Origin
Missouri City, TX
Evening in Missouri City on Sunday
Local time
7:52 PM
CDT
Current temp
70°F
Unavailable
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Create accountDrive Time
5h 50m
Distance
300.8 mi
484 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$46
one way
EV Charging
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station data
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Missouri City, TX
Mark Direen
Laredo, TX
Jeff Stapleton
If you are planning a trip from Missouri City to Laredo, expect a straightforward journey covering approximately 300.8 miles. You can comfortably complete this drive in about 5 hours and 50 minutes, making it a manageable single-day excursion. Budgeting around $46 for fuel will get you from the Great Plains region of Missouri City to your destination in Laredo. Because the route is relatively direct, you won't need to worry about booking an overnight stay unless you prefer a slower pace. It is a practical, highway-focused drive that connects two distinct points in Texas without unnecessary detours.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
150.4 miles from Missouri City, TX
A natural place for your longest stop of the day , about 2h 55m into the drive .
Expect a consistent, highway-focused experience as 96% of your trip takes place on US 59. This route is defined by its efficiency, featuring a significant 123.9-mile stretch that serves as the longest uninterrupted portion of your journey. You will spend the vast majority of your time on US Highway 59, which provides a steady and predictable rhythm behind the wheel. While the road is not overly technical, the transition across the Great Plains offers a reliable, no-nonsense path. You can settle in for a long, focused drive that prioritizes speed and directness over winding scenic alternatives.
This is a straightforward highway drive that stays mostly on US 59 and US Highway 59. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.1 miles in near FM 2234 / Texas Parkway.
Demanding - plan breaks and stay ahead of the key maneuvers
This is a demanding drive. With 23 significant decision points across 300.8 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 0.1 miles (FM 2234 / Texas Parkway): Navigation decision point; at 0.2 miles: Lane positioning matters here; at 3.5 miles: Exit ramp - move to the correct lane early. Lane positioning matters here.
These are the spots where you need to pay the most attention. Preview them before you drive.
Turn right onto FM 2234 / Texas Parkway
Navigation decision point
Turn left
Lane positioning matters here
Take the exit toward US 59
Exit ramp - move to the correct lane early. Lane positioning matters here
Take the ramp toward US 59 South, I 69 South
Lane positioning matters here. Multiple destination signs - pick the right one
Take the exit toward Spur 10: Cottonwood, Church Road, Hartledge Road
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
On the drive from Missouri City, TX to Laredo, TX, road signs begin pointing toward Spur 10: Cottonwood along the way.
Spur 10: Cottonwood
| Road | Distance | Duration |
|---|---|---|
| US 59 | 123.9 mi | 2h 18m |
| US Highway 59 | 74.7 mi | 1h 22m |
| US Highway 59 West | 65.2 mi | 1h 16m |
| Southwest Freeway | 16.7 mi | 18m |
| US Highway 59 South | 4.4 mi | 4m |
| Clark Boulevard | 3 mi | 5m |
| Main Street | 3 mi | 4m |
| Southwest Freeway Frontage Road | 1.5 mi | 2m |
Step-by-step road directions between Missouri City, TX and Laredo, TX.
Start on this road
Turn right
Turn right onto Orchard Street
Turn right onto 3rd Street
Turn right onto FM 2234
Turn left
Merge onto US 90 Alt
Take the exit
Turn slight left onto Southwest Freeway Frontage Road
Take the ramp
Merge onto I 69; US 59
Take the exit
Turn straight onto Southwest Freeway Frontage Road
Continue on Southwest Freeway Frontage Road
Continue on US 59 Southbound Frontage Road
Take the ramp
Merge onto US 59
Keep slight left at fork onto US 59
Take the exit
Continue on US 59
Keep slight right at fork onto US 59
Take the exit
Continue on Northwest Zac Lenz Parkway Frontage Road East
Turn right onto US 59
Continue on US 59
Continue on US 59
Continue on US 59; TX 44
Turn left onto Bob Bullock Loop
Turn right onto Spur 400
Continue on Park Street
Turn left onto Santa Ursula Avenue
Turn right onto Houston Street
Turn left onto I 35 Bus
Turn left onto Matamoros Street
Arrive at destination
To make the most of your 300.8-mile trek, plan for at least one dedicated stop to break up the nearly six-hour duration. Leaving early in the morning is your best bet to avoid potential traffic and ensure you arrive in Laredo with plenty of daylight to spare. Since the highway makes up such a large share of your travel, keep a close eye on your fuel gauge during the long 123.9-mile stretch where services may be more spread out. Flexibility is a major advantage on this route, so feel free to adjust your pace based on how you feel after the first few hours. Always verify your fuel needs before heading out, as the $46 estimate provides a solid baseline for your planning.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 35m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 150.4 miles or 2h 55m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 47m
Traffic, exits, and arrival timing usually matter more near Laredo, TX than in the middle of the route.
Open the route before leaving Missouri City, TX so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Missouri City, TX
This is one driving day of about 300.8 miles and 5h 50m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 150.4 mi from Missouri City, TX · 2h 55m into the drive
Mid-route town
Meal stop
150 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 80 miles helps settle the day before fatigue starts building.
The midpoint is around 150.4 miles from Missouri City, TX, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before US 59 if your tank is already low. That segment runs about 123.9 miles.
The final approach into Laredo, TX usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Laredo, TX.
After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$45.95 one way
$91.90 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.25 | $50.35 | $100.71 |
| premium | $4.59 | $54.37 | $108.74 |
| diesel | $5.64 | $66.83 | $133.65 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$46
Meals
$25–$50
Total
$71–$96
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 105.2 kg one way. Prices: EIA weekly data, 2026-04-06.
Driving Electric?
About $32 in charging · 1 stop · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 90.2 | 1 | $31.58 | $14.44 |
| Efficient EV | 75.2 | 0 | $26.32 | $12.03 |
| EV Truck/SUV | 120.3 | 1 | $42.11 | $19.25 |
Gas CO2
105 kg
EV CO2
35 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Evening in Missouri City on Sunday
Local time
7:52 PM
CDT
Current temp
70°F
Unavailable
Destination
Evening in Laredo on Sunday
Local time
7:52 PM
CDT
Current temp
71°F
Unavailable
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
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