The drive from Mount Pleasant, SC to Murrells Inlet, SC covers 76.2 miles and takes about 1h 45m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on US 17, Ocean Highway, Johnnie Dodds Boulevard for much of the mileage,
and the overall profile is highway-focused drive.
The longest uninterrupted segment is about 49.4 miles on US 17.
At current regular gas prices, budget about $11.92 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Midpoint
38.1 miles from Mount Pleasant, SC
A natural place for your longest stop of the day
, about 51m into the drive
.