The drive from Mayo, FL to Fort Lauderdale, FL covers 371.5 miles and takes about 7h 1m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on Florida's Turnpike, I 75, US Highway 27 for much of the mileage,
and the overall profile is highway-focused drive.
The longest uninterrupted segment is about 240.6 miles on Florida's Turnpike.
At current regular gas prices, budget about $59.13 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
2 planned breaks
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
185.8 miles from Mayo, FL
A natural place for your longest stop of the day
, about 3h 33m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 7h 1m. Total distance: 371.5 miles.
Family Friendly
Moderate complexity with 2 natural rest stops along the way.
Solo Traveler
7h 1m drive, plan rest stops for pacing.
Drive Character
This is a 7h 1m highway drive covering 371.5 miles, with most of the trip on Florida's Turnpike and I 75. The longest continuous stretch is about 240.6 miles on Florida's Turnpike.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 20 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Florida's Turnpike is the longest continuous segment at about 240.6 miles.
How Hard Is This Drive?
This is a straightforward highway drive that stays mostly on Florida's Turnpike and I 75. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 46.2 miles in.
Driving Effort7/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 13 significant decision points across 371.5 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 46.2 miles: Lane positioning matters here; at 117.9 miles (Florida's Turnpike): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 358.5 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Critical Maneuvers
5 of 13 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
5
46.2 mi into trip|~1h 2m in
Take the ramp toward I 75 South: Tampa
Lane positioning matters here
Use the straight / slight right lanes.
Toward I 75 South: Tampa
8
117.9 mi into trip|~2h 20m in|Florida's Turnpike
Take the exit onto Florida's Turnpike toward Florida's Turnpike South, Orlando
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight left / straight lanes.
Exit 328
Toward Florida's Turnpike South, Orlando
8
358.5 mi into trip|~6h 39m in
Take the exit toward Coconut Creek Parkway, Martin Luther King Boulevard
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 67
Toward Coconut Creek Parkway, Martin Luther Kin...
6
359.1 mi into trip|~6h 41m in
Keep slight left at fork toward East Martin Luther King Boulevard, Atlantic Boulevard
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward East Martin Luther King Boulevard, Atlan...
8
369.1 mi into trip|~6h 55m in
Take the exit toward SR 842: Broward Boulevard, Downtown
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Exit 27
Toward SR 842: Broward Boulevard, Downtown
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Mayo, FL and Fort Lauderdale, FL, road signs point toward Florida's Turnpike South and Orlando.
Florida's Turnpike South
117.9 mi in|~2h 20m|via Florida's Turnpike
Orlando
117.9 mi in|~2h 20m|via Florida's Turnpike
Main Roads
Road
Distance
Duration
Florida's Turnpike
240.6 mi
4h 19m
I 75
70.8 mi
1h 15m
US Highway 27
40.3 mi
53m
I 95
7.2 mi
8m
ML King Memorial Highway
3.8 mi
4m
West Broward Boulevard
1.8 mi
3m
Dr. Martin Luther King Boulevard
1.4 mi
2m
Santa Fe Boulevard
0.9 mi
1m
Longest stretch:
Florida's Turnpike
— 240.6 mi, about 4h 19m
Turn-by-Turn Driving Directions
Step-by-step road directions between Mayo, FL and Fort Lauderdale, FL.
1
Start on US 27
0.7 mi·1 min·Main Street
2
Continue on US 27
40 mi·53 min·US Highway 27
3
Continue on FL 20
0.6 mi·1 min·Northeast 1st Avenue
4
Turn right onto US 441
0.9 mi·1 min·Santa Fe Boulevard
5
Continue on US 441
3.8 mi·4 min·ML King Memorial Highway
Use the left / straight lanes.
6
Take the ramp
0.8 mi·1 min
Toward I 75 South: TampaUse the straight / slight right lanes.
7
Merge onto I 75
71 mi·1 hr 15 min·I 75
Use the straight lane.
8
Take the exit onto Florida's Turnpike
241 mi·4 hr 19 min·Florida's Turnpike
Exit 328Toward Florida's Turnpike South, OrlandoUse the slight left / straight lanes.
9
Take the exit
0.6 mi·1 min
Exit 67Toward Coconut Creek Parkway, Martin Luther King BoulevardUse the slight right lane.
10
Keep slight left at fork
251 ft·15 sec
Toward East Martin Luther King Boulevard, Atlantic Boulevard
11
Turn left onto Dr. Martin Luther King Boulevard
1.4 mi·2 min·Dr. Martin Luther King Boulevard
Use the left / straight lanes.
12
Turn left onto Northwest 16th Avenue
0.1 mi·25 sec·Northwest 16th Avenue
13
Turn right onto North Andrews Avenue
0.6 mi·1 min·North Andrews Avenue
14
Turn left onto SR 814
497 ft·16 sec·West Atlantic Boulevard
Use the left lane.
15
Take the ramp
0.4 mi·58 sec
Toward I 95 South: Miami
16
Merge onto I 95
7.2 mi·8 min·I 95
Use the straight / slight right lanes.
17
Take the exit
0.5 mi·1 min
Exit 27Toward SR 842: Broward Boulevard, DowntownUse the straight / slight right lanes.
18
Turn left onto SR 842
1.8 mi·3 min·West Broward Boulevard
Use the straight lane.
19
Continue on SR 842
0.2 mi·35 sec·East Broward Boulevard
Use the left lane.
20
Arrive at destination
SR 842
Trip Plan
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
You can normally do this drive in one day.
Plan roughly 2 meaningful breaks for fuel, food, and rest.
The halfway point lands around 185.8 miles from Mayo, FL, or about 3h 33m into the drive.
The longest continuous stretch on this route runs about 240.6 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 82 miles or 1h 41m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 185.8 miles or 3h 33m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 5h 49m
Traffic, exits, and arrival timing usually matter more near Fort Lauderdale, FL than in the middle of the route.
Before You Leave
+
Open the route before leaving Mayo, FL so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
+
Pick one backup stop option before the midpoint in case traffic changes your pacing.
Day 1
Settle into the route from Mayo, FL
This is one driving day of about 371.5 miles and 7h 1m.
Your first comfortable stop window is around 82 miles from Mayo, FL.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 2 real breaks rather than only quick fuel stops.
The longest stretch is on Florida's Turnpike for about 240.6 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 185.8 mi from Mayo, FL
· 3h 33m into the drive
The midpoint is around 185.8 miles from Mayo, FL, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel check
Top up before Florida's Turnpike if your tank is already low. That segment runs about 240.6 miles.
Arriving in Fort Lauderdale, FL
The final approach into Fort Lauderdale, FL usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Fort Lauderdale, FL.
After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Nearby Places
Restaurants, cafes, gas stations and more along your route.
Place data sourced from public business listings. Hours and availability may vary.
Fuel & Cost
Regular Gas
$59.13 one way
$118.27 round trip
$4.04/gal25.4 MPG avg130 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.40
$64.33
$128.65
premium
$4.72
$69.08
$138.16
diesel
$5.61
$82.02
$164.05
Estimated Tolls: $16.84
Florida's Turnpike
(240.6 mi)$16.84
Toll estimates based on average 2024-2025 rates. EZ-Pass/SunPass discounts may lower the actual cost.
Estimated Trip Cost (one way, 1 person)
Fuel
$59
Tolls
$17
Meals
$25–$50
Total
$101–$126
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 130 kg one way.
Prices: EIA weekly data, 2026-04-13.
EV Charging Along Route
6 DC fast chargers
· Coverage: good
EvGateway Charging Station
Reddick, Florida
Other
1 DCFC
Tesla Supercharger
Gainesville, Florida
Tesla
1 DCFC
Tesla Supercharger
Gainesville, Florida
Tesla
1 DCFC
Electric Vehicle Charging Station
Gainesville, Florida
Other
1 DCFC
Tesla Destination Charger
Gainesville, Florida
Tesla Destination
1 DCFC
Blink Charging Station
Reddick, Florida
Blink
1 DCFC
Other: 2
Tesla: 2
Tesla Destination: 1
Blink: 1
Station data from NREL Alternative Fuel Stations database.
Driving Electric?
About $39 in charging
· 1 stop
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
111.5
1
$39.01
$17.83
Efficient EV
92.9
1
$32.51
$14.86
EV Truck/SUV
148.6
1
$52.01
$23.78
Gas CO2
130 kg
EV CO2
43 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Mayo, FL
Night
in Mayo on Friday
Local time
10:06 PM
EDT
Current temp
55°F
Unavailable
Live forecast
Destination
Fort Lauderdale, FL
Night
in Fort Lauderdale on Friday
Local time
10:06 PM
EDT
Current temp
69°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
14 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
7h 1m on the road
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Mayo, FL to Fort Lauderdale, FL covers 371.5 miles and takes about 7h 1m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are Florida's Turnpike, I 75, US Highway 27. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 185.8 miles from Mayo, FL. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $59.13 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.
Plan about 2 meaningful breaks for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 13 significant decision points across 371.5 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 46.2 miles: Lane positioning matters here; at 117.9 miles (Florida's Turnpike): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 358.5 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Between Mayo, FL and Fort Lauderdale, FL, road signs point toward Florida's Turnpike South and Orlando.
How this page is built
Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, NREL for EV charging, and NPS for national parks. See our methodology for refresh cadence and limitations.
