The drive from Macclenny, FL to Tampa, FL covers 182.3 miles and takes about 3h 38m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on I 75, Sid Martin Highway, South 6th Street for much of the mileage,
and the overall profile is mixed drive.
The longest uninterrupted segment is about 82.7 miles on I 75.
At current regular gas prices, budget about $29.02 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
91.2 miles from Macclenny, FL
A natural place for your longest stop of the day
, about 1h 57m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 3h 38m. Total distance: 182.3 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
3h 38m drive, comfortable solo distance.
Drive Character
The drive from Macclenny, FL to Tampa, FL covers 182.3 miles and takes about 3h 38m, using a mix of highways and local roads.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 19 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
I 75 is the longest continuous segment at about 82.7 miles.
How Hard Is This Drive?
This route mixes highway mileage with some local-road sections near the start or finish. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 40.1 miles in near US 301 / Sid Martin Highway.
Driving Effort8/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 14 significant decision points across 182.3 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 40.1 miles (US 301 / Sid Martin Highway): Highway fork - watch signs carefully. Lane positioning matters here; at 79.1 miles (FL 326 / Northwest 70th Street): Lane positioning matters here; at 164.9 miles (I 275): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
Critical Maneuvers
5 of 14 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
6
40.1 mi into trip|~53m in|US 301 / Sid Martin Highway
Keep slight left at fork onto US 301 / Sid Martin Highway
Highway fork - watch signs carefully. Lane positioning matters here
Use the left / straight lanes.
6
79.1 mi into trip|~1h 42m in|FL 326 / Northwest 70th Street
Turn right onto FL 326 / Northwest 70th Street
Lane positioning matters here
Use the right lane.
9
164.9 mi into trip|~3h 16m in|I 275
Keep slight right at fork onto I 275 toward I 275 South: Tampa, Saint Petersburg
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Exit 274
Toward I 275 South: Tampa, Saint Petersburg
7
180.8 mi into trip|~3h 35m in
Take the exit toward Downtown East-West
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the straight / slight right lanes.
Exit 45A
Toward Downtown East-West
9
181.4 mi into trip|~3h 36m in
Keep slight left at fork toward Downtown East, Jefferson Street
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight left / slight right lanes.
Toward Downtown East, Jefferson Street
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Macclenny, FL to Tampa, FL, road signs begin pointing toward Saint Petersburg along the way.
Saint Petersburg
164.9 mi in|~3h 16m|via I 275
Main Roads
Road
Distance
Duration
I 75
82.7 mi
1h 28m
Sid Martin Highway
39 mi
48m
South 6th Street
16.2 mi
21m
I 275
15.9 mi
19m
Starke Bypass
13.1 mi
16m
FL 16
10 mi
13m
Northwest 70th Street
1.5 mi
2m
Northwest 77th Street
1.2 mi
2m
Longest stretch:
I 75
— 82.7 mi, about 1h 28m
Turn-by-Turn Driving Directions
Step-by-step road directions between Macclenny, FL and Tampa, FL.
1
Start on FL 228
0.4 mi·58 sec·North 5th Street
2
Turn right onto South Boulevard West
445 ft·23 sec·South Boulevard West
3
Turn left onto FL 121
16 mi·21 min·South 6th Street
4
Turn left onto FL 16
10.0 mi·13 min·FL 16
5
Take the ramp
0.3 mi·38 sec
6
Merge onto US 301 ALT
13 mi·16 min·Starke Bypass
Use the straight / slight right lanes.
7
Keep slight left at fork onto US 301
39 mi·48 min·Sid Martin Highway
Use the left / straight lanes.
8
Turn right onto FL 326
1.5 mi·2 min·Northwest 70th Street
Use the right lane.
9
Continue on FL 326
1.2 mi·2 min·Northwest 77th Street
Use the straight lane.
10
Take the ramp
0.6 mi·1 min
Toward I 75 South: Tampa
11
Merge onto I 75
83 mi·1 hr 28 min·I 75
Use the straight / slight right lanes.
12
Keep slight right at fork onto I 275
16 mi·19 min·I 275
Exit 274Toward I 275 South: Tampa, Saint PetersburgUse the straight / slight right lanes.
13
Take the exit
0.5 mi·49 sec
Exit 45AToward Downtown East-WestUse the straight / slight right lanes.
14
Keep slight right at fork
251 ft·6 sec
15
Keep slight left at fork
0.2 mi·22 sec
Toward Downtown East, Jefferson StreetUse the slight left / slight right lanes.
16
Continue on North Orange Avenue
0.3 mi·46 sec·North Orange Avenue
Use the straight lane.
17
Turn straight onto Pierce Street
0.3 mi·41 sec·Pierce Street
18
Turn right onto US 41 Business; FL 60
0.3 mi·45 sec·East Kennedy Boulevard
19
Arrive at destination
FL 60
Trip Plan
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 91.2 miles from Macclenny, FL, or about 1h 57m into the drive.
The longest continuous stretch on this route runs about 82.7 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 40 miles or 53m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 91.2 miles or 1h 57m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 59m
Traffic, exits, and arrival timing usually matter more near Tampa, FL than in the middle of the route.
Before You Leave
+
Open the route before leaving Macclenny, FL so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Macclenny, FL
This is one driving day of about 182.3 miles and 3h 38m.
Your first comfortable stop window is around 40 miles from Macclenny, FL.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 75 for about 82.7 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 91.2 mi from Macclenny, FL
· 1h 57m into the drive
Station data from NREL Alternative Fuel Stations database.
Driving Electric?
About $19 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
54.7
0
$19.14
$8.75
Efficient EV
45.6
0
$15.95
$7.29
EV Truck/SUV
72.9
0
$25.52
$11.67
Gas CO2
64 kg
EV CO2
21 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Macclenny, FL
Evening
in Macclenny on Friday
Local time
5:24 PM
EDT
Current temp
54°F
Unavailable
Live forecast
Destination
Tampa, FL
Evening
in Tampa on Friday
Local time
5:24 PM
EDT
Current temp
66°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
12 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
3h 38m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Macclenny, FL to Tampa, FL covers 182.3 miles and takes about 3h 38m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are I 75, Sid Martin Highway, South 6th Street. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 91.2 miles from Macclenny, FL. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $29.02 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. A short stop every 2 to 3 hours is enough for this drive.
This is a demanding drive. With 14 significant decision points across 182.3 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 40.1 miles (US 301 / Sid Martin Highway): Highway fork - watch signs carefully. Lane positioning matters here; at 79.1 miles (FL 326 / Northwest 70th Street): Lane positioning matters here; at 164.9 miles (I 275): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
On the drive from Macclenny, FL to Tampa, FL, road signs begin pointing toward Saint Petersburg along the way.
How this page is built
Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, NREL for EV charging, and NPS for national parks. See our methodology for refresh cadence and limitations.
