Trip from North Myrtle Beach, SC to Spartanburg, SC

Drive Time

4h 5m

Distance

254.5 mi

Route Type

Turn-heavy local drive

Long day trip

Trip Overview

The drive from North Myrtle Beach, SC to Spartanburg, SC covers 254.5 miles and takes about 4h 5m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on Highway 17 South, Robert Edge Parkway, US 501 for much of the mileage, and the overall profile is turn-heavy local drive. At current regular gas prices, budget about $39.69 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

127.2 miles from North Myrtle Beach, SC

A natural place for your longest stop of the day@if(!empty($enrichment->halfway_point['drive_time'])), about 0m into the drive@endif.

Drive Character

Expect a 4h 5m drive with frequent turns across 254.5 miles of local and secondary roads.

This route has more turning and local-road decision points than a simple highway run.

There are about 25 navigation steps in the underlying route data, so the final approach matters more than the middle miles.

Highway 17 South is one of the defining roads on this drive.

Main Roads

Road	Distance	Duration
Highway 17 South	0 mi	0m
Robert Edge Parkway	0 mi	0m
US 501	0 mi	0m
Carolina Bays Parkway	0 mi	0m
SC 22	0 mi	0m
SC 22 West	0 mi	0m
Veterans Highway	0 mi	0m
US 501 North	0 mi	0m

Longest stretch: Highway 17 South — 0 mi, about 0m

Step-by-Step Directions

1

Start on 6th Avenue South

2

Turn right onto US Highway 17 South

3

Turn left onto Robert Edge Parkway

4

Turn left onto SC 31 South: US 501, Myrtle Beach

5

Merge slight left onto Carolina Bays Parkway

6

Take the exit slight right toward SC 22: Myrtle Beach, Conway

7

Keep slight right to continue on SC 22 West: Conway

8

Merge slight left onto Veterans Highway

9

Keep slight right to continue on US 501 North: Aynor, Marion

10

Merge slight left

11

Turn straight

12

Continue straight

13

Continue straight

14

Turn slight right onto East Cheves Street

15

Turn right onto Warley Street

16

Turn left onto West Evans Street

17

Turn right onto West David H McLeod Boulevard

18

Continue on J Strom Thurmond Freeway

19

Take the exit slight right toward I 26 West

20

Merge slight left

21

Keep slight right to continue on Spartanburg

22

Take the exit slight right toward US 221: Spartanburg-South, Moore

23

Turn straight onto Highway 221

24

Continue on South Church Street

25

Arrive at your destination

When to Leave

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.

Plan roughly 1 meaningful break for fuel, food, and rest.

The halfway point lands around 127.2 miles from North Myrtle Beach, SC, or about 0m into the drive.

This is a comfortable same-day trip.

Drive Plan

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 80 miles or 0m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 127.2 miles or 0m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 0m

Traffic, exits, and arrival timing usually matter more near Spartanburg, SC than in the middle of the route.

Before You Leave

+

Open the route before leaving North Myrtle Beach, SC so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Trip Strategy

Day 1

Settle into the route from North Myrtle Beach, SC

This is one driving day of about 254.5 miles and 4h 5m.

Your first comfortable stop window is around 80 miles from North Myrtle Beach, SC.

This route can stay practical as a one-day drive if traffic stays reasonable.

Plan about 1 real break rather than only quick fuel stops.

Best Stop Towns on This Route

These towns line up with the pace of this drive and give you clearer places to stop with a purpose.

Late stop town

Meal stop

Charlotte, NC

127 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Travel Advice

Arrival Notes

The final approach into Spartanburg, SC usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Spartanburg, SC.

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Stops Along the Way

Halfway Point

Midpoint

About 127.2 mi from North Myrtle Beach, SC

Fayetteville, NC

Fuel and coffee

A short stop after about 80 miles helps settle the day before fatigue starts building.

Charlotte, NC

Meal break

The midpoint is around 127.2 miles from North Myrtle Beach, SC, which is a good place for a longer meal and fuel stop.

These stop ideas are pacing suggestions for the drive, so the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Fuel Type	$/gal	One Way	Round Trip
regular	$3.96	$39.69	$79.38
midgrade	$4.43	$44.38	$88.75
premium	$4.78	$47.87	$95.75
diesel	$5.62	$56.35	$112.70

Based on 25.4 MPG average. Estimated CO2 emission: 89 kg one way.

Frequently Asked Questions

The drive from North Myrtle Beach, SC to Spartanburg, SC covers 254.5 miles and takes about 4h 5m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.

The main roads are Highway 17 South, Robert Edge Parkway, US 501. Expect a mix of highway and local road driving.

This is a comfortable same-day trip.

The midpoint is about 127.2 miles from North Myrtle Beach, SC. Look for rest areas, gas stations, or food options near the halfway mark.

At current regular gas prices, expect to spend about $39.69 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.

An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.

Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.