Origin
Myrtle Beach, SC
Afternoon in Myrtle Beach on Sunday
Local time
4:06 PM
EDT
Current temp
65°F
Unavailable
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Create accountDrive Time
4h 49m
Distance
236.9 mi
381 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$38
one way
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Myrtle Beach, SC
Junior Bastos
Spartanburg, SC
Wikimedia Commons
Traveling from the coast to the Upstate, this 236.9-mile journey across South Carolina connects Myrtle Beach to Spartanburg. You should budget approximately 4 hours and 49 minutes of drive time, making this a manageable one-day trip that doesn't strictly require an overnight stay. Expect to spend about $38 on fuel as you transition from the coastal Southeast region toward the interior. The route relies heavily on major thoroughfares, including I-26, the J. Strom Thurmond Freeway, and Church Street. Because it is a straightforward highway-focused drive, it offers a reliable way to cross the state without needing to navigate complex secondary roads.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
118.4 miles from Myrtle Beach, SC
A natural place for your longest stop of the day , about 2h 31m into the drive .
With 81% of the trip spent on highways, you can expect a high-speed, efficient experience behind the wheel. The journey features a significant 78.3-mile stretch on I-26, which serves as the backbone of your travel and allows for steady, uninterrupted cruising. As you move away from the coast, the road environment remains consistent, prioritizing utility and speed over winding backroads. You will find that the personality of this drive is functional and direct, shifting from freeway travel to local navigation once you hit Church Street near your destination. It is the type of route where you can settle into a rhythm quickly, provided you are comfortable with sustained interstate driving.
This is a straightforward highway drive that stays mostly on I 26 and J Strom Thurmond Freeway. You will hit about 12 points where you need to pay attention to lane position or signs. The trickiest moment comes early in the drive near US 17 Business / North Kings Highway.
Moderate - straightforward overall, but long enough or busy enough to require pacing
This drive requires moderate attention. Across 236.9 miles you will encounter 12 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: near the start (US 17 Business / North Kings Highway): Navigation decision point; at 0.4 miles (Alder Street): Navigation decision point; at 148.2 miles: Exit ramp - move to the correct lane early.
These are the spots where you need to pay the most attention. Preview them before you drive.
At end of road, turn right onto US 17 Business / North Kings Highway
Navigation decision point
At end of road, turn right onto Alder Street
Navigation decision point
Take the exit toward I 26 West
Exit ramp - move to the correct lane early
Keep slight right at fork onto I 26 toward Spartanburg
Highway fork - watch signs carefully. Lane positioning matters here
Take the exit toward US 221: Spartanburg-South, Moore
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
| Road | Distance | Duration |
|---|---|---|
| I 26 | 78.3 mi | 1h 25m |
| J Strom Thurmond Freeway | 76.4 mi | 1h 25m |
| Church Street | 31.2 mi | 39m |
| US 76 | 18.8 mi | 24m |
| US 501 | 10.5 mi | 16m |
| South Church Street | 6 mi | 10m |
| SC 576 | 3.2 mi | 3m |
| West Evans Street | 2.4 mi | 4m |
Step-by-step road directions between Myrtle Beach, SC and Spartanburg, SC.
Start on this road
Turn left
At end of road, turn right onto US 17 Business
Turn left onto 6th Avenue North
Continue on 6th Avenue North
At end of road, turn right onto Alder Street
Turn left onto US 501
Continue on US 501
Continue on US 501
Turn straight onto SC 576
Continue on US 76
Continue on US 76; US 301
Turn slight right onto East Cheves Street
Turn right onto Warley Street
Turn left onto S-21-31
Turn right onto I 20 Bus
Continue on I 20 Bus
Take the exit
Merge onto I 26; US 76
Keep slight right at fork onto I 26
Take the exit
Turn straight onto US 221
Continue on US 221
Arrive at destination
Since this trek spans nearly five hours, consider departing early in the morning to beat potential congestion and arrive in Spartanburg with plenty of daylight left. Planning for at least one stop is essential to break up the monotony of the long highway stretches and keep your focus sharp. Given the $38 estimated fuel cost, check your tank before merging onto I-26 to ensure you aren't forced to stop at higher-priced stations along the interstate. Because you only have one recommended stop, use that time effectively to stretch and refuel rather than rushing back onto the road. The flexibility of this one-day route allows you to adjust your departure time to suit your personal schedule, but keeping a consistent pace will ensure you reach your destination without unnecessary fatigue.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 49m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 118.4 miles or 2h 31m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 57m
Traffic, exits, and arrival timing usually matter more near Spartanburg, SC than in the middle of the route.
Open the route before leaving Myrtle Beach, SC so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Myrtle Beach, SC
This is one driving day of about 236.9 miles and 4h 49m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 118.4 mi from Myrtle Beach, SC · 2h 31m into the drive
Mid-route town
Meal stop
118 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 80 miles helps settle the day before fatigue starts building.
The midpoint is around 118.4 miles from Myrtle Beach, SC, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before I 26 if your tank is already low. That segment runs about 78.3 miles.
The final approach into Spartanburg, SC usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Spartanburg, SC.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$37.91 one way
$75.83 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.43 | $41.31 | $82.62 |
| premium | $4.78 | $44.56 | $89.13 |
| diesel | $5.64 | $52.63 | $105.26 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$38
Meals
$25–$50
Total
$63–$88
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 82.9 kg one way. Prices: EIA weekly data, 2026-04-06.
Driving Electric?
About $25 in charging · 0 stops · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 71.1 | 0 | $24.87 | $11.37 |
| Efficient EV | 59.2 | 0 | $20.73 | $9.48 |
| EV Truck/SUV | 94.8 | 1 | $33.17 | $15.16 |
Gas CO2
83 kg
EV CO2
28 kg (66% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Afternoon in Myrtle Beach on Sunday
Local time
4:06 PM
EDT
Current temp
65°F
Unavailable
Destination
Afternoon in Spartanburg on Sunday
Local time
4:06 PM
EDT
Current temp
64°F
Unavailable
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
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