Origin
O'Fallon, MO
Afternoon in O'Fallon on Sunday
Local time
3:51 PM
CDT
Current temp
53°F
Unavailable
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Create accountDrive Time
3h 27m
Distance
166.3 mi
268 km
Drive Score
9/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$25
one way
EV Charging
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station data
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
O'Fallon, MO
Valeria Boltneva
Cabool, MO
Collab Media
Traveling from O'Fallon to Cabool covers 166.3 miles and takes approximately 3 hours and 27 minutes. Because this journey fits comfortably into a single day, you won't need to worry about booking an overnight stay. You can expect to spend about $25 on fuel, making this an affordable trip across the Missouri Midwest. The route relies on a mix of I-44, North Bishop Avenue, and MO-100 to get you to your destination. Whether you are heading out for business or a change of scenery, the straightforward nature of this drive makes it a manageable trek for any driver.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
83.1 miles from O'Fallon, MO
A natural place for your longest stop of the day , about 1h 46m into the drive .
Expect a mixed driving experience as you transition from major interstates to local roads. With 52% of the journey spent on highways, you will encounter both fast-paced travel and slower, more deliberate stretches. Your longest uninterrupted segment occurs on I-44, spanning 67.3 miles of the total distance. As you move away from the interstate, the character of the road shifts, requiring you to adjust your pace when navigating North Bishop Avenue and MO-100. It is a varied route that keeps you alert by balancing high-speed transit with more technical, localized segments.
Gently rolling terrain
Total Climb
1,294 ft
Total Descent
553 ft
Highest Point
1,290 ft
~138.6 mi in
Elevation Range
825 ft
This route mixes highway mileage with some local-road sections near the start or finish. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 7 miles in.
Demanding - plan breaks and stay ahead of the key maneuvers
This is a demanding drive. With 19 significant decision points across 166.3 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 7 miles: Lane positioning matters here. Multiple destination signs - pick the right one; at 7.3 miles (I 64; US 40; US 61 / Avenue of the Saints): Merge point - match speed before joining. Lane positioning matters here; at 11 miles: Exit ramp - move to the correct lane early. Lane positioning matters here.
These are the spots where you need to pay the most attention. Preview them before you drive.
Take the ramp toward I 64 East, US 40 East, US 61 South
Lane positioning matters here. Multiple destination signs - pick the right one
Merge onto I 64; US 40; US 61 / Avenue of the Saints
Merge point - match speed before joining. Lane positioning matters here
Take the exit toward Chesterfield Airport Road
Exit ramp - move to the correct lane early. Lane positioning matters here
Turn right onto Olive Street Road
Lane positioning matters here
Enter roundabout toward MO 100 West: Gray Summit
Roundabout - know your exit number before entering
On the drive from O'Fallon, MO to Cabool, MO, road signs begin pointing toward Mo E: Rolla along the way.
Mo E: Rolla
| Road | Distance | Duration |
|---|---|---|
| I 44 | 67.3 mi | 1h 12m |
| North Bishop Avenue | 64.3 mi | 1h 20m |
| MO 100 | 13.3 mi | 18m |
| MO K | 6.5 mi | 11m |
| MO 109 | 4.7 mi | 7m |
| Avenue of the Saints | 3.7 mi | 4m |
| North Eatherton Road | 2.4 mi | 4m |
| Olive Street Road | 0.9 mi | 1m |
Step-by-step road directions between O'Fallon, MO and Cabool, MO.
Start on this road
Turn left onto South Main Street
Continue on MO K
Continue on MO K
Take the ramp
Merge onto I 64; US 40; US 61
Take the exit
Continue on Chesterfield Airport Road
Turn right
Turn right onto Olive Street Road
Continue on North Eatherton Road
Enter roundabout onto MO 109
Continue on MO 109
Enter roundabout onto MO 109
Continue on MO 109
Enter roundabout
Continue
Merge onto MO 100
Take the exit
Merge onto I 44; US 50
Take the exit
Enter roundabout onto MO E
Continue on MO E
Turn slight right onto I 44 Business; US Historic 66; US 63
Keep slight right at fork onto I 44 Business; US Historic 66; US 63
Continue on I 44 Business; US Historic 66; US 63
Turn right onto US 60 Business
Turn right
Arrive at destination
Planning for just one stop is the best way to handle this 166.3-mile trip efficiently. Since the drive is under four hours, you have plenty of flexibility to depart when it suits your schedule, though leaving mid-morning can help you avoid peak traffic on the highway portions. Keep an eye on your fuel levels before leaving the more populated areas, as the transition to local roads may limit your immediate options. Use that single planned stop to stretch your legs and refuel, as the longest 67.3-mile stretch on I-44 can be fatiguing if you don't take a break beforehand. Staying mindful of your transition from the interstate to secondary roads will ensure a smooth arrival in Cabool.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 42m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 83.1 miles or 1h 46m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 49m
Traffic, exits, and arrival timing usually matter more near Cabool, MO than in the middle of the route.
Open the route before leaving O'Fallon, MO so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from O'Fallon, MO
This is one driving day of about 166.3 miles and 3h 27m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 83.1 mi from O'Fallon, MO · 1h 46m into the drive
Mid-route town
Meal stop
83 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 80 miles helps settle the day before fatigue starts building.
The midpoint is around 83.1 miles from O'Fallon, MO, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before I 44 if your tank is already low. That segment runs about 67.3 miles.
The final approach into Cabool, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Cabool, MO.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$25.26 one way
$50.52 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.25 | $27.85 | $55.69 |
| premium | $4.80 | $31.39 | $62.79 |
| diesel | $5.64 | $36.95 | $73.89 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$25
Meals
$25–$50
Total
$50–$75
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 58.2 kg one way. Prices: EIA weekly data, 2026-04-06.
Driving Electric?
About $17 in charging · 0 stops · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 49.9 | 0 | $17.46 | $7.98 |
| Efficient EV | 41.6 | 0 | $14.55 | $6.65 |
| EV Truck/SUV | 66.5 | 0 | $23.28 | $10.64 |
Gas CO2
58 kg
EV CO2
19 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Afternoon in O'Fallon on Sunday
Local time
3:51 PM
CDT
Current temp
53°F
Unavailable
Destination
Afternoon in Cabool on Sunday
Local time
3:51 PM
CDT
Current temp
42°F
Unavailable
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
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