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Trip from Mosinee, WI to La Crosse, WI

Compiled and reviewed by the Trip.ovh planning team at COD Solutions Oy · Last reviewed Apr 18, 2026 · Editorial standards

Drive Time

3h 1m

Distance

131.7 mi

212 km

Drive Score

9/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$21

one way

EV Charging

Unknown

Best Time to Leave

Save up to 34 min
4 AM
2h 50m ★
6 AM
3h 1m
8 AM
3h 24m
10 AM
3h 9m
12 PM
3h 7m
3 PM
3h 11m
5 PM
3h 23m
8 PM
2h 55m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown Mosinee, WI, WI

Mosinee, WI

Роман Красовский

city in and county seat of La Crosse County, Wisconsin, United States

La Crosse, WI

Wikimedia Commons

Trip Overview

Mosinee to La Crosse is 131.7 miles and takes about 3 hours 1 minute via I 90, with a fuel budget near $21 and enough daylight to finish in a day. This trip stays within Wisconsin, moving from the Midwest region to the Midwest region. It's a straightforward drive, primarily on the interstate, making it a practical choice for a single-day journey. You'll find this route efficient for getting from point A to point B with minimal fuss.

Trip Pace

Same-day drive is realistic

A same-day return is realistic if you keep stops short.

Break Rhythm

1 planned break

A short stop every 2 to 3 hours is enough for this drive.

Midpoint

65.9 miles from Mosinee, WI

A natural place for your longest stop of the day , about 1h 36m into the drive .

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 3h 1m. Total distance: 131.7 miles.

Family Friendly

Moderate complexity with 1 natural rest stops along the way.

Solo Traveler

3h 1m drive, comfortable solo distance.

First-Time Driver

Mostly highway driving (79%). Some complex stretches to watch for.

Drive Character

This is largely a highway-focused drive, with 79% of the route utilizing major highways like I 90. You can expect longer stretches of consistent speed, including one segment of 38.1 miles on I 90 where you'll maintain momentum. While the majority is interstate, there are portions on State Highway 173 and Victory Road that might offer a slight change of pace before returning to faster highway travel. The overall feel is one of steady progress across the landscape.

Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 41 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
I 90 is the longest continuous segment at about 38.1 miles.

How Hard Is This Drive?

This is a straightforward highway drive that stays mostly on I 90 and State Highway 173. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.9 miles in near WI 153 / State Highway 153.

Driving Effort 8/10

Demanding - plan breaks and stay ahead of the key maneuvers

Balances navigation complexity with total wheel time.

This is a demanding drive. With 26 significant decision points across 131.7 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: at 0.9 miles (WI 153 / State Highway 153): Lane positioning matters here; at 5 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 19.3 miles (WI 34): Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one.

Critical Maneuvers

5 of 26 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

5
0.9 mi into trip | ~2m in | WI 153 / State Highway 153

Turn left onto WI 153 / State Highway 153

Lane positioning matters here

Use the straight / right lanes.
6
5 mi into trip | ~7m in

Take the exit toward WI 34: Knowlton, Wisconsin Rapids

Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one

Exit 175 Toward WI 34: Knowlton, Wisconsin Rapids
6
19.3 mi into trip | ~26m in | WI 34

Take the exit onto WI 34 toward WI 34 West, WI 13 South: Wisconsin Rapids

Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one

Exit 204 Toward WI 34 West, WI 13 South: Wisconsin Rapid...
6
85.4 mi into trip | ~2h 3m in

Take the exit toward I 90 West: La Crosse, Albert Lea

Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one

Exit 147 Toward I 90 West: La Crosse, Albert Lea
6
124.2 mi into trip | ~2h 45m in

Take the exit toward WI 16: La Crosse, Onalaska

Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one

Exit 5 Toward WI 16: La Crosse, Onalaska

Towns Mentioned on Route Signs

Based on OSRM destination-sign hints, not a full list of every settlement the road passes.

Between Mosinee, WI and La Crosse, WI, road signs point toward Albert Lea and Onalaska.

Albert Lea

85.4 mi in | ~2h 3m

Onalaska

124.2 mi in | ~2h 45m

Main Roads

Road Distance Duration
I 90 38.1 mi 40m
State Highway 173 34 mi 49m
Victory Road 15.2 mi 22m
State Highway 34 9.9 mi 13m
WI 16 4.9 mi 8m
State Highway 21 4.1 mi 5m
US Highway 10 3.8 mi 4m
I 39 3.3 mi 3m
Longest stretch: I 90 — 38.1 mi, about 40m

Turn-by-Turn Driving Directions

Step-by-step road directions between Mosinee, WI and La Crosse, WI.

1

Start on CTH B

0.6 mi · 1 min · Main Street
Use the straight lane.
2

Turn slight right onto WI 153

425 ft · 18 sec · State Highway 153
3

Turn straight onto WI 153

0.2 mi · 34 sec · Old Highway 51
4

Turn left onto WI 153

0.4 mi · 1 min · State Highway 153
Use the straight / right lanes.
5

Take the ramp

0.3 mi · 43 sec
Toward I 39 South, US 51 South: Stevens Point
6

Merge onto I 39; US 51

3.3 mi · 3 min · I 39; US 51
7

Take the exit

0.3 mi · 38 sec
Exit 175 Toward WI 34: Knowlton, Wisconsin Rapids
8

Keep slight right at fork

199 ft · 6 sec
9

Turn straight onto WI 34

0.2 mi · 16 sec · State Highway 34
10

Enter roundabout onto WI 34; CTH C

123 ft · 2 sec · State Highway 34
11

Continue on WI 34; CTH C

9.7 mi · 13 min · State Highway 34
12

Take the ramp onto WI 34

0.2 mi · 30 sec · WI 34
13

Merge onto US 10; WI 34

3.8 mi · 4 min · US Highway 10
14

Take the exit onto WI 34

0.3 mi · 49 sec · WI 34
Exit 204 Toward WI 34 West, WI 13 South: Wisconsin Rapids
15

Turn left onto WI 13; WI 34

15 mi · 22 min · Victory Road
16

Turn right onto WI 54; WI 73

0.5 mi · 1 min · 2nd Avenue South
17

Enter roundabout onto WI 54; WI 73

185 ft · 3 sec · 2nd Avenue South
18

Continue on WI 54; WI 73

1.3 mi · 1 min · 2nd Avenue South
19

Continue on WI 54; WI 73

1.6 mi · 2 min · Wisconsin River Drive
20

Turn right onto WI 54; WI 73

1.4 mi · 2 min · Letendre Avenue
21

Continue on WI 54

2.1 mi · 3 min · State Highway 54
22

Turn left onto CTH G

2.0 mi · 3 min · County Highway G
23

Continue on State Highway 173

9.1 mi · 13 min · State Highway 173
24

At end of road, turn left onto WI 80; WI 173

410 ft · 7 sec · State Highway 80
25

Continue on WI 80; WI 173

1.3 mi · 1 min · State Highway 173
26

Continue on WI 173

24 mi · 33 min · State Highway 173
27

Turn right onto WI 21

4.0 mi · 5 min · State Highway 21
28

Continue on WI 21

0.3 mi · 33 sec · East McCoy Boulevard
Use the straight lane.
29

Continue on WI 21

0.1 mi · 12 sec · State Highway 21
Use the straight lane.
30

Take the exit

0.3 mi · 41 sec
31

Merge onto I 94

2.8 mi · 2 min · I 94
32

Take the exit

0.7 mi · 51 sec
Exit 147 Toward I 90 West: La Crosse, Albert Lea
33

Merge onto I 90

38 mi · 40 min · I 90
34

Take the exit

0.3 mi · 41 sec
Exit 5 Toward WI 16: La Crosse, Onalaska
35

At end of road, turn left onto WI 16

4.9 mi · 8 min · WI 16
36

Continue on Losey Boulevard North

0.5 mi · 1 min · Losey Boulevard North
37

Turn right onto CTH F

0.7 mi · 1 min · Main Street
38

Turn left onto 16th Street South

0.8 mi · 2 min · 16th Street South
39

Turn right onto Johnson Street

0.3 mi · 1 min · Johnson Street
40

At end of road, turn right onto WI 35

326 ft · 11 sec · West Avenue South
41

Arrive at destination

WI 35

Trip Plan

Given the 3-hour duration, this is a perfect one-day trip, so consider leaving in the morning to give yourself ample time. The single recommended stop suggests you can cover a good distance before needing a break. Keep an eye on your fuel, as the estimated cost is $21, and plan your fill-up accordingly, perhaps before the longest stretch on I 90. This route is direct, so you have the flexibility to depart when it's most convenient for you.

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 65.9 miles from Mosinee, WI, or about 1h 36m into the drive.
The longest continuous stretch on this route runs about 38.1 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 29 miles or 41m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 65.9 miles or 1h 36m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 2h 27m

Traffic, exits, and arrival timing usually matter more near La Crosse, WI than in the middle of the route.

Before You Leave

+

Open the route before leaving Mosinee, WI so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Mosinee, WI

This is one driving day of about 131.7 miles and 3h 1m.

Your first comfortable stop window is around 29 miles from Mosinee, WI.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 90 for about 38.1 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 65.9 mi from Mosinee, WI · 1h 36m into the drive

Downtown Dexterville, WI, WI

Mid-route town

Meal stop

Dexterville, WI

66 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Wisconsin Rapids, WI

Fuel and coffee

A short stop after about 29 miles helps settle the day before fatigue starts building.

Norway Ridge, WI

Meal break

The midpoint is around 65.9 miles from Mosinee, WI, which is a good place for a longer meal and fuel stop.

Arriving in La Crosse, WI

The final approach into La Crosse, WI usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around La Crosse, WI.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$20.59 one way

$41.18 round trip

$3.97/gal 25.4 MPG avg 46 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.36 $22.61 $45.21
premium $4.89 $25.34 $50.69
diesel $5.61 $29.08 $58.16

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$21

Meals

$25–$50

Total

$46–$71

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 46.1 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $14 in charging · 0 stops · 67% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 39.5 0 $13.83 $6.32
Efficient EV 32.9 0 $11.52 $5.27
EV Truck/SUV 52.7 0 $18.44 $8.43

Gas CO2

46 kg

EV CO2

15 kg (67% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 15, 2026

Origin

Mosinee, WI

Night in Mosinee on Friday

Local time

9:17 PM

CDT

Current temp

42°F

Unavailable

Live forecast

Destination

La Crosse, WI

Night in La Crosse on Friday

Local time

9:17 PM

CDT

Current temp

66°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

24 degrees warmer at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

3h 1m on the road

Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Mosinee, WI to La Crosse, WI covers 131.7 miles and takes about 3h 1m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.

The main roads are I 90, State Highway 173, Victory Road. Most of the drive stays on highways, so watch for ramps and exits.

This is a comfortable same-day trip.

The midpoint is about 65.9 miles from Mosinee, WI. Look for rest areas, gas stations, or food options near the halfway mark.

At current regular gas prices, expect to spend about $20.59 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.

An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.

Plan about 1 meaningful break for fuel, food, or rest. A short stop every 2 to 3 hours is enough for this drive.

This is a demanding drive. With 26 significant decision points across 131.7 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

The main spots that need attention: at 0.9 miles (WI 153 / State Highway 153): Lane positioning matters here; at 5 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 19.3 miles (WI 34): Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one.

Between Mosinee, WI and La Crosse, WI, road signs point toward Albert Lea and Onalaska.

How this page is built

Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.

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