The drive from Middlebury, IN to Jeffersonville, IN covers 129.6 miles and takes about 3h 2m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on West US Highway 150, SR 37, SR 157 for much of the mileage,
and the overall profile is highway-focused drive.
The longest uninterrupted segment is about 26.8 miles on West US Highway 150.
At current regular gas prices, budget about $20.26 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
64.8 miles from Middlebury, IN
A natural place for your longest stop of the day
, about 1h 38m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 3h 2m. Total distance: 129.6 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
3h 2m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (71%). Some complex stretches to watch for.
Drive Character
This is a 3h 2m highway drive covering 129.6 miles, with most of the trip on West US Highway 150 and SR 37. The longest continuous stretch is about 26.8 miles on West US Highway 150.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 38 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
West US Highway 150 is the longest continuous segment at about 26.8 miles.
How Hard Is This Drive?
This is a straightforward highway drive that stays mostly on West US Highway 150 and SR 37. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 17.1 miles in near SR 157 / North Washington Street.
Driving Effort8/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 26 significant decision points across 129.6 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 17.1 miles (SR 157 / North Washington Street): Navigation decision point; at 118.1 miles (US 150): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 120.4 miles (I 64; US 150): Highway fork - watch signs carefully. Lane positioning matters here.
Critical Maneuvers
5 of 26 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
5
17.1 mi into trip|~29m in|SR 157 / North Washington Street
At end of road, turn right onto SR 157 / North Washington Street
Navigation decision point
6
118.1 mi into trip|~2h 44m in|US 150
Keep slight left at fork onto US 150 toward I 64 East, US 150 East, SR 62 East: New Albany, Louisville
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward I 64 East, US 150 East, SR 62 East: New...
6
120.4 mi into trip|~2h 47m in|I 64; US 150
Keep slight right at fork onto I 64; US 150
Highway fork - watch signs carefully. Lane positioning matters here
Use the straight / slight right lanes.
8
127.5 mi into trip|~2h 57m in
Take the exit toward I 65 South, I 65 Toll North: Nashville, Indianapolis
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight left / straight lanes.
Exit 5
Toward I 65 South, I 65 Toll North: Nashville,...
7
127.6 mi into trip|~2h 57m in
Keep slight right at fork toward I 65 Toll North: Indianapolis
Highway fork - watch signs carefully. Lane positioning matters here
Use the slight right lane.
Toward I 65 Toll North: Indianapolis
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Middlebury, IN to Jeffersonville, IN, road signs begin pointing toward Louisville along the way.
Louisville
118.1 mi in|~2h 44m|via US 150
Main Roads
Road
Distance
Duration
West US Highway 150
26.8 mi
31m
SR 37
26.6 mi
32m
SR 157
12.7 mi
21m
East Main Street
12.4 mi
18m
Southeast Main Street
10.4 mi
14m
SR 45
8.8 mi
12m
Center Street
8.7 mi
13m
I 64
7.1 mi
9m
Longest stretch:
West US Highway 150
— 26.8 mi, about 31m
Turn-by-Turn Driving Directions
Step-by-step road directions between Middlebury, IN and Jeffersonville, IN.
1
Start on West Martz Market Street
0.1 mi·27 sec·West Martz Market Street
2
Turn right onto SR 59; SR 246
1.4 mi·3 min·SR 59; SR 246
3
Continue on SR 157
1.5 mi·2 min·SR 157
4
Turn right onto SR 157
4.4 mi·7 min·SR 157
5
Turn left onto SR 157
0.1 mi·14 sec·Seventh Street
6
Continue on SR 157
2.7 mi·3 min·Hochstetler Street
7
Keep slight right at fork onto SR 157
4.0 mi·6 min·SR 157
8
At end of road, turn left onto SR 157
2.8 mi·5 min·SR 157
9
Turn left onto SR 157
0.2 mi·17 sec·East Main Street
10
At end of road, turn right onto SR 157
102 ft·2 sec·North Washington Street
11
Turn slight right onto US 231; SR 67; SR 157
185 ft·10 sec·South Commercial Street
12
Turn left onto SR 157
0.1 mi·22 sec·Central Avenue
13
At end of road, turn right onto SR 157
0.2 mi·36 sec·Christian Street
14
Continue on Smith Ferry Road
0.2 mi·35 sec·Smith Ferry Road
15
Turn straight onto SR 157
8.7 mi·13 min·Center Street
16
Turn left onto SR 54
12 mi·17 min·East Main Street
17
Turn slight right onto SR 54
1.5 mi·2 min·SR 54
18
At end of road, turn right onto SR 45; SR 54
8.8 mi·12 min·SR 45; SR 54
19
Continue on SR 54; SR 58
5.2 mi·7 min·SR 54; SR 58
20
Turn right onto SR 37; SR 58
14 mi·16 min·SR 37; SR 58
21
Continue on SR 37; SR 60
12 mi·15 min·SR 37; SR 60
22
Enter roundabout onto US 150; SR 56
0.1 mi·8 sec·East Main Street
23
Continue on US 150; SR 56
0.2 mi·14 sec·East Main Street
24
Turn right onto US 150
10 mi·14 min·Southeast Main Street
25
Continue on US 150
27 mi·31 min·West US Highway 150
26
Keep slight left at fork onto US 150
2.3 mi·3 min·US 150
Toward I 64 East, US 150 East, SR 62 East: New Albany, Louisville
27
Keep slight right at fork onto I 64; US 150
7.1 mi·9 min·I 64; US 150
Use the straight / slight right lanes.
28
Take the exit
0.1 mi·15 sec
Exit 5Toward I 65 South, I 65 Toll North: Nashville, IndianapolisUse the slight left / straight lanes.
29
Keep slight right at fork
0.5 mi·59 sec
Toward I 65 Toll North: IndianapolisUse the slight right lane.
30
Merge onto I 65
0.5 mi·45 sec·Abraham Lincoln Bridge
31
Take the exit
0.3 mi·42 sec
Toward Court Avenue, 6th Street
32
Turn right onto West Court Avenue
0.5 mi·1 min·West Court Avenue
33
Turn left onto Walnut Street
221 ft·11 sec·Walnut Street
34
Turn right
204 ft·20 sec
35
Turn left
131 ft·11 sec
36
Turn right
212 ft·17 sec
37
At end of road, turn right onto Watt Street
96 ft·4 sec·Watt Street
38
Arrive at destination
Watt Street
Trip Plan
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 64.8 miles from Middlebury, IN, or about 1h 38m into the drive.
The longest continuous stretch on this route runs about 26.8 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 29 miles or 49m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 64.8 miles or 1h 38m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 30m
Traffic, exits, and arrival timing usually matter more near Jeffersonville, IN than in the middle of the route.
Before You Leave
+
Open the route before leaving Middlebury, IN so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Middlebury, IN
This is one driving day of about 129.6 miles and 3h 2m.
Your first comfortable stop window is around 29 miles from Middlebury, IN.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on West US Highway 150 for about 26.8 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 64.8 mi from Middlebury, IN
· 1h 38m into the drive
The midpoint is around 64.8 miles from Middlebury, IN, which is a good place for a longer meal and fuel stop.
Arriving in Jeffersonville, IN
The final approach into Jeffersonville, IN usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Jeffersonville, IN.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Nearby Places
Restaurants, cafes, gas stations and more along your route.
Top Restaurant
Puerto Vallarta Restaurant
4.3
★ ★ ★ ★ ☆
Jeffersonville, Indiana
Near the end, right off the route
0.4 mi from route
~1 min detour
$10 to $20
mile 129.6
Place data sourced from public business listings. Hours and availability may vary.
Fuel & Cost
Regular Gas
$20.26 one way
$40.52 round trip
$3.97/gal25.4 MPG avg45 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.36
$22.25
$44.49
premium
$4.89
$24.94
$49.88
diesel
$5.61
$28.61
$57.23
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$20
Meals
$25–$50
Total
$45–$70
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 45.3 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $14 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
38.9
0
$13.61
$6.22
Efficient EV
32.4
0
$11.34
$5.18
EV Truck/SUV
51.8
0
$18.14
$8.29
Gas CO2
45 kg
EV CO2
15 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Middlebury, IN
Morning
in Middlebury on Saturday
Local time
7:47 AM
EDT
Current temp
54°F
Unavailable
Live forecast
Destination
Jeffersonville, IN
Morning
in Jeffersonville on Saturday
Local time
7:47 AM
EDT
Current temp
76°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
22 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
3h 2m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Middlebury, IN to Jeffersonville, IN covers 129.6 miles and takes about 3h 2m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are West US Highway 150, SR 37, SR 157. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 64.8 miles from Middlebury, IN. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $20.26 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. A short stop every 2 to 3 hours is enough for this drive.
This is a demanding drive. With 26 significant decision points across 129.6 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 17.1 miles (SR 157 / North Washington Street): Navigation decision point; at 118.1 miles (US 150): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 120.4 miles (I 64; US 150): Highway fork - watch signs carefully. Lane positioning matters here.
On the drive from Middlebury, IN to Jeffersonville, IN, road signs begin pointing toward Louisville along the way.
How this page is built
Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.
