The drive from Oxford, MS to Booneville, MS covers 322.9 miles and takes about 6h 35m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on MS Hwy 25, I 55, MS 25 for much of the mileage,
and the overall profile is highway-focused drive.
The longest uninterrupted segment is about 79.6 miles on MS Hwy 25.
At current regular gas prices, budget about $48.77 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
161.4 miles from Oxford, MS
A natural place for your longest stop of the day
, about 3h 23m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 6h 35m. Total distance: 322.9 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
6h 35m drive, plan rest stops for pacing.
Drive Character
This is a 6h 35m highway drive covering 322.9 miles, with most of the trip on MS Hwy 25 and I 55. The longest continuous stretch is about 79.6 miles on MS Hwy 25.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 29 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
MS Hwy 25 is the longest continuous segment at about 79.6 miles.
How Hard Is This Drive?
This is a straightforward highway drive that stays mostly on MS Hwy 25 and I 55. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 97.1 miles in near I 55.
Driving Effort8/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 18 significant decision points across 322.9 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 97.1 miles (I 55): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 218.4 miles (MS 25): Highway fork - watch signs carefully. Lane positioning matters here; at 224.6 miles (MS 25): Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Critical Maneuvers
5 of 18 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
6
97.1 mi into trip|~2h 8m in|I 55
Keep slight left at fork onto I 55 toward Grenada, Memphis
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward Grenada, Memphis
6
218.4 mi into trip|~4h 28m in|MS 25
Keep slight right at fork onto MS 25
Highway fork - watch signs carefully. Lane positioning matters here
Use the left lane.
6
224.6 mi into trip|~4h 35m in|MS 25
Keep slight right at fork onto MS 25 toward US 82 East, MS 25 North: Columbus, West Point
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward US 82 East, MS 25 North: Columbus, West...
6
293.1 mi into trip|~5h 58m in|US 45
Keep slight right at fork onto US 45
Highway fork - watch signs carefully. Lane positioning matters here
Use the straight / slight left lanes.
6
320.1 mi into trip|~6h 30m in
Keep slight right at fork toward Booneville
Highway fork - watch signs carefully
Toward Booneville
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Oxford, MS and Booneville, MS, road signs point toward Grenada, Memphis, Point and Tupelo.
Grenada
97.1 mi in|~2h 8m|via I 55
Memphis
97.1 mi in|~2h 8m|via I 55
Point
224.6 mi in|~4h 35m|via MS 25
Tupelo
236.9 mi in|~4h 49m
Main Roads
Road
Distance
Duration
MS Hwy 25
79.6 mi
1h 30m
I 55
59.5 mi
1h 4m
MS 25
43.5 mi
50m
US Highway 45 Alternate
34.6 mi
42m
US 45
25.8 mi
29m
US 84
22.9 mi
26m
Martin Luther King Drive
18.1 mi
20m
Lakeland Drive
12.3 mi
14m
Longest stretch:
MS Hwy 25
— 79.6 mi, about 1h 30m
Turn-by-Turn Driving Directions
Step-by-step road directions between Oxford, MS and Booneville, MS.
1
Start on Oxford-Meadville Road
6.3 mi·15 min·Oxford-Meadville Road
2
Continue on Gloster Road
2.8 mi·6 min·Gloster Road
3
At end of road, turn left onto Gloster Road
3.8 mi·9 min·Gloster Road
4
Continue on Yap 3 Road
2.6 mi·6 min·Yap 3 Road
5
Turn left onto US 98
1.8 mi·2 min·United States Highway 98
6
Turn right onto MS 184
1.4 mi·2 min·Old US Hwy 84
7
Turn right onto US 84
23 mi·26 min·US 84
8
Take the exit
0.2 mi·27 sec
9
Merge onto I 55
53 mi·57 min·I 55
10
Keep slight right at fork onto I 55
2.1 mi·2 min·I 55
11
Keep slight left at fork onto I 55
4.2 mi·5 min·I 55
Toward Grenada, Memphis
12
Take the exit
0.2 mi·27 sec
Toward MS 25 North: Carthage
13
Turn right onto MS 25
12 mi·14 min·Lakeland Drive
14
Continue on MS 25
80 mi·1 hr 30 min·MS Hwy 25
15
Take the exit onto MS 25
25 mi·29 min·MS 25
16
Keep slight right at fork onto MS 25
2.4 mi·2 min·MS 25
Use the left lane.
17
Continue on MS 25
3.8 mi·4 min·MS 25
18
Keep slight right at fork onto MS 25
12 mi·13 min·MS 25
Toward US 82 East, MS 25 North: Columbus, West Point
19
Take the exit
0.3 mi·34 sec
Toward US 45 Alternate North, MS 25 North: West Point, Tupelo
20
Merge onto US 45 ALT; MS 25
35 mi·42 min·US Highway 45 Alternate
Use the straight lane.
21
Continue on US 45 ALT
18 mi·20 min·Martin Luther King Drive
22
Continue on US 45; MS 6
3.3 mi·4 min·Martin Luther King, Junior Drive
Use the straight / slight right lanes.
23
Keep slight right at fork onto US 45
26 mi·29 min·US 45
Use the straight / slight left lanes.
24
Take the exit onto MS 30
1.0 mi·1 min·MS 30
Toward MS 30 East: South Booneville, Tishomingo
25
Turn slight right
0.2 mi·34 sec
Toward MS 145: Booneville
26
Keep slight right at fork
226 ft·8 sec
Toward Booneville
27
Turn straight onto MS 145
2.8 mi·4 min·South 2nd Street
28
Turn right onto Washington Street
28 ft·0 sec·Washington Street
29
Arrive at destination
Washington Street
Trip Plan
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 161.4 miles from Oxford, MS, or about 3h 23m into the drive.
The longest continuous stretch on this route runs about 79.6 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 71 miles or 1h 40m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 161.4 miles or 3h 23m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 5h 24m
Traffic, exits, and arrival timing usually matter more near Booneville, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving Oxford, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Oxford, MS
This is one driving day of about 322.9 miles and 6h 35m.
Your first comfortable stop window is around 71 miles from Oxford, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on MS Hwy 25 for about 79.6 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 161.4 mi from Oxford, MS
· 3h 23m into the drive
The midpoint is around 161.4 miles from Oxford, MS, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel check
Top up before MS Hwy 25 if your tank is already low. That segment runs about 79.6 miles.
Arriving in Booneville, MS
The final approach into Booneville, MS usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Booneville, MS.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
National Parks Near This Route
Worth a detour if your schedule allows.
Natchez Trace National Scenic Trail
National Scenic Trail
The Natchez Trace National Scenic Trail is five sections of hiking trail running roughly parallel to the 444-mile long Natchez Trace Parkway scenic motor road. The foot trails total more than 60 miles...
3 mi from route
~9 min detour
Free
near mile 300.6
Park Closure: Partial Closure of Rocky Springs Trail
Park Closure: Temporary Blackland Prairie Trail Closure to Equestrians
In July, 1864, federal forces, including men from the United States Colored Troops, marched into Tupelo, Mississippi. Disorganized Confederate soldiers fought fiercely but could not overpower the fede...
3 mi from route
~7 min detour
Free
near mile 289.5
Medgar and Myrlie Evers were partners in the civil rights struggle. The assassination of Medgar Evers in the carport of their home on June 12, 1963, was the first murder of a nationally significant le...
4 mi from route
~9 min detour
Free
near mile 100.2
Discover the history of all the peoples of Natchez, Mississippi, from European settlement, African enslavement, the American cotton economy, to the Civil Rights struggle on the lower Mississippi River...
30 mi from route
~75 min detour
Free
near mile 11.1
Park data from the National Park Service API. Alerts update every 2 hours.
Fuel & Cost
Regular Gas
$48.77 one way
$97.53 round trip
$3.84/gal25.4 MPG avg113 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.21
$53.53
$107.07
premium
$4.56
$57.96
$115.91
diesel
$5.61
$71.29
$142.58
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$49
Meals
$25–$50
Total
$74–$99
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 113 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $34 in charging
· 1 stop
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
96.9
1
$33.90
$15.50
Efficient EV
80.7
0
$28.25
$12.92
EV Truck/SUV
129.2
1
$45.21
$20.67
Gas CO2
113 kg
EV CO2
38 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Oxford, MS
Afternoon
in Oxford on Friday
Local time
4:48 PM
CDT
Current temp
80°F
Unavailable
Live forecast
Destination
Booneville, MS
Afternoon
in Booneville on Friday
Local time
4:48 PM
CDT
Current temp
77°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
3 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
6h 35m on the road
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Oxford, MS to Booneville, MS covers 322.9 miles and takes about 6h 35m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are MS Hwy 25, I 55, MS 25. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 161.4 miles from Oxford, MS. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $48.77 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 18 significant decision points across 322.9 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 97.1 miles (I 55): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 218.4 miles (MS 25): Highway fork - watch signs carefully. Lane positioning matters here; at 224.6 miles (MS 25): Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Between Oxford, MS and Booneville, MS, road signs point toward Grenada, Memphis, Point and Tupelo.
Yes. Nearby national parks include Natchez Trace National Scenic Trail, Tupelo National Battlefield and Medgar and Myrlie Evers Home National Monument. There are 4 parks within detour distance of this route.
How this page is built
Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.
