Origin
North La Crosse, WI
Afternoon in North La Crosse on Sunday
Local time
3:06 PM
CDT
Current temp
39°F
Unavailable
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Create accountDrive Time
4h 13m
Distance
197.7 mi
318 km
Drive Score
7/10
Good drive
Same Day?
Yes, doable
Fuel Cost
$30
one way
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
North La Crosse, WI
Tom Fisk
De Pere, WI
Israel Torres
If you are planning to cross Wisconsin from North La Crosse to De Pere, expect a straightforward journey covering 197.7 miles. You should budget about 4 hours and 13 minutes of drive time, making this a very manageable single-day trip. With an estimated fuel cost of $30, it is an affordable route for a weekend getaway or a necessary commute. The path utilizes a combination of I-90, I-41, and State Highway 82 to get you across the state efficiently. Since the entire trip takes place within the Midwest, you can anticipate consistent road conditions throughout. It is best treated as a one-day excursion, allowing you to reach your destination without the need for an overnight stop.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
98.8 miles from North La Crosse, WI
A natural place for your longest stop of the day , about 2h into the drive .
This highway-focused drive is built for efficiency, with 94% of your journey spent on high-speed roads. You will settle into a steady rhythm quickly, especially during the longest uninterrupted stretch of 51.9 miles on I-90. While the interstate segments facilitate rapid progress, the inclusion of State Highway 82 provides a transition between these major arteries. Behind the wheel, you should expect a consistent, predictable driving experience that favors speed over winding secondary roads. The route balances heavy interstate travel with necessary highway connections, ensuring you stay on track as you navigate from the western side of the state toward the De Pere area.
This is a straightforward highway drive that stays mostly on I 90 and I 41. You will hit about 15 points where you need to pay attention to lane position or signs. The trickiest moment comes around 67.1 miles in.
Moderate - straightforward overall, but long enough or busy enough to require pacing
This drive requires moderate attention. Across 197.7 miles you will encounter 15 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: at 67.1 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 67.6 miles (State Highway 82): Navigation decision point; at 149.1 miles: Complex interchange - multiple decisions in a short stretch.
These are the spots where you need to pay the most attention. Preview them before you drive.
Take the exit toward WI 82: Mauston, Oxford
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
At end of road, turn left onto State Highway 82
Navigation decision point
Turn left toward I-41_North: Appleton
Complex interchange - multiple decisions in a short stretch
Merge onto I 41; US 41 toward Appleton
Merge point - match speed before joining. Lane positioning matters here
Take the exit toward CTH G
Exit ramp - move to the correct lane early
Between North La Crosse, WI and De Pere, WI, road signs point toward Oxford and Appleton.
Oxford
Appleton
| Road | Distance | Duration |
|---|---|---|
| I 90 | 51.9 mi | 55m |
| I 41 | 46.3 mi | 49m |
| State Highway 82 | 28.3 mi | 42m |
| State Highway 23 | 16 mi | 23m |
| State Highway 44 | 14.8 mi | 21m |
| US 53 | 14 mi | 15m |
| State Highway 23 & 73 | 9.5 mi | 13m |
| State Highway 23 & 49 | 3.4 mi | 4m |
Step-by-step road directions between North La Crosse, WI and De Pere, WI.
Start on US 53; CTH B
Take the exit onto US 53
Continue on I 90
Take the exit
Turn left onto State Highway 82
Continue on State Highway 82
At end of road, turn left onto State Highway 82
Continue on WI 82
Continue on WI 82
Continue on WI 82
Continue on State Highway 23
Continue on WI 23
Continue on WI 23; CTH C
Continue on WI 22; WI 23; CTH C
Continue on WI 23
Continue on WI 23
Turn right onto WI 73; CTH J
Turn right onto WI 23; WI 73; CTH D
Continue on WI 23; WI 73
Continue on WI 23; WI 49
Continue on WI 23; WI 49
Turn left onto CTH FF
Turn straight onto West Oshkosh Street
Keep slight left at fork onto East Oshkosh Street
Continue on WI 44
Continue on WI 44; WI 91
Continue on WI 44; WI 91
Turn left
Merge onto I 41; US 41
Take the exit
Keep slight right at fork
Turn right onto West Main Avenue
Enter roundabout onto West Main Avenue
Continue on West Main Avenue
Continue on WI 32
Turn left onto WI 32
Keep slight right at fork onto WI 32
Enter roundabout onto WI 57
Continue on WI 57
Arrive at destination
For a smooth experience, plan for at least one dedicated stop to break up the four-hour duration. Because this route relies heavily on major corridors, you should check traffic reports for I-90 and I-41 before departing, as these roads can experience congestion near urban centers. Keeping your fuel budget around $30 is realistic, but it is wise to fill up before hitting the longer stretches to avoid inflated prices at remote stations. Since the drive is short enough to complete in a single day, you have the flexibility to leave in the morning or afternoon based on your preference. Prioritize a steady pace during the 51.9-mile stretch on I-90 to maintain your arrival schedule.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 33m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 98.8 miles or 2h in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 31m
Traffic, exits, and arrival timing usually matter more near De Pere, WI than in the middle of the route.
Open the route before leaving North La Crosse, WI so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from North La Crosse, WI
This is one driving day of about 197.7 miles and 4h 13m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 98.8 mi from North La Crosse, WI · 2h into the drive
Mid-route town
Meal stop
99 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 80 miles helps settle the day before fatigue starts building.
The midpoint is around 98.8 miles from North La Crosse, WI, which is a good place for a longer meal and fuel stop.
The final approach into De Pere, WI usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around De Pere, WI.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$30.03 one way
$60.06 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.25 | $33.10 | $66.21 |
| premium | $4.80 | $37.32 | $74.64 |
| diesel | $5.64 | $43.92 | $87.84 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$30
Meals
$25–$50
Total
$55–$80
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 69.2 kg one way. Prices: EIA weekly data, 2026-04-06.
Driving Electric?
About $21 in charging · 0 stops · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 59.3 | 0 | $20.76 | $9.49 |
| Efficient EV | 49.4 | 0 | $17.30 | $7.91 |
| EV Truck/SUV | 79.1 | 0 | $27.68 | $12.65 |
Gas CO2
69 kg
EV CO2
23 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Afternoon in North La Crosse on Sunday
Local time
3:06 PM
CDT
Current temp
39°F
Unavailable
Destination
Afternoon in De Pere on Sunday
Local time
3:06 PM
CDT
Current temp
45°F
Unavailable
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
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