Trip from Louisville, TN to Memphis, TN

Drive Time

6h 1m

Distance

393.2 mi

Route Type

Turn-heavy local drive

Long day trip

Trip Overview

The drive from Louisville, TN to Memphis, TN covers 393.2 miles and takes about 6h 1m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on Louisville Road, Topside Road, Pellissippi Parkway for much of the mileage, and the overall profile is turn-heavy local drive. At current regular gas prices, budget about $58.38 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

196.6 miles from Louisville, TN

A natural place for your longest stop of the day@if(!empty($enrichment->halfway_point['drive_time'])), about 0m into the drive@endif.

Drive Character

Expect a 6h 1m drive with frequent turns across 393.2 miles of local and secondary roads.

This route has more turning and local-road decision points than a simple highway run.
There are about 21 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Louisville Road is one of the defining roads on this drive.

Main Roads

Road Distance Duration
Louisville Road 0 mi 0m
Topside Road 0 mi 0m
Pellissippi Parkway 0 mi 0m
I 40 West 0 mi 0m
Nashville 0 mi 0m
I 24 West 0 mi 0m
Downtown Loop 0 mi 0m
I 240 West 0 mi 0m
Longest stretch: Louisville Road — 0 mi, about 0m

Step-by-Step Directions

1

Start on Honey Rock Way

2

Turn right onto Louisville Road

3

Turn left onto Topside Road

4

Take the ramp sharp left

5

Merge slight left onto Pellissippi Parkway

6

Take the exit slight right toward I 40 West, I 75 South: Nashville, Chattanooga

7

Keep slight left

8

Merge slight left

9

Keep slight right to continue on Nashville

10

Keep slight right to continue on I 24 West, I 40 West: Nashville

11

Keep slight left to continue on I 40 West: Huntsville, Memphis

12

Merge slight right onto Downtown Loop

13

Continue on Downtown Loop

14

Keep slight left to continue on I 40 West: Memphis

15

Take the exit slight right toward I 240 West, I 40 West: Jackson Mississippi, Little Rock

16

Keep slight right to continue on I 40 West: Little Rock

17

Keep slight left

18

Take the exit slight right toward Second Street, Third Street

19

Continue on North 2nd Street

20

Turn left onto Poplar Avenue

21

Arrive at your destination

When to Leave

Morning Departure

Start early — leave by 6-7 AM to arrive at a reasonable hour.

Evening Departure

This is a long drive — plan for a morning departure or consider splitting it into two days.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 196.6 miles from Louisville, TN, or about 0m into the drive.

This is a comfortable same-day trip.

Drive Plan

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 87 miles or 0m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 196.6 miles or 0m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 0m

Traffic, exits, and arrival timing usually matter more near Memphis, TN than in the middle of the route.

Before You Leave

+

Open the route before leaving Louisville, TN so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Trip Strategy

Day 1

Settle into the route from Louisville, TN

This is one driving day of about 393.2 miles and 6h 1m.

Your first comfortable stop window is around 87 miles from Louisville, TN.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.

Best Stop Towns on This Route

These towns line up with the pace of this drive and give you clearer places to stop with a purpose.

Late stop town

Meal stop

Hendersonville, TN

197 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Travel Advice

Arrival Notes

The final approach into Memphis, TN usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Memphis, TN.

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Stops Along the Way

Halfway Point

Midpoint

About 196.6 mi from Louisville, TN

Johnson, TN

Fuel and coffee

A short stop after about 87 miles helps settle the day before fatigue starts building.

Hendersonville, TN

Meal break

The midpoint is around 196.6 miles from Louisville, TN, which is a good place for a longer meal and fuel stop.

These stop ideas are pacing suggestions for the drive, so the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Fuel Type $/gal One Way Round Trip
regular $3.77 $58.38 $116.75
midgrade $4.25 $65.84 $131.68
premium $4.65 $72.05 $144.09
diesel $5.30 $82.11 $164.22

Based on 25.4 MPG average. Estimated CO2 emission: 137.6 kg one way.

Frequently Asked Questions

The drive from Louisville, TN to Memphis, TN covers 393.2 miles and takes about 6h 1m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are Louisville Road, Topside Road, Pellissippi Parkway. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 196.6 miles from Louisville, TN. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $58.38 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

More trips to Memphis, TN

Next Route Ideas

Explore more options from Louisville, TN or browse trips ending in Memphis, TN .

Looking for more statewide routes? Browse TN road trips .

Explore maps and details for Louisville, TN or Memphis, TN on MapSof.net.