The drive from Meridian, MS to Horn Lake, MS covers 239.1 miles and takes about 4h 41m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on I 22, US 45, US Highway 45 Alternate for much of the mileage,
and the overall profile is highway-focused drive.
The longest uninterrupted segment is about 83.7 miles on I 22.
At current regular gas prices, budget about $33.27 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
119.5 miles from Meridian, MS
A natural place for your longest stop of the day
, about 2h 22m into the drive
.