This 352.6-mile journey from Mendon, NY, to Islip, NY, is estimated to take about 7 hours and 30 minutes of driving time. It's a solid day trip, covering ground primarily on I 81, the Keystone Shortway, and the New York State Thruway. With a fuel cost estimated at $58, it's an economical option for a single-day excursion. This route stays within the Northeast region, offering a direct path across New York State. You'll encounter two recommended stops along the way, making it manageable without an overnight stay.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
2 planned breaks
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
176.3 miles from Mendon, NY
A natural place for your longest stop of the day
, about 3h 48m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 7h 30m. Total distance: 352.6 miles.
Family Friendly
Moderate complexity with 2 natural rest stops along the way.
Solo Traveler
7h 30m drive, plan rest stops for pacing.
Scenic Drive
Turn-heavy local drive route profile with national parks nearby.
Drive Character
Expect a drive with a significant amount of highway, accounting for 53% of the total mileage. The personality of this route is best described as 'turn-heavy local drive,' suggesting a mix of faster highway sections and more winding, potentially slower local roads. The longest uninterrupted stretch you'll encounter is 98.8 miles on I 81, providing a good opportunity for steady progress. As you transition between major routes like the New York State Thruway and other highways, the driving experience will evolve, requiring attention to changing road conditions and speed limits.
This route has more turning and local-road decision points than a simple highway run.
There are about 73 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
I 81 is the longest continuous segment at about 98.8 miles.
How Hard Is This Drive?
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 35.3 miles in.
Driving Effort10/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 47 significant decision points across 352.6 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 35.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 185.6 miles (US 6): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 300.1 miles: Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
Critical Maneuvers
5 of 47 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
8
35.3 mi into trip|~42m in
Take the exit toward NY 414: Waterloo, Clyde
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 41
Toward NY 414: Waterloo, Clyde
9
185.6 mi into trip|~3h 59m in|US 6
Keep slight right at fork onto US 6 toward I 84 East, I 380 South, US 6 East: Carbondale, Mt Pocono
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight left / slight right lanes.
Exit 187
Toward I 84 East, I 380 South, US 6 East: Carbo...
8
300.1 mi into trip|~6h 15m in
Keep slight left at fork toward I 95 North: George Washington Bridge, New York City
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Toward I 95 North: George Washington Bridge, Ne...
9
300.4 mi into trip|~6h 15m in
Keep slight right at fork toward Leonia, Teaneck
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 70A-B
Toward Leonia, Teaneck
9
348 mi into trip|~7h 21m in
Take the exit toward Bay Shore Road South, Bay Shore
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 41S
Toward Bay Shore Road South, Bay Shore
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Mendon, NY and Islip, NY, road signs point toward Clyde, Mt Pocono, Milford, New York City, Leonia and Teaneck - among others.
Clyde
35.3 mi in|~42m
Mt Pocono
185.6 mi in|~3h 59m|via US 6
Milford
186.4 mi in|~4h|via I 84; I 380
New York City
300.1 mi in|~6h 15m
Leonia
300.4 mi in|~6h 15m
Teaneck
300.4 mi in|~6h 15m
George Washington Bridge Upper Level
302.7 mi in|~6h 20m
Cross Island Parkway South
321.3 mi in|~6h 46m
Southern State Parkway East
322.8 mi in|~6h 48m
Eastern Long Island
322.8 mi in|~6h 48m
Main Roads
Road
Distance
Duration
I 81
98.8 mi
1h 57m
Keystone Shortway
80 mi
1h 37m
New York State Thruway
30 mi
34m
Southern State Parkway
24.7 mi
31m
I 380
23.6 mi
25m
East Lake Road
9.9 mi
14m
State Highway 41
9.8 mi
13m
Clark Street Road
9.6 mi
11m
Longest stretch:
I 81
— 98.8 mi, about 1h 57m
Turn-by-Turn Driving Directions
Step-by-step road directions between Mendon, NY and Islip, NY.
1
Start on NY 251
2.5 mi·4 min·Victor-Mendon Road
2
Turn left onto Phillips Road
0.8 mi·1 min·Phillips Road
Use the left lane.
3
Turn right onto CR 42
0.4 mi·45 sec·County Road 42
4
Turn left onto NY 96
0.5 mi·44 sec·Victor-Pittsford Road
5
Take the ramp
0.2 mi·23 sec
Toward I 90: New York State Thruway
6
Merge onto I 490
0.3 mi·23 sec·Eastern Expressway
7
Keep slight left at fork
0.6 mi·42 sec
Toward I 90 East: Albany
8
Merge onto I 90
30 mi·34 min·New York State Thruway
9
Take the exit
0.5 mi·58 sec
Exit 41Toward NY 414: Waterloo, ClydeUse the slight right lane.
10
Keep slight right at fork
327 ft·7 sec
11
Continue on NY 414
0.3 mi·35 sec·State Route 414
12
Turn left onto NY 318
4.1 mi·7 min·NY 318
Use the left lane.
13
At end of road, turn left onto US 20; NY 5
1.9 mi·2 min·Auburn Road
14
Continue on US 20; NY 5
9.6 mi·11 min·Clark Street Road
Use the straight lane.
15
Turn right onto State Street
226 ft·12 sec·State Street
16
Turn left onto Dill Street
0.1 mi·21 sec·Dill Street
17
Continue on Loop Road
458 ft·16 sec·Loop Road
18
Turn left onto Genesee Street
5.5 mi·9 min·Genesee Street
19
Continue on US 20
2.2 mi·4 min·West Genesee Street Road
20
Turn right onto NY 41
0.5 mi·45 sec·East Lake Street
21
Continue on NY 41
9.4 mi·13 min·East Lake Road
22
Continue on NY 41
4.8 mi·7 min·State Route 41
23
Continue on NY 41
0.5 mi·49 sec·East Lake Road
24
Continue on NY 41
9.8 mi·13 min·State Highway 41
25
Turn right onto NY 281
1.2 mi·2 min·North West Street
26
Take the ramp
0.7 mi·1 min
Use the left lane.
27
Keep slight right at fork
0.3 mi·34 sec
Toward I 81 South: Binghamton
28
Merge onto I 81
45 mi·54 min·I 81
Use the straight / slight right lanes.
29
Keep slight right at fork onto I 81
53 mi·1 hr 3 min·I 81
Toward I 81 South: ScrantonUse the straight lane.
30
Keep slight right at fork onto US 6
0.8 mi·1 min·US 6
Exit 187Toward I 84 East, I 380 South, US 6 East: Carbondale, Mt PoconoUse the slight left / slight right lanes.
31
Continue on I 84; I 380
3.7 mi·4 min·I 84; I 380
Toward I 84 East, I 380 South: Mount Pocono, MilfordUse the straight lane.
32
Keep slight right at fork onto I 380
24 mi·25 min·I 380
Exit 4Toward I 380 South: Mount Pocono
33
Keep slight left at fork
1.0 mi·1 min
Exit 1BToward I 80 East: Stroudsburg
34
Merge onto I 80
80 mi·1 hr 37 min·Keystone Shortway
Use the straight / right lanes.
35
Keep slight right at fork onto I 80
5.5 mi·5 min·Christopher Columbus Highway
Toward I 95: George Washington Bridge Lower LevelUse the slight right lane.
36
Keep slight left at fork
0.3 mi·23 sec
Toward I 95 North: George Washington Bridge, New York CityUse the straight / slight right lanes.
37
Keep slight right at fork
0.4 mi·38 sec
Exit 70A-BToward Leonia, TeaneckUse the slight right lane.
38
Turn right
0.2 mi·35 sec
Exit 70AToward LeoniaUse the straight / slight right lanes.
39
Turn straight onto CR 56
454 ft·9 sec·Degraw Avenue
40
Continue on CR 56
1.1 mi·2 min·Fort Lee Road
Use the straight / right lanes.
41
Continue on CR 56
469 ft·13 sec·Main Street
42
Take the ramp
472 ft·12 sec
Toward George Washington Bridge
43
Merge onto US 1; US 9; US 46
0.3 mi·28 sec·Bergen Boulevard
Use the straight / slight right lanes.
44
Take the exit
312 ft·4 sec
Toward George Washington Bridge Upper Level
45
Merge onto I 95 EXPR
0.3 mi·20 sec·I 95 EXPR
Use the straight / slight right lanes.
46
Keep slight left at fork onto I 95 EXPR
0.8 mi·1 min·I 95 EXPR
47
Continue on I 95; US 1; US 9
0.6 mi·1 min·George Washington Bridge (upper level)
Use the straight / slight right lanes.
48
Continue on I 95; US 1
0.7 mi·1 min·Trans-Manhattan Expressway
49
Continue on I 95; US 1
4.7 mi·6 min·Cross Bronx Expressway
Use the straight / slight right lanes.
50
Keep slight right at fork onto I 295
2.0 mi·2 min·Cross Bronx Expressway
Exit 6BToward I 295 South: Throgs Neck BridgeUse the straight / slight left lanes.
51
Merge onto I 295
0.6 mi·58 sec·Throgs Neck Expressway
52
Continue on I 295
2.0 mi·3 min·Throgs Neck Bridge
Use the straight / slight right lanes.
53
Continue on I 295
5.0 mi·5 min·Clearview Expressway
Use the straight / slight right lanes.
54
Continue on NY 24
0.7 mi·1 min·Hollis Court Boulevard
Use the straight lane.
55
At end of road, turn left onto NY 24
0.2 mi·35 sec·Jamaica Avenue
Use the left lane.
56
Turn right onto Hempstead Avenue
0.9 mi·2 min·Hempstead Avenue
57
Turn right onto 225th Street
228 ft·9 sec·225th Street
Use the right lane.
58
Take the ramp
0.2 mi·28 sec
Toward Cross Island Parkway South, Verrazano Bridge
59
Merge onto CI
1.3 mi·1 min·Cross Island Parkway
Use the straight / slight right lanes.
60
Take the exit
0.5 mi·1 min
Exit 25AToward Southern State Parkway East, Eastern Long IslandUse the slight left / straight lanes.
61
Merge onto SO
25 mi·31 min·Southern State Parkway
Use the straight / slight right lanes.
62
Keep slight left at fork onto SO
0.2 mi·16 sec·Southern State Parkway
Use the straight / slight right lanes.
63
Take the exit
0.2 mi·31 sec
Exit 41SToward Bay Shore Road South, Bay ShoreUse the slight right lane.
64
Turn straight onto CR 57
0.5 mi·1 min·Bay Shore Road
65
Continue on CR 57
0.3 mi·43 sec·Howells Road
66
Turn straight onto CR 57
341 ft·6 sec·Sunrise Highway
67
Keep slight right at fork onto CR 57
0.6 mi·1 min·Howells Road
Toward Howells Road SouthUse the right lane.
68
Continue on CR 57
0.2 mi·24 sec·Roosevelt Street
69
Continue on CR 57
0.7 mi·1 min·3rd Avenue
70
At end of road, turn left onto NY 27A
1.1 mi·1 min·East Main Street
71
Continue on Montauk Highway
0.2 mi·17 sec·Montauk Highway
72
Continue on NY 27A
0.8 mi·1 min·Main Street
73
Arrive at destination
NY 27A
Trip Plan
To make the most of this 7.5-hour drive, consider an early morning departure from Mendon to maximize daylight hours and avoid potential traffic. With two stops factored in, you can plan for a mid-morning break and a lunch stop, breaking up the 352.6 miles effectively. The longest stretch is nearly 100 miles on I 81, so ensure you're fueled up before entering that section. Given the 'turn-heavy local drive' profile, be prepared for more frequent adjustments and potentially varied speed limits as you navigate different road types.
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
You can normally do this drive in one day.
Plan roughly 2 meaningful breaks for fuel, food, and rest.
The halfway point lands around 176.3 miles from Mendon, NY, or about 3h 48m into the drive.
The longest continuous stretch on this route runs about 98.8 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 78 miles or 1h 47m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 176.3 miles or 3h 48m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 6h 6m
Traffic, exits, and arrival timing usually matter more near Islip, NY than in the middle of the route.
Before You Leave
+
Open the route before leaving Mendon, NY so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
+
Pick one backup stop option before the midpoint in case traffic changes your pacing.
Day 1
Settle into the route from Mendon, NY
This is one driving day of about 352.6 miles and 7h 30m.
Your first comfortable stop window is around 78 miles from Mendon, NY.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 2 real breaks rather than only quick fuel stops.
The longest stretch is on I 81 for about 98.8 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 176.3 mi from Mendon, NY
· 3h 48m into the drive
The midpoint is around 176.3 miles from Mendon, NY, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel check
Top up before I 81 if your tank is already low. That segment runs about 98.8 miles.
Arriving in Islip, NY
The final approach into Islip, NY usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Islip, NY.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
National Parks Near This Route
Worth a detour if your schedule allows.
Hamilton Grange National Memorial
National Memorial
Merchant’s clerk, Revolutionary War soldier, first Secretary Treasury of the United States: Alexander Hamilton’s life is memorialized at The Grange, the home he built on a country estate in uptown Man...
The final resting place of President Ulysses S. Grant and his wife, Julia, is the largest mausoleum in North America. It testifies to a people’s gratitude for the man who ended the bloodiest conflict...
Harriet Tubman was guided by a deep faith and devotion to family, freedom, and community. After emancipating herself and members of her family, she moved them from Ontario, Canada to Fleming and Aubur...
Women’s Rights National Historical Park tells the story of the first Women’s Rights Convention, held in Seneca Falls, New York on July 19-20, 1848. It is a story of struggles for civil rights, human r...
Before the 1960s, almost everything about living authentically as a lesbian, a bisexual person or a gay man was illegal. The Stonewall Uprising on June 28, 1969 is a milestone in the quest for civil r...
The African Burial Ground stands as the oldest and largest known excavated burial site in North America for both free and enslaved Africans. It offers a profound testament to the enduring legacy of Af...
10 mi from route
~25 min detour
Free
near mile 304
Park data from the National Park Service API. Alerts update every 2 hours.
Fuel & Cost
Regular Gas
$58.04 one way
$116.08 round trip
$4.18/gal25.4 MPG avg123 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.52
$62.76
$125.52
premium
$4.92
$68.34
$136.68
diesel
$5.61
$77.85
$155.70
Estimated Tolls: $24.05
George Washington Bridge
$16.00
Throgs Neck Bridge
$6.55
New York State Thruway
(30 mi)$1.50
Toll estimates based on average 2024-2025 rates. EZ-Pass/SunPass discounts may lower the actual cost.
Estimated Trip Cost (one way, 1 person)
Fuel
$58
Tolls
$24
Meals
$25–$50
Total
$107–$132
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 123.4 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $37 in charging
· 1 stop
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
105.8
1
$37.02
$16.92
Efficient EV
88.2
1
$30.85
$14.10
EV Truck/SUV
141
1
$49.36
$22.57
Gas CO2
123 kg
EV CO2
41 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Mendon, NY
Afternoon
in Mendon on Friday
Local time
3:49 PM
EDT
Current temp
44°F
Unavailable
Live forecast
Destination
Islip, NY
Afternoon
in Islip on Friday
Local time
3:49 PM
EDT
Current temp
44°F
Unavailable
Live forecast
57°F
Ramapo, NY
176 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
Very similar conditions
Both ends of the route are sitting at about the same temperature right now.
Road read
7h 30m on the road
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Mendon, NY to Islip, NY covers 352.6 miles and takes about 7h 30m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are I 81, Keystone Shortway, New York State Thruway. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 176.3 miles from Mendon, NY. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $58.04 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.
Plan about 2 meaningful breaks for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 47 significant decision points across 352.6 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 35.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 185.6 miles (US 6): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 300.1 miles: Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
Between Mendon, NY and Islip, NY, road signs point toward Clyde, Mt Pocono, Milford, New York City, Leonia and Teaneck - among others.
Yes. Nearby national parks include Hamilton Grange National Memorial, General Grant National Memorial and Harriet Tubman National Historical Park. There are 6 parks within detour distance of this route.
How this page is built
Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.
