The drive from Orlando, FL to San Antonio, FL covers 68.7 miles and takes about 1h 39m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on FL 50, Treiman Boulevard, East-West Expressway for much of the mileage,
and the overall profile is highway-focused drive.
The longest uninterrupted segment is about 28.8 miles on FL 50.
At current regular gas prices, budget about $10.94 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Midpoint
34.4 miles from Orlando, FL
A natural place for your longest stop of the day
, about 47m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 1h 39m. Total distance: 68.7 miles.
Family Friendly
Moderate complexity with 0 natural rest stops along the way.
Solo Traveler
1h 39m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (64%). Some complex stretches to watch for.
Drive Character
This is a 1h 39m highway drive covering 68.7 miles, with most of the trip on FL 50 and Treiman Boulevard. The longest continuous stretch is about 28.8 miles on FL 50.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 24 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
FL 50 is the longest continuous segment at about 28.8 miles.
How Hard Is This Drive?
This is a straightforward highway drive that stays mostly on FL 50 and Treiman Boulevard. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 9.5 miles in.
Driving Effort10/10
Demanding - stay alert through the decision-heavy sections
Balances navigation complexity with total wheel time.
This drive requires moderate attention. Across 68.7 miles you will encounter 12 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: at 9.5 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 16.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 16.5 miles: Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
Critical Maneuvers
5 of 12 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
6
9.5 mi into trip|~12m in
Keep slight right at fork toward Florida's Turnpike North, Ocala
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward Florida's Turnpike North, Ocala
8
16.3 mi into trip|~19m in
Take the exit toward FL 50: Winter Garden, Clermont
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 272
Toward FL 50: Winter Garden, Clermont
9
16.5 mi into trip|~20m in
Keep slight right at fork toward FL 50 East: Clermont, Winter Garden
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Toward FL 50 East: Clermont, Winter Garden
7
16.6 mi into trip|~20m in
Keep slight left at fork toward FL 50 West: Clermont
Highway fork - watch signs carefully. Lane positioning matters here
Use the straight / slight right lanes.
Toward FL 50 West: Clermont
6
68.5 mi into trip|~1h 38m in|Park Street
At end of road, turn right onto Park Street
Complex interchange - multiple decisions in a short stretch
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Orlando, FL and San Antonio, FL, road signs point toward Florida's Turnpike North, Ocala, Clermont and Winter Garden.
Florida's Turnpike North
9.5 mi in|~12m
Ocala
9.5 mi in|~12m
Clermont
16.3 mi in|~19m
Winter Garden
16.5 mi in|~20m
Main Roads
Road
Distance
Duration
FL 50
28.8 mi
42m
Treiman Boulevard
9.3 mi
13m
East-West Expressway
8.2 mi
9m
West Colonial Drive
6.7 mi
10m
Florida's Turnpike
6.2 mi
6m
Old State Road 52
4.4 mi
6m
21st Street
1.5 mi
2m
Spessard L. Holland East-West Expressway
0.8 mi
<1m
Longest stretch:
FL 50
— 28.8 mi, about 42m
Turn-by-Turn Driving Directions
Step-by-step road directions between Orlando, FL and San Antonio, FL.
1
Start on this road
113 ft·4 sec·this road
2
Turn right onto FL 527
0.1 mi·26 sec·South Orange Avenue
3
Turn straight
238 ft·10 sec
4
Turn slight right onto Lucerne Circle West
285 ft·12 sec·Lucerne Circle West
5
Take the ramp
0.3 mi·32 sec
Toward FL 408 Toll West
6
Merge onto FL 408 Toll
8.2 mi·9 min·East-West Expressway
Use the straight / slight right lanes.
7
Continue on FL 408 Toll
0.8 mi·53 sec·Spessard L. Holland East-West Expressway
Use the straight / slight right lanes.
8
Keep slight right at fork
0.6 mi·1 min
Toward Florida's Turnpike North, Ocala
9
Merge onto Florida's Turnpike
6.2 mi·6 min·Florida's Turnpike
Use the straight / slight right lanes.
10
Take the exit
0.2 mi·30 sec
Exit 272Toward FL 50: Winter Garden, ClermontUse the slight right lane.
11
Keep slight right at fork
398 ft·9 sec
Toward FL 50 East: Clermont, Winter GardenUse the straight / slight right lanes.
12
Keep slight left at fork
0.3 mi·47 sec
Toward FL 50 West: ClermontUse the straight / slight right lanes.
13
Merge onto FL 50
6.7 mi·10 min·West Colonial Drive
Use the left lane.
14
Continue on FL 50
29 mi·42 min·FL 50
15
Turn left onto US 301
9.3 mi·13 min·Treiman Boulevard
16
Turn slight right
153 ft·5 sec
17
Turn slight right onto Lock Street
0.7 mi·1 min·Lock Street
18
Turn left onto CR 41
1.5 mi·2 min·21st Street
19
Continue on CR 52
4.4 mi·6 min·Old State Road 52
Use the straight lane.
20
Enter roundabout onto College Avenue
111 ft·3 sec·College Avenue
21
Continue on College Avenue
380 ft·12 sec·College Avenue
22
At end of road, turn right onto Park Street
193 ft·5 sec·Park Street
23
Continue on Pennsylvania Avenue
0.2 mi·26 sec·Pennsylvania Avenue
24
Arrive at destination
Pennsylvania Avenue
Trip Plan
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 34.4 miles from Orlando, FL, or about 47m into the drive.
The longest continuous stretch on this route runs about 28.8 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 15 miles or 18m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 34.4 miles or 47m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 1h 22m
Traffic, exits, and arrival timing usually matter more near San Antonio, FL than in the middle of the route.
Before You Leave
+
Open the route before leaving Orlando, FL so your first major turns are already loaded.
Day 1
Settle into the route from Orlando, FL
This is one driving day of about 68.7 miles and 1h 39m.
Your first comfortable stop window is around 15 miles from Orlando, FL.
This route can stay practical as a one-day drive if traffic stays reasonable.
The longest stretch is on FL 50 for about 28.8 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 34.4 mi from Orlando, FL
· 47m into the drive
Station data from NREL Alternative Fuel Stations database.
Driving Electric?
About $7 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
20.6
0
$7.21
$3.30
Efficient EV
17.2
0
$6.01
$2.75
EV Truck/SUV
27.5
0
$9.62
$4.40
Gas CO2
24 kg
EV CO2
8 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 18, 2026
Origin
Orlando, FL
Morning
in Orlando on Saturday
Local time
11:59 AM
EDT
Current temp
67°F
Patchy Fog
SSW 5 mph1% chanceLive forecast
Red Flag Warning
Red Flag Warning issued April 18 at 2:27AM EDT until April 18 at 8:00PM EDT by NWS Tallahassee FL
Fire Weather Watch
Fire Weather Watch issued April 18 at 2:27AM EDT until April 20 at 8:00PM EDT by NWS Tallahassee FL
Destination
San Antonio, FL
Morning
in San Antonio on Saturday
Local time
11:59 AM
EDT
Current temp
60°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
7 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
1h 39m on the road
The weather snapshot is not static. If you are leaving later, give both cities one more quick forecast check before departure.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Orlando, FL to San Antonio, FL covers 68.7 miles and takes about 1h 39m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are FL 50, Treiman Boulevard, East-West Expressway. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 34.4 miles from Orlando, FL. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $10.94 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Leave by 9 AM and you'll arrive before lunch. Even a 4 PM departure gets you there before dark in summer.
This drive requires moderate attention. Across 68.7 miles you will encounter 12 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
The main spots that need attention: at 9.5 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 16.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 16.5 miles: Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
Between Orlando, FL and San Antonio, FL, road signs point toward Florida's Turnpike North, Ocala, Clermont and Winter Garden.
How this page is built
Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, NREL for EV charging, and NPS for national parks. See our methodology for refresh cadence and limitations.
