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Trip from Myrtle Grove, FL to Cape Coral, FL

Drive Time

10h 59m

Distance

595.7 mi

959 km

Drive Score

8/10

Great drive

Same Day?

2-day trip

Fuel Cost

$100

one way

EV Charging

None

0 DC fast

Best Time to Leave

Save up to 29 min
4 AM
10h 50m ★
6 AM
11h 0m
8 AM
11h 19m
10 AM
11h 7m
12 PM
11h 5m
3 PM
11h 8m
5 PM
11h 18m
8 PM
10h 54m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Best Time Drive vs Fly
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Downtown Cape Coral, FL, FL

Cape Coral, FL

DΛVΞ GΛRCIΛ

Trip Overview

The drive from Myrtle Grove, FL to Cape Coral, FL covers 595.7 miles and takes about 10h 59m behind the wheel. It usually feels better as a 2-day road trip than as one long push.

The route leans on I 10, I 75, Tamiami Trail for much of the mileage, and the overall profile is long-distance drive. The longest uninterrupted segment is about 282.9 miles on I 10. At current regular gas prices, budget about $99.51 one way before food or hotel costs.

Trip Pace

Best split across 2 days

Treat the return leg as its own travel day rather than an afterthought.

Break Rhythm

3 planned breaks

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

297.8 miles from Myrtle Grove, FL

A natural place for your longest stop of the day , about 5h 26m into the drive .

Drive Character

At 595.7 miles and 10h 59m of driving, this is a route where fuel stops, weather, and timing matter more than any single turn. The main roads are I 10 and I 75.

Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 25 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
I 10 is the longest continuous segment at about 282.9 miles.

How Hard Is This Drive?

This is a straightforward highway drive that stays mostly on I 10 and I 75. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes early in the drive.

Route Complexity 8/10

Demanding - plan breaks and stay ahead of the key maneuvers

This is a demanding drive. With 20 significant decision points across 595.7 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: near the start: Complex interchange - multiple decisions in a short stretch; at 9.6 miles: Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 454.4 miles (I 75): Highway fork - watch signs carefully. Lane positioning matters here.

Critical Maneuvers

5 of 20 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

6
0 mi into trip | ~0m in

At end of road, turn right

Complex interchange - multiple decisions in a short stretch

9
9.6 mi into trip | ~17m in

Keep slight right at fork toward I 10 East, FL 291: Tallahassee, Davis Highway

Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one

Use the straight / slight right lanes. Exit 6 Toward I 10 East, FL 291: Tallahassee, Davis Hi...
7
454.4 mi into trip | ~8h 14m in | I 75

Keep slight left at fork onto I 75 toward South I 75: Naples

Highway fork - watch signs carefully. Lane positioning matters here

Use the straight / slight right lanes. Toward South I 75: Naples
6
528.7 mi into trip | ~9h 34m in | I 75

Keep slight left at fork onto I 75

Highway fork - watch signs carefully. Lane positioning matters here

Use the straight / slight right lanes.
7
571.2 mi into trip | ~10h 20m in

Keep slight right at fork toward CR 762 West, to US 41

Highway fork - watch signs carefully. Multiple destination signs - pick the right one

Toward CR 762 West, to US 41

Main Roads

Road Distance Duration
I 10 282.9 mi 5h 3m
I 75 277 mi 4h 56m
Tamiami Trail 10.4 mi 12m
Del Prado Boulevard North 6.5 mi 10m
Del Prado Boulevard South 6.2 mi 12m
West Fairfield Drive 4.6 mi 8m
Reubin O'Donovan Askew Parkway 3.3 mi 3m
Lillian Highway 1 mi 2m
Longest stretch: I 10 — 282.9 mi, about 5h 3m

Turn-by-Turn Driving Directions

Step-by-step road directions between Myrtle Grove, FL and Cape Coral, FL.

1

Start on this road

121 ft · 10 sec · this road
2

At end of road, turn right

52 ft · 8 sec
3

Turn left onto FL 298

1.0 mi · 2 min · Lillian Highway
4

Turn left onto North 57th Avenue

0.4 mi · 1 min · North 57th Avenue
Use the left lane.
5

At end of road, turn right onto FL 727

3.8 mi · 7 min · West Fairfield Drive
6

Keep slight left at fork onto FL 295

0.9 mi · 1 min · West Fairfield Drive
7

Turn right onto FL 291

0.1 mi · 12 sec · North Davis Highway
8

Take the ramp

0.2 mi · 24 sec
Toward I 110 North
9

Merge onto I 110

3.3 mi · 3 min · Reubin O'Donovan Askew Parkway
Use the straight / slight right lanes.
10

Keep slight right at fork

0.3 mi · 28 sec
Exit 6 Toward I 10 East, FL 291: Tallahassee, Davis Highway Use the straight / slight right lanes.
11

Keep slight left at fork

0.7 mi · 1 min
Toward I 10 East: Tallahassee
12

Merge onto I 10

283 mi · 5 hr 3 min · I 10
Use the straight / slight right lanes.
13

Take the exit

0.4 mi · 37 sec
Exit 296A Toward I-75 South: Tampa
14

Merge onto I 75

161 mi · 2 hr 52 min · I 75
Use the straight lane.
15

Keep slight left at fork onto I 75

74 mi · 1 hr 19 min · I 75
Toward South I 75: Naples Use the straight / slight right lanes.
16

Keep slight left at fork onto I 75

42 mi · 45 min · I 75
Use the straight / slight right lanes.
17

Take the exit

0.3 mi · 37 sec
Exit 158 Toward CR 762: North Fort Myers, Cape Coral
18

Keep slight right at fork

0.2 mi · 21 sec
Toward CR 762 West, to US 41
19

Turn straight onto CR 762

0.9 mi · 1 min · Tuckers Grade
20

Turn left onto US 41

10 mi · 12 min · Tamiami Trail
Use the right lane.
21

Turn right onto CR 867A

6.5 mi · 10 min · Del Prado Boulevard North
Use the left lane.
22

Continue on CR 867A

6.2 mi · 12 min · Del Prado Boulevard South
23

Turn right onto Cape Coral Parkway East

0.3 mi · 41 sec · Cape Coral Parkway East
Use the right lane.
24

Turn right

200 ft · 14 sec
25

Arrive at destination

Trip Plan

Morning Departure

Start early — leave by 6-7 AM to arrive at a reasonable hour.

Evening Departure

This is a long drive — plan for a morning departure or consider splitting it into two days.

This drive is better paced as a 2-day trip.
Plan roughly 3 meaningful breaks for fuel, food, and rest.
The halfway point lands around 297.8 miles from Myrtle Grove, FL, or about 5h 26m into the drive.
The longest continuous stretch on this route runs about 282.9 miles.

Consider an overnight stop or starting very early.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 131 miles or 2h 27m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 297.8 miles or 5h 26m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Overnight split

Day 1 wrap after about 297.8 miles or 5h 26m

Stop before fatigue turns the last few hours into a grind. You want day two to start fresh, not just resumed.

Final approach

Final hour starts around 9h 41m

Traffic, exits, and arrival timing usually matter more near Cape Coral, FL than in the middle of the route.

Before You Leave

+

Open the route before leaving Myrtle Grove, FL so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

+

Pick one backup stop option before the midpoint in case traffic changes your pacing.

+

Treat this as a 2-day road trip and book the overnight stop before the busiest arrival window.

Day 1

Settle into the route from Myrtle Grove, FL

Aim for roughly 298 miles and 5.5 hours of wheel time on this day.

Day 2

Finish the approach into Cape Coral, FL

Aim for roughly 298 miles and 5.5 hours of wheel time on this day.

Your first comfortable stop window is around 131 miles from Myrtle Grove, FL.
This route usually feels better as a 2-day drive than as one long push.
Plan about 3 real breaks rather than only quick fuel stops.
The longest stretch is on I 10 for about 282.9 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 297.8 mi from Myrtle Grove, FL · 5h 26m into the drive

First major stop

Coffee and fuel

Tallahassee, FL

197 mi into the route

Best for: Coffee, fuel, and an easy first stretch

This is a natural early stop once the first hours of the drive are behind you.

Popular next leg

Tallahassee, FL to Cape Coral, FL

407.2 mi · 6h 4m

Downtown Apollo Beach, FL, FL

Second major stop

Overnight candidate

Apollo Beach, FL

393 mi into the route

Best for: Hotel check-in, dinner, and a fresh start

This lines up well with a realistic day-end stop if you are breaking the drive into stages.

Find hotels in Apollo Beach, FL

Popular next leg

Apollo Beach, FL to Cape Coral, FL

117.7 mi · 2h 23m

Overnight Options

Night 1

Gainesville, FL

298 mi · about 5.5h in

A practical overnight split lands near Gainesville, FL after about 298 miles or 5.5 hours of driving.

Find hotels

Pacing Suggestions

Dothan, AL

Fuel and coffee

A short stop after about 131 miles helps settle the day before fatigue starts building.

Lake City, FL

Meal break

The midpoint is around 297.8 miles from Myrtle Grove, FL, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before I 10 if your tank is already low. That segment runs about 282.9 miles.

Overnight split

Hotel stop

For a steadier pace, wrap day one after about 298 miles or 5.5 hours on the road.

Arriving in Cape Coral, FL

The final approach into Cape Coral, FL usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Cape Coral, FL.

On a multi-day trip, keep the last day a little lighter so you reach Cape Coral, FL with some flexibility left in the schedule.

After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

National Parks Near This Route

Worth a detour if your schedule allows.

Gulf Islands National Seashore

Gulf Islands National Seashore

National Seashore

Millions of visitors are drawn to the Gulf of America for Gulf Islands National Seashore's emerald coast waters, magnificent white beaches, fertile marshes and historical landscapes. Come explore with...

8 mi from route ~21 min detour $25
Park Closure: Fort Pickens Campground Restroom A Loop Closure
Caution: Road workers on Park Road in Davis Bayou
View on nps.gov
De Soto National Memorial

De Soto National Memorial

National Memorial

In May 1539, Conquistador Hernando de Soto’s army of soldiers, hired mercenaries, craftsmen, and clergy made landfall in Tampa Bay. They were met with fierce resistance of indigenous people protecting...

14 mi from route ~35 min detour Free near mile 513.5
View on nps.gov

Park data from the National Park Service API. Alerts update every 2 hours.

Fuel & Cost

Regular Gas

$99.51 one way

$199.02 round trip

$4.24/gal 25.4 MPG avg 208 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.60 $107.79 $215.58
premium $4.90 $114.82 $229.65
diesel $5.64 $132.34 $264.69

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$100

Hotel (1n)

$80–$140

Meals

$50–$100

Total

$230–$340

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 208.4 kg one way. Prices: EIA weekly data, 2026-04-06.

Driving Electric?

About $63 in charging · 2 stops · 66% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 178.7 2 $62.55 $28.59
Efficient EV 148.9 1 $52.12 $23.83
EV Truck/SUV 238.3 2 $83.40 $38.12

Gas CO2

208 kg

EV CO2

70 kg (66% less)

Plan for 2 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast data refreshed 3 days ago

Origin

Myrtle Grove, FL

Morning in Myrtle Grove on Monday

Local time

11:07 AM

CDT

Current temp

66°F

Unavailable

Live forecast

Destination

Cape Coral, FL

Afternoon in Cape Coral on Monday

Local time

12:07 PM

EDT

Current temp

67°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

For long drives, weather on day two can matter just as much as conditions at departure, so check the whole travel window rather than only the first day.

Time zone

1 hour later

The destination clock does not match departure time, so double-check hotel check-in windows and late arrival plans.

Temperature spread

1 degrees warmer at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

10h 59m on the road

This is long enough that the arrival forecast matters almost as much as departure conditions. Recheck both ends before you roll.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Myrtle Grove, FL to Cape Coral, FL covers 595.7 miles and takes about 10h 59m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are I 10, I 75, Tamiami Trail. Expect a mix of highway and local road driving.
Consider an overnight stop or starting very early.
Yes. This route is usually more comfortable as a 2-day drive. A sensible stopping point is after roughly 298 miles on day one.
The midpoint is about 297.8 miles from Myrtle Grove, FL. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $99.51 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.
Plan about 3 meaningful breaks for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 20 significant decision points across 595.7 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: near the start: Complex interchange - multiple decisions in a short stretch; at 9.6 miles: Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 454.4 miles (I 75): Highway fork - watch signs carefully. Lane positioning matters here.
The route from Myrtle Grove, FL to Cape Coral, FL does not surface many named destination signs beyond the main corridor.

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