Trip from O'Fallon, MO to Cabool, MO

Drive Time

3h 27m

Distance

166.3 mi

268 km

Drive Score

9/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$25

one way

EV Charging

Loading...

station data

Best Time to Leave

Save up to 37 min
4 AM
3h 15m ★
6 AM
3h 28m
8 AM
3h 52m
10 AM
3h 36m
12 PM
3h 34m
3 PM
3h 37m
5 PM
3h 51m
8 PM
3h 20m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown O'Fallon, MO, MO

O'Fallon, MO

Valeria Boltneva

Downtown Cabool, MO, MO

Cabool, MO

Collab Media

Trip Overview

Traveling from O'Fallon to Cabool covers 166.3 miles and takes approximately 3 hours and 27 minutes. Because this journey fits comfortably into a single day, you won't need to worry about booking an overnight stay. You can expect to spend about $25 on fuel, making this an affordable trip across the Missouri Midwest. The route relies on a mix of I-44, North Bishop Avenue, and MO-100 to get you to your destination. Whether you are heading out for business or a change of scenery, the straightforward nature of this drive makes it a manageable trek for any driver.

Trip Pace

Same-day drive is realistic

A same-day return is realistic if you keep stops short.

Break Rhythm

1 planned break

A short stop every 2 to 3 hours is enough for this drive.

Midpoint

83.1 miles from O'Fallon, MO

A natural place for your longest stop of the day , about 1h 46m into the drive .

Drive Character

Expect a mixed driving experience as you transition from major interstates to local roads. With 52% of the journey spent on highways, you will encounter both fast-paced travel and slower, more deliberate stretches. Your longest uninterrupted segment occurs on I-44, spanning 67.3 miles of the total distance. As you move away from the interstate, the character of the road shifts, requiring you to adjust your pace when navigating North Bishop Avenue and MO-100. It is a varied route that keeps you alert by balancing high-speed transit with more technical, localized segments.

Expect a mix of faster highway mileage and slower local approaches near the beginning or end.
There are about 29 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
I 44 is the longest continuous segment at about 67.3 miles.

Elevation Profile

Gently rolling terrain

1,290 ft 465 ft

Total Climb

1,294 ft

Total Descent

553 ft

Highest Point

1,290 ft

~138.6 mi in

Elevation Range

825 ft

How Hard Is This Drive?

This route mixes highway mileage with some local-road sections near the start or finish. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 7 miles in.

Route Complexity 7/10

Demanding - plan breaks and stay ahead of the key maneuvers

This is a demanding drive. With 19 significant decision points across 166.3 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: at 7 miles: Lane positioning matters here. Multiple destination signs - pick the right one; at 7.3 miles (I 64; US 40; US 61 / Avenue of the Saints): Merge point - match speed before joining. Lane positioning matters here; at 11 miles: Exit ramp - move to the correct lane early. Lane positioning matters here.

Critical Maneuvers

5 of 19 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

6
7 mi into trip | ~12m in

Take the ramp toward I 64 East, US 40 East, US 61 South

Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Toward I 64 East, US 40 East, US 61 South
5
7.3 mi into trip | ~13m in | I 64; US 40; US 61 / Avenue of the Saints

Merge onto I 64; US 40; US 61 / Avenue of the Saints

Merge point - match speed before joining. Lane positioning matters here

Use the none lane.
7
11 mi into trip | ~17m in

Take the exit toward Chesterfield Airport Road

Exit ramp - move to the correct lane early. Lane positioning matters here

Use the slight right lane. Exit 14 Toward Chesterfield Airport Road
5
11.6 mi into trip | ~19m in | Olive Street Road

Turn right onto Olive Street Road

Lane positioning matters here

Use the none lane.
5
19.7 mi into trip | ~33m in

Enter roundabout toward MO 100 West: Gray Summit

Roundabout - know your exit number before entering

Toward MO 100 West: Gray Summit

Towns Along This Route

On the drive from O'Fallon, MO to Cabool, MO, road signs begin pointing toward Mo E: Rolla along the way.

Mo E: Rolla

100.8 mi in | ~2h 5m

Main Roads

Road Distance Duration
I 44 67.3 mi 1h 12m
North Bishop Avenue 64.3 mi 1h 20m
MO 100 13.3 mi 18m
MO K 6.5 mi 11m
MO 109 4.7 mi 7m
Avenue of the Saints 3.7 mi 4m
North Eatherton Road 2.4 mi 4m
Olive Street Road 0.9 mi 1m
Longest stretch: I 44 — 67.3 mi, about 1h 12m

Turn-by-Turn Driving Directions

Step-by-step road directions between O'Fallon, MO and Cabool, MO.

1

Start on this road

25 ft · 7 sec · this road
2

Turn left onto South Main Street

0.5 mi · 1 min · South Main Street
3

Continue on MO K

3.1 mi · 5 min · MO K
Use the none lane.
4

Continue on MO K

3.4 mi · 5 min · MO K
Use the none lane.
5

Take the ramp

0.3 mi · 21 sec
Toward I 64 East, US 40 East, US 61 South Use the slight right lane.
6

Merge onto I 64; US 40; US 61

3.7 mi · 4 min · Avenue of the Saints
Use the none lane.
7

Take the exit

0.5 mi · 57 sec
Exit 14 Toward Chesterfield Airport Road Use the slight right lane.
8

Continue on Chesterfield Airport Road

361 ft · 6 sec · Chesterfield Airport Road
9

Turn right

211 ft · 5 sec
Toward Olive Street Road
10

Turn right onto Olive Street Road

0.9 mi · 1 min · Olive Street Road
Use the none lane.
11

Continue on North Eatherton Road

2.4 mi · 4 min · North Eatherton Road
12

Enter roundabout onto MO 109

70 ft · 1 sec · MO 109
13

Continue on MO 109

4.3 mi · 6 min · MO 109
14

Enter roundabout onto MO 109

94 ft · 2 sec · MO 109
15

Continue on MO 109

0.4 mi · 44 sec · MO 109
16

Enter roundabout

76 ft · 1 sec
Toward MO 100 West: Gray Summit
17

Continue

0.2 mi · 32 sec
Toward MO 100 West: Gray Summit
18

Merge onto MO 100

13 mi · 18 min · MO 100
19

Take the exit

0.2 mi · 14 sec
Toward I 44 West, US 50 West: St. Clair
20

Merge onto I 44; US 50

67 mi · 1 hr 12 min · I 44; US 50
Use the straight lane.
21

Take the exit

0.2 mi · 19 sec
Exit 185 Toward MO E: Rolla
22

Enter roundabout onto MO E

294 ft · 5 sec · Tim Bradley Way
23

Continue on MO E

0.4 mi · 48 sec · Tim Bradley Way
Use the left / none lanes.
24

Turn slight right onto I 44 Business; US Historic 66; US 63

30 ft · 0 sec · North Bishop Avenue
25

Keep slight right at fork onto I 44 Business; US Historic 66; US 63

145 ft · 2 sec · North Bishop Avenue
26

Continue on I 44 Business; US Historic 66; US 63

64 mi · 1 hr 20 min · North Bishop Avenue
Use the left / straight lanes.
27

Turn right onto US 60 Business

0.5 mi · 59 sec · US 60 Business
Use the right lane.
28

Turn right

120 ft · 8 sec
29

Arrive at destination

Trip Plan

Planning for just one stop is the best way to handle this 166.3-mile trip efficiently. Since the drive is under four hours, you have plenty of flexibility to depart when it suits your schedule, though leaving mid-morning can help you avoid peak traffic on the highway portions. Keep an eye on your fuel levels before leaving the more populated areas, as the transition to local roads may limit your immediate options. Use that single planned stop to stretch your legs and refuel, as the longest 67.3-mile stretch on I-44 can be fatiguing if you don't take a break beforehand. Staying mindful of your transition from the interstate to secondary roads will ensure a smooth arrival in Cabool.

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 83.1 miles from O'Fallon, MO, or about 1h 46m into the drive.
The longest continuous stretch on this route runs about 67.3 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 80 miles or 1h 42m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 83.1 miles or 1h 46m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 2h 49m

Traffic, exits, and arrival timing usually matter more near Cabool, MO than in the middle of the route.

Before You Leave

+

Open the route before leaving O'Fallon, MO so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from O'Fallon, MO

This is one driving day of about 166.3 miles and 3h 27m.

Your first comfortable stop window is around 80 miles from O'Fallon, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 44 for about 67.3 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 83.1 mi from O'Fallon, MO · 1h 46m into the drive

Downtown Cahokia, IL, IL

Mid-route town

Meal stop

Cahokia, IL

83 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Cahokia, IL

Fuel and coffee

A short stop after about 80 miles helps settle the day before fatigue starts building.

Cahokia, IL

Meal break

The midpoint is around 83.1 miles from O'Fallon, MO, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before I 44 if your tank is already low. That segment runs about 67.3 miles.

Arriving in Cabool, MO

The final approach into Cabool, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Cabool, MO.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$25.26 one way

$50.52 round trip

$3.86/gal 25.4 MPG avg 58 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.25 $27.85 $55.69
premium $4.80 $31.39 $62.79
diesel $5.64 $36.95 $73.89

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$25

Meals

$25–$50

Total

$50–$75

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 58.2 kg one way. Prices: EIA weekly data, 2026-04-06.

Driving Electric?

About $17 in charging · 0 stops · 67% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 49.9 0 $17.46 $7.98
Efficient EV 41.6 0 $14.55 $6.65
EV Truck/SUV 66.5 0 $23.28 $10.64

Gas CO2

58 kg

EV CO2

19 kg (67% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast data refreshed 3 days ago

Origin

O'Fallon, MO

Afternoon in O'Fallon on Sunday

Local time

3:51 PM

CDT

Current temp

53°F

Unavailable

Live forecast

Destination

Cabool, MO

Afternoon in Cabool on Sunday

Local time

3:51 PM

CDT

Current temp

42°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

11 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

3h 27m on the road

Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from O'Fallon, MO to Cabool, MO covers 166.3 miles and takes about 3h 27m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are I 44, North Bishop Avenue, MO 100. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 83.1 miles from O'Fallon, MO. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $25.26 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. A short stop every 2 to 3 hours is enough for this drive.
This is a demanding drive. With 19 significant decision points across 166.3 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 7 miles: Lane positioning matters here. Multiple destination signs - pick the right one; at 7.3 miles (I 64; US 40; US 61 / Avenue of the Saints): Merge point - match speed before joining. Lane positioning matters here; at 11 miles: Exit ramp - move to the correct lane early. Lane positioning matters here.
On the drive from O'Fallon, MO to Cabool, MO, road signs begin pointing toward Mo E: Rolla along the way.
Gently rolling terrain. The route ranges from 465 ft to 1,290 ft elevation with about 1,294 ft of total climbing.

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Return Trip

Cabool, MO to O'Fallon, MO

Plan the drive back the other way.

165.9 mi 3h 27m

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