Drive Time
4h 38m
Distance
292.4 mi
471 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$47
one way
Photo: Mark Stebnicki
The drive from Manteo, NC to Winston-Salem, NC covers 292.4 miles and takes about 4h 38m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on Highway 64, Rolesville Road, Marks Creek Road for much of the mileage, and the overall profile is turn-heavy local drive. At current regular gas prices, budget about $46.80 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
146.2 miles from Manteo, NC
A natural place for your longest stop of the day , about 2h 19m into the drive .
Expect a 4h 38m drive with frequent turns across 292.4 miles of local and secondary roads.
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. There are only a few real navigation decisions along the way.
Easy - simple navigation with a manageable amount of wheel time
This is a straightforward 4h 38m drive. You will face about 0 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
This route does not have any notably tricky sections. Most of the drive from Manteo, NC to Winston-Salem, NC is straightforward, with well-signed roads and simple exits.
| Road | Distance | Duration |
|---|---|---|
| Highway 64 | Unavailable | Refreshing |
| Rolesville Road | Unavailable | Refreshing |
| Marks Creek Road | Unavailable | Refreshing |
| Horton Road | Unavailable | Refreshing |
| Buffaloe Road | Unavailable | Refreshing |
| Northern Wake Expressway | Unavailable | Refreshing |
| US 70 West | Unavailable | Refreshing |
| Glenwood Avenue | Unavailable | Refreshing |
Per-road distance and duration are being refreshed from OSRM for this route.
Step-by-step road directions between Manteo, NC and Winston-Salem, NC.
Start on N US Highway 64
Take the ramp slight right
Merge slight left
Keep slight left
Turn left
Continue straight
Continue straight
Take the exit slight right toward Rolesville Road
Keep slight right to continue on Rolesville Road
Turn right onto Rolesville Road
Turn sharp left onto Marks Creek Road
Turn right onto Horton Road
Turn right onto Buffaloe Road
Take the ramp right
Merge slight left onto Northern Wake Expressway
Take the exit slight right toward US 70 West: Durham
Merge slight left onto Glenwood Avenue
Continue on New Raleigh Highway
Continue on South Miami Boulevard
Keep slight left
Keep slight right
Keep slight right
Keep slight right to continue on Salem Parkway
Take the exit slight right toward Main Street
Turn slight right onto South Main Street
Arrive at your destination
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 16m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 146.2 miles or 2h 19m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 48m
Traffic, exits, and arrival timing usually matter more near Winston-Salem, NC than in the middle of the route.
Open the route before leaving Manteo, NC so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Manteo, NC
This is one driving day of about 292.4 miles and 4h 38m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 146.2 mi from Manteo, NC · 2h 19m into the drive
Mid-route town
Meal stop
146 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 80 miles helps settle the day before fatigue starts building.
The midpoint is around 146.2 miles from Manteo, NC, which is a good place for a longer meal and fuel stop.
The final approach into Winston-Salem, NC usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Winston-Salem, NC.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$46.80 one way
$93.59 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.43 | $50.99 | $101.97 |
| premium | $4.78 | $55.00 | $110.01 |
| diesel | $5.64 | $64.96 | $129.92 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$47
Meals
$25–$50
Total
$72–$97
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 102.3 kg one way. Prices: EIA weekly data, 2026-04-06.
Driving Electric?
About $31 in charging · 1 stop · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 87.7 | 1 | $30.70 | $14.04 |
| Efficient EV | 73.1 | 0 | $25.58 | $11.70 |
| EV Truck/SUV | 117 | 1 | $40.94 | $18.71 |
Gas CO2
102 kg
EV CO2
34 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive. If you're planning ahead, check the forecast closer to your travel date.
Origin
Late night in Manteo on Sunday
Local time
2:19 AM
EDT
Current temp
74°F
Forecast unavailable right now
Destination
Late night in Winston-Salem on Sunday
Local time
2:19 AM
EDT
Current temp
90°F
Forecast unavailable right now
Along the Route
66°F
Raleigh, NC
146 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
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