Trip from Medford, OR to Nyssa, OR

Drive Time

10h 14m

Distance

417.7 mi

672 km

Drive Score

7/10

Good drive

Same Day?

2-day trip

Fuel Cost

$83

one way

EV Charging

Loading...

station data

Best Time to Leave

Save up to 27 min
4 AM
10h 5m ★
6 AM
10h 14m
8 AM
10h 32m
10 AM
10h 20m
12 PM
10h 19m
3 PM
10h 21m
5 PM
10h 32m
8 PM
10h 8m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown Medford, OR, OR

Medford, OR

Diana Orey

Trip Overview

The drive from Medford, OR to Nyssa, OR covers 417.7 miles and takes about 10h 14m behind the wheel. It usually feels better as a 2-day road trip than as one long push.

The route leans on West 4th Street, Biddle Road, Crater Lake Highway for much of the mileage, and the overall profile is turn-heavy local drive. At current regular gas prices, budget about $83.13 one way before food or hotel costs.

Trip Pace

Best split across 2 days

Treat the return leg as its own travel day rather than an afterthought.

Break Rhythm

2 planned breaks

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

208.8 miles from Medford, OR

A natural place for your longest stop of the day , about 5h 7m into the drive .

Drive Character

Expect a 10h 14m drive with frequent turns across 417.7 miles of local and secondary roads.

This route has more turning and local-road decision points than a simple highway run.
There are about 43 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
West 4th Street is one of the defining roads on this drive.

How Hard Is This Drive?

Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. There are only a few real navigation decisions along the way.

Route Complexity 4/10

Easy - simple navigation with a manageable amount of wheel time

The route itself is not hard, but at 10h 14m, endurance matters. Plan breaks every 2-3 hours. The 0 decision points are all manageable with basic attention.

Where does it get tricky?

This route does not have any notably tricky sections. Most of the drive from Medford, OR to Nyssa, OR is straightforward, with well-signed roads and simple exits.

Main Roads

Road Distance Duration
West 4th Street Unavailable Refreshing
Biddle Road Unavailable Refreshing
Crater Lake Highway Unavailable Refreshing
Rogue Valley Expressway Unavailable Refreshing
Lake of the Woods Highway Unavailable Refreshing
Falls Highway Unavailable Refreshing
Westside Road Unavailable Refreshing
West Side Road Unavailable Refreshing

Per-road distance and duration are being refreshed from OSRM for this route.

Longest stretch: West 4th Street — detailed segment metrics are refreshing.

Turn-by-Turn Driving Directions

Step-by-step road directions between Medford, OR and Nyssa, OR.

1

Start on North Fir Street

0.1 mi · 18 sec · North Fir Street
2

Turn right onto West 4th Street

0.4 mi · 54 sec · West 4th Street
3

Continue on Biddle Road

1.3 mi · 2 min · Biddle Road
4

Take the ramp right

0.2 mi · 36 sec
5

Merge slight left onto Crater Lake Highway

0.4 mi · 52 sec · Crater Lake Highway
6

Turn straight onto Rogue Valley Expressway

4.5 mi · 6 min · Rogue Valley Expressway
7

At the end of the road, turn left onto Crater Lake Highway

0.5 mi · 39 sec · Crater Lake Highway
8

Turn right onto Lake of the Woods Highway

1.7 mi · 1 min · Lake of the Woods Highway
9

Enter the roundabout and take exit 2 toward Lake of the Woods Highway

121 ft · 2 sec · Lake of the Woods Highway
10

Exit the roundabout onto Lake of the Woods Highway

0.5 mi · 36 sec · Lake of the Woods Highway
11

Keep slight right to continue on Lake of the Woods Highway

30 mi · 34 min · Lake of the Woods Highway
12

Continue on Falls Highway

11 mi · 15 min · Falls Highway
13

Turn left onto Westside Road

0.5 mi · 42 sec · Westside Road
14

Continue on West Side Road

1.3 mi · 1 min · West Side Road
15

Continue on Westside Road

15 mi · 20 min · Westside Road
16

Continue on Sevenmile Road

4.7 mi · 6 min · Sevenmile Road
17

At the end of the road, turn right onto Weed Road East

0.5 mi · 58 sec · Weed Road East
18

Turn left onto Loosley Road

1.5 mi · 2 min · Loosley Road
19

Turn right onto Crater Lake Highway

5.3 mi · 7 min · Crater Lake Highway
20

Turn left onto Chiloquin Highway

3.1 mi · 4 min · Chiloquin Highway
21

Take the ramp left

0.3 mi · 37 sec
22

Merge slight left onto The Dalles-California Highway

20 mi · 22 min · The Dalles-California Highway
23

Turn right onto Silver Lake Road

36 mi · 48 min · Silver Lake Road
24

Continue on Bear Flat Road

15 mi · 20 min · Bear Flat Road
25

Turn right onto Fremont Highway

11 mi · 18 min · Fremont Highway
26

Turn left onto Old Lake Road

15 mi · 20 min · Old Lake Road
27

Turn right onto Christmas Valley Highway

41 mi · 56 min · Christmas Valley Highway
28

At the end of the road, turn left

37 mi · 43 min
29

Continue on Central Oregon Highway

26 mi · 31 min · Central Oregon Highway
30

Continue on Hines Boulevard

0.6 mi · 1 min · Hines Boulevard
31

Continue on West Monroe Street

0.3 mi · 1 min · West Monroe Street
32

Turn left onto North Alvord Avenue

0.4 mi · 1 min · North Alvord Avenue
33

Turn right onto West D Street

282 ft · 18 sec · West D Street
34

Turn left onto North Broadway Avenue

0.1 mi · 38 sec · North Broadway Avenue
35

Turn straight onto Seneca Drive

57 mi · 1 hr 47 min · Seneca Drive
36

Continue on 4th Street

0.3 mi · 1 min · 4th Street
37

Continue on Central Oregon Highway

55 mi · 1 hr 42 min · Central Oregon Highway
38

Continue on A Street West

1.0 mi · 1 min · A Street West
39

Merge slight left onto Central Oregon Highway

11 mi · 12 min · Central Oregon Highway
40

Enter the roundabout and take exit 1 toward Central Oregon Highway

46 ft · 1 sec · Central Oregon Highway
41

Exit the roundabout onto Central Oregon Highway

7.8 mi · 11 min · Central Oregon Highway
42

Continue on Main Street

0.3 mi · 24 sec · Main Street
43

Arrive at your destination

Trip Plan

Morning Departure

Start early — leave by 6-7 AM to arrive at a reasonable hour.

Evening Departure

This is a long drive — plan for a morning departure or consider splitting it into two days.

This drive is better paced as a 2-day trip.
Plan roughly 2 meaningful breaks for fuel, food, and rest.
The halfway point lands around 208.8 miles from Medford, OR, or about 5h 7m into the drive.

Consider an overnight stop or starting very early.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 92 miles or 2h 15m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 208.8 miles or 5h 7m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Overnight split

Day 1 wrap after about 208.8 miles or 5h 7m

Stop before fatigue turns the last few hours into a grind. You want day two to start fresh, not just resumed.

Final approach

Final hour starts around 8h 45m

Traffic, exits, and arrival timing usually matter more near Nyssa, OR than in the middle of the route.

Before You Leave

+

Open the route before leaving Medford, OR so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

+

Pick one backup stop option before the midpoint in case traffic changes your pacing.

+

Treat this as a 2-day road trip and book the overnight stop before the busiest arrival window.

Day 1

Settle into the route from Medford, OR

Aim for roughly 209 miles and 5.1 hours of wheel time on this day.

Day 2

Finish the approach into Nyssa, OR

Aim for roughly 209 miles and 5.1 hours of wheel time on this day.

Your first comfortable stop window is around 92 miles from Medford, OR.
This route usually feels better as a 2-day drive than as one long push.
Plan about 2 real breaks rather than only quick fuel stops.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 208.8 mi from Medford, OR · 5h 7m into the drive

Downtown Bend, OR, OR

Mid-route town

Overnight candidate

Bend, OR

209 mi into the route

Best for: Hotel check-in, dinner, and a fresh start

This lines up well with a realistic day-end stop if you are breaking the drive into stages.

Find hotels in Bend, OR

Overnight Options

Night 1

Bend, OR

209 mi · about 5.1h in

A practical overnight split lands near Bend, OR after about 209 miles or 5.1 hours of driving.

Find hotels

Pacing Suggestions

Rogue River, OR

Fuel and coffee

A short stop after about 92 miles helps settle the day before fatigue starts building.

Bend, OR

Meal break

The midpoint is around 208.8 miles from Medford, OR, which is a good place for a longer meal and fuel stop.

Overnight split

Hotel stop

For a steadier pace, wrap day one after about 209 miles or 5.1 hours on the road.

Arriving in Nyssa, OR

The final approach into Nyssa, OR usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Nyssa, OR.

On a multi-day trip, keep the last day a little lighter so you reach Nyssa, OR with some flexibility left in the schedule.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$83.13 one way

$166.26 round trip

$5.06/gal 25.4 MPG avg 146 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $5.34 $87.78 $175.57
premium $5.59 $91.88 $183.76
diesel $5.64 $92.80 $185.60

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$83

Hotel (1n)

$80–$140

Meals

$50–$100

Total

$213–$323

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 146.1 kg one way. Prices: EIA weekly data, 2026-04-06.

Driving Electric?

About $44 in charging · 1 stop · 66% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 125.3 1 $43.86 $20.05
Efficient EV 104.4 1 $36.55 $16.71
EV Truck/SUV 167.1 2 $58.48 $26.73

Gas CO2

146 kg

EV CO2

49 kg (66% less)

Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast data refreshed 3 days ago

Origin

Medford, OR

Late night in Medford on Monday

Local time

4:37 AM

PDT

Current temp

41°F

Unavailable

Live forecast

Destination

Nyssa, OR

Late night in Nyssa on Monday

Local time

5:37 AM

MDT

Current temp

34°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

For long drives, weather on day two can matter just as much as conditions at departure, so check the whole travel window rather than only the first day.

Time zone

1 hour later

The destination clock does not match departure time, so double-check hotel check-in windows and late arrival plans.

Temperature spread

7 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

10h 14m on the road

This is long enough that the arrival forecast matters almost as much as departure conditions. Recheck both ends before you roll.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Medford, OR to Nyssa, OR covers 417.7 miles and takes about 10h 14m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are West 4th Street, Biddle Road, Crater Lake Highway. Expect a mix of highway and local road driving.
Consider an overnight stop or starting very early.
Yes. This route is usually more comfortable as a 2-day drive. A sensible stopping point is after roughly 209 miles on day one.
The midpoint is about 208.8 miles from Medford, OR. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $83.13 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.
Plan about 2 meaningful breaks for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
The route itself is not hard, but at 10h 14m, endurance matters. Plan breaks every 2-3 hours. The 0 decision points are all manageable with basic attention.
This route does not have any notably tricky sections. Most of the drive from Medford, OR to Nyssa, OR is straightforward, with well-signed roads and simple exits.
The route from Medford, OR to Nyssa, OR does not surface many named destination signs beyond the main corridor.

Was this route helpful?

Thanks for your feedback!

Your tip has been submitted. Thanks!

/500

Explore More

Explore more options from Medford, OR or browse trips ending in Nyssa, OR.

Looking for more statewide routes? Browse OR road trips.

Explore maps for Medford, OR or Nyssa, OR on MapSof.net.