5 mi | 2h 42m |
| U.S. Submarine Veterans' Memorial Highway | 54.4 mi | 58m |
| MO 291 | 14 mi | 20m |
| Sheriff Roger I. Wilson Memorial Highway | 1.9 mi | 2m |
| Highway Patrol Sgt. Benjamin Booth Memorial Highway | 1.6 mi | 1m |
| Truman/Eisenhower Presidential Highway | 1.5 mi | 1m |
| South Leonard Street | 0.6 mi | 1m |
| South Main Street | 0.6 mi | 1m |
Step-by-step road directions between Liberty, MO and O'Fallon, MO.
Start on East Kansas Street
Turn right onto South Missouri Street
Turn left onto East Mill Street
Turn right onto South Leonard Street
Take the ramp
Merge onto MO 291
Take the exit
Merge onto I 70
Continue on I 70
Continue on I 70; US 40
Keep slight left at fork onto I 70
Continue on I 70; US 40
Continue on I 70; US 40
Continue on I 70; US 40
Continue on I 70; US 40
Take the exit
Turn straight onto Drennen Parkway
Keep slight right at fork onto Drennen Parkway
Turn slight left
Continue on South Main Street
Turn right
Arrive at destination
With a total duration of just over 4 hours, this 218.2-mile trip is easily manageable in one day. Consider departing in the morning to maximize daylight and take advantage of potentially lighter traffic. The route has one recommended stop, so plan for a break around the halfway point. Keep an eye on your fuel gauge, as the estimated cost is $34, and be prepared for the 'turn-heavy' nature of the drive, especially as you get closer to your destination in O'Fallon. A specific tip: familiarize yourself with the MO 291 segment, as it's a key artery for this particular journey.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 33m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 109.1 miles or 2h 5m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 26m
Traffic, exits, and arrival timing usually matter more near O'Fallon, MO than in the middle of the route.
Open the route before leaving Liberty, MO so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Liberty, MO
This is one driving day of about 218.2 miles and 4h 13m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 109.1 mi from Liberty, MO · 2h 5m into the drive
Mid-route town
Meal stop
109 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 80 miles helps settle the day before fatigue starts building.
The midpoint is around 109.1 miles from Liberty, MO, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before Dwight D. Eisenhower Highway if your tank is already low. That segment runs about 142.5 miles.
The final approach into O'Fallon, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around O'Fallon, MO.
After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$34.11 one way
$68.23 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.36 | $37.45 | $74.91 |
| premium | $4.89 | $41.99 | $83.98 |
| diesel | $5.61 | $48.18 | $96.35 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$34
Meals
$25–$50
Total
$59–$84
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 76.3 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $23 in charging · 0 stops · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 65.5 | 0 | $22.91 | $10.47 |
| Efficient EV | 54.6 | 0 | $19.09 | $8.73 |
| EV Truck/SUV | 87.3 | 1 | $30.55 | $13.96 |
Gas CO2
76 kg
EV CO2
26 kg (66% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Afternoon in Liberty on Wednesday
Local time
1:25 PM
CDT
Current temp
56°F
Unavailable
Destination
Afternoon in O'Fallon on Wednesday
Local time
1:25 PM
CDT
Current temp
57°F
Unavailable
75°F
Quincy, IL
109 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
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