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Trip from Mayodan, NC to Greensboro, NC

Compiled and reviewed by the Trip.ovh planning team at COD Solutions Oy · Last reviewed Apr 17, 2026 · Editorial standards

Drive Time

44m

Distance

27.4 mi

44 km

Drive Score

6/10

Good drive

Same Day?

Yes, doable

Fuel Cost

$4

one way

EV Charging

Unknown

Best Time to Leave

Save up to 11 min
4 AM
0h 40m ★
6 AM
0h 44m
8 AM
0h 51m
10 AM
0h 47m
12 PM
0h 46m
3 PM
0h 47m
5 PM
0h 51m
8 PM
0h 42m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown Mayodan, NC, NC

Mayodan, NC

Emily

Trip Overview

This 27.4-mile drive from Mayodan, NC, to Greensboro, NC, is a quick trip that can easily be completed in about 44 minutes, making it perfect for a single-day excursion. You'll primarily travel on US 220 and I-73, with a significant portion of the journey, 82%, being on highways. The estimated fuel cost for this route is around $4, which is quite economical. Given its short length and highway-focused profile, this drive is ideal for a straightforward commute or a brief regional hop within the Southeast. You won't need to plan for an overnight stay; it's designed for efficiency and ease.

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 44m. Total distance: 27.4 miles.

Family Friendly

Moderate complexity with 0 natural rest stops along the way.

Solo Traveler

44m drive, comfortable solo distance.

EV Driver

0 DC fast chargers along the route. Coverage: unknown.

First-Time Driver

Mostly highway driving (82%). Some complex stretches to watch for.

Drive Character

Expect a highway-centric experience for most of this 44-minute journey. With 82% of the drive on highways like US 220 and I-73, you'll encounter stretches of faster-paced travel. The longest uninterrupted segment you'll navigate is 18.3 miles on US 220, allowing for a consistent cruising speed. While predominantly highway, you will also utilize East Academy Street as part of your route. This profile suggests a drive focused on covering ground efficiently rather than winding scenic byways.

Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 17 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
US 220 is the longest continuous segment at about 18.3 miles.

How Hard Is This Drive?

This is a straightforward highway drive that stays mostly on US 220 and I 73. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes early in the drive near West Main Street.

Driving Effort 8/10

Focused - busy navigation packed into a short drive

Balances navigation complexity with total wheel time.

This is a short but busy drive. With 11 decision points packed into just 27.4 miles, you will need to pay attention to lane changes and exits — but the whole thing is over in 44m.

Where does it get tricky?

The main spots that need attention: near the start (West Main Street): Navigation decision point; near the start (US 220 Business / South 2nd Avenue): Navigation decision point; at 3.9 miles (US 220): Merge point - match speed before joining. Lane positioning matters here.

Critical Maneuvers

5 of 11 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

4
0 mi into trip | ~0m in | West Main Street

Turn right onto West Main Street

Navigation decision point

4
0 mi into trip | ~0m in | US 220 Business / South 2nd Avenue

Turn right onto US 220 Business / South 2nd Avenue

Navigation decision point

5
3.9 mi into trip | ~7m in | US 220

Merge onto US 220

Merge point - match speed before joining. Lane positioning matters here

Use the straight lane.
8
13.9 mi into trip | ~19m in | US 220

Keep slight right at fork onto US 220 toward US 220 South: Greensboro

Highway fork - watch signs carefully. Lane positioning matters here

Use the slight right lane. Exit 119 Toward US 220 South: Greensboro
6
26.7 mi into trip | ~42m in | North Spring Street

Turn right onto North Spring Street

Lane positioning matters here

Use the straight / left / right lanes.

Main Roads

Road Distance Duration
US 220 18.3 mi 29m
I 73 4 mi 4m
East Academy Street 1.2 mi 2m
Highway Street 0.9 mi 1m
South 2nd Avenue 0.8 mi 1m
West Smith Street 0.4 mi 1m
West Decatur Street 0.4 mi <1m
North Spring Street 0.4 mi <1m
Longest stretch: US 220 — 18.3 mi, about 29m

Turn-by-Turn Driving Directions

Step-by-step road directions between Mayodan, NC and Greensboro, NC.

1

Start on this road

70 ft · 7 sec · this road
2

Turn right onto West Main Street

107 ft · 7 sec · West Main Street
3

Turn right onto US 220 Business

0.8 mi · 1 min · South 2nd Avenue
4

Continue on US 220 Business

0.9 mi · 1 min · Highway Street
5

Continue on US 220 Business; NC 704

0.4 mi · 44 sec · West Decatur Street
6

Turn right onto US 220 Business; NC 704

0.2 mi · 31 sec · North Market Street
7

Turn left onto US 311; US 220 Business; NC 704

1.2 mi · 2 min · East Academy Street
8

Take the ramp

0.3 mi · 46 sec
9

Merge onto US 220

5.3 mi · 7 min · US 220
Use the straight lane.
10

Keep slight right at fork onto US 220

0.1 mi · 9 sec · US 220
11

Keep slight right at fork onto US 220

0.5 mi · 41 sec · US 220
12

Keep slight left at fork onto I 73; US 220

4.0 mi · 4 min · I 73; US 220
13

Keep slight right at fork onto US 220

12 mi · 21 min · US 220
Exit 119 Toward US 220 South: Greensboro Use the slight right lane.
14

Continue on West Smith Street

0.4 mi · 1 min · West Smith Street
Use the straight / left lanes.
15

Turn right onto North Spring Street

0.4 mi · 42 sec · North Spring Street
Use the straight / left / right lanes.
16

Turn left onto West Market Street

0.3 mi · 47 sec · West Market Street
17

Arrive at destination

West Market Street

Fuel & Cost

Regular Gas

$4.28 one way

$8.57 round trip

$3.97/gal 25.4 MPG avg 10 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.34 $4.68 $9.37
premium $4.70 $5.07 $10.14
diesel $5.61 $6.05 $12.10

No toll roads detected on this route.

Drive Cost (one way)

Fuel

$4

Estimated CO2 emission: 9.6 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $3 in charging · 0 stops · 70% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 8.2 0 $2.88 $1.32
Efficient EV 6.9 0 $2.40 $1.10
EV Truck/SUV 11 0 $3.84 $1.75

Gas CO2

10 kg

EV CO2

3 kg (70% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 15, 2026

Origin

Mayodan, NC

Late night in Mayodan on Friday

Local time

4:13 AM

EDT

Current temp

48°F

Unavailable

Live forecast

Destination

Greensboro, NC

Late night in Greensboro on Friday

Local time

4:13 AM

EDT

Current temp

72°F

Unavailable

Live forecast

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

24 degrees warmer at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

44m on the road

Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Mayodan, NC to Greensboro, NC covers 27.4 miles and takes about 44m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.

The main roads are US 220, I 73, East Academy Street. Most of the drive stays on highways, so watch for ramps and exits.

This is a comfortable same-day trip.

The midpoint is about 13.7 miles from Mayodan, NC. Look for rest areas, gas stations, or food options near the halfway mark.

At current regular gas prices, expect to spend about $4.28 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.

Leave by 9 AM and you'll arrive before lunch. Even a 4 PM departure gets you there before dark in summer.

This is a short but busy drive. With 11 decision points packed into just 27.4 miles, you will need to pay attention to lane changes and exits — but the whole thing is over in 44m.

The main spots that need attention: near the start (West Main Street): Navigation decision point; near the start (US 220 Business / South 2nd Avenue): Navigation decision point; at 3.9 miles (US 220): Merge point - match speed before joining. Lane positioning matters here.

The route from Mayodan, NC to Greensboro, NC does not surface many named destination signs beyond the main corridor.

How this page is built

Compiled and maintained by the Trip.ovh planning team at COD Solutions Oy (Helsinki). Each route is built from authoritative open government and mapping datasets rather than crowdsourced reviews. Distances and geometry come from OSRM over OpenStreetMap. Fuel cost uses EIA weekly regional averages. Pages are published only after passing our data-quality checks; our methodology page documents refresh cadence, editorial standards, and known limitations.

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