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Trip from Oxford, MS to Itawamba County, MS

Last recalculated Apr 16, 2026

Drive Time

6h 28m

Distance

314.9 mi

507 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$48

one way

EV Charging

Unknown

Best Time to Leave

Save up to 37 min
4 AM
6h 16m ★
6 AM
6h 28m
8 AM
6h 53m
10 AM
6h 37m
12 PM
6h 35m
3 PM
6h 38m
5 PM
6h 52m
8 PM
6h 21m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

city in Oxfordshire, England

Oxford, MS

Wikimedia Commons

Downtown Itawamba County, MS, MS

Itawamba County, MS

Mark Stebnicki

Trip Overview

The drive from Oxford, MS to Itawamba County, MS covers 314.9 miles and takes about 6h 28m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on MS Hwy 25, I 55, MS 25 for much of the mileage, and the overall profile is highway-focused drive. The longest uninterrupted segment is about 79.6 miles on MS Hwy 25. At current regular gas prices, budget about $47.56 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

157.5 miles from Oxford, MS

A natural place for your longest stop of the day , about 3h 18m into the drive .

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 6h 28m. Total distance: 314.9 miles.

Family Friendly

Moderate complexity with 1 natural rest stops along the way.

Solo Traveler

6h 28m drive, plan rest stops for pacing.

Drive Character

This is a 6h 28m highway drive covering 314.9 miles, with most of the trip on MS Hwy 25 and I 55. The longest continuous stretch is about 79.6 miles on MS Hwy 25.

Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 31 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
MS Hwy 25 is the longest continuous segment at about 79.6 miles.

How Hard Is This Drive?

This is a straightforward highway drive that stays mostly on MS Hwy 25 and I 55. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 97.1 miles in near I 55.

Driving Effort 8/10

Demanding - plan breaks and stay ahead of the key maneuvers

Balances navigation complexity with total wheel time.

This is a demanding drive. With 18 significant decision points across 314.9 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: at 97.1 miles (I 55): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 218.4 miles (MS 25): Highway fork - watch signs carefully. Lane positioning matters here; at 224.6 miles (MS 25): Highway fork - watch signs carefully. Multiple destination signs - pick the right one.

Critical Maneuvers

5 of 18 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

6
97.1 mi into trip | ~2h 8m in | I 55

Keep slight left at fork onto I 55 toward Grenada, Memphis

Highway fork - watch signs carefully. Multiple destination signs - pick the right one

Toward Grenada, Memphis
6
218.4 mi into trip | ~4h 28m in | MS 25

Keep slight right at fork onto MS 25

Highway fork - watch signs carefully. Lane positioning matters here

Use the left lane.
6
224.6 mi into trip | ~4h 35m in | MS 25

Keep slight right at fork onto MS 25 toward US 82 East, MS 25 North: Columbus, West Point

Highway fork - watch signs carefully. Multiple destination signs - pick the right one

Toward US 82 East, MS 25 North: Columbus, West...
5
236.9 mi into trip | ~4h 49m in

Take the exit toward US 45 Alternate North, MS 25 North: West Point, Tupelo

Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one

Toward US 45 Alternate North, MS 25 North: West...
5
237.2 mi into trip | ~4h 50m in | US 45 ALT; MS 25 / US Highway 45 Alternate

Merge onto US 45 ALT; MS 25 / US Highway 45 Alternate

Merge point - match speed before joining. Lane positioning matters here

Use the straight lane.

Towns Mentioned on Route Signs

Based on OSRM destination-sign hints, not a full list of every settlement the road passes.

Between Oxford, MS and Itawamba County, MS, road signs point toward Grenada, Memphis, Point and Tupelo.

Grenada

97.1 mi in | ~2h 8m | via I 55

Memphis

97.1 mi in | ~2h 8m | via I 55

Point

224.6 mi in | ~4h 35m | via MS 25

Tupelo

236.9 mi in | ~4h 49m

Main Roads

Road Distance Duration
MS Hwy 25 79.6 mi 1h 30m
I 55 59.5 mi 1h 4m
MS 25 43.5 mi 50m
US Highway 45 Alternate 34.6 mi 42m
US 84 22.9 mi 26m
Martin Luther King Drive 18.1 mi 20m
I 22 14.3 mi 15m
Lakeland Drive 12.3 mi 14m
Longest stretch: MS Hwy 25 — 79.6 mi, about 1h 30m

Turn-by-Turn Driving Directions

Step-by-step road directions between Oxford, MS and Itawamba County, MS.

1

Start on Oxford-Meadville Road

6.3 mi · 15 min · Oxford-Meadville Road
2

Continue on Gloster Road

2.8 mi · 6 min · Gloster Road
3

At end of road, turn left onto Gloster Road

3.8 mi · 9 min · Gloster Road
4

Continue on Yap 3 Road

2.6 mi · 6 min · Yap 3 Road
5

Turn left onto US 98

1.8 mi · 2 min · United States Highway 98
6

Turn right onto MS 184

1.4 mi · 2 min · Old US Hwy 84
7

Turn right onto US 84

23 mi · 26 min · US 84
8

Take the exit

0.2 mi · 27 sec
9

Merge onto I 55

53 mi · 57 min · I 55
10

Keep slight right at fork onto I 55

2.1 mi · 2 min · I 55
11

Keep slight left at fork onto I 55

4.2 mi · 5 min · I 55
Toward Grenada, Memphis
12

Take the exit

0.2 mi · 27 sec
Toward MS 25 North: Carthage
13

Turn right onto MS 25

12 mi · 14 min · Lakeland Drive
14

Continue on MS 25

80 mi · 1 hr 30 min · MS Hwy 25
15

Take the exit onto MS 25

25 mi · 29 min · MS 25
16

Keep slight right at fork onto MS 25

2.4 mi · 2 min · MS 25
Use the left lane.
17

Continue on MS 25

3.8 mi · 4 min · MS 25
18

Keep slight right at fork onto MS 25

12 mi · 13 min · MS 25
Toward US 82 East, MS 25 North: Columbus, West Point
19

Take the exit

0.3 mi · 34 sec
Toward US 45 Alternate North, MS 25 North: West Point, Tupelo
20

Merge onto US 45 ALT; MS 25

35 mi · 42 min · US Highway 45 Alternate
Use the straight lane.
21

Continue on US 45 ALT

18 mi · 20 min · Martin Luther King Drive
22

Take the exit

0.3 mi · 38 sec
Toward Eason Boulevard
23

Turn straight onto South Eason Boulevard

4.9 mi · 7 min · South Eason Boulevard
24

Continue on CR 931

0.1 mi · 20 sec · Auburn Road
25

Take the ramp

0.3 mi · 45 sec
26

Merge onto I 22; US 78

14 mi · 15 min · I 22; US 78
27

Take the exit

0.3 mi · 41 sec
Toward Fulton, Amory
28

Turn slight left onto South Adams Street

2.2 mi · 3 min · South Adams Street
29

Turn right onto MS 178

2.4 mi · 4 min · East Main Street
30

Turn left onto Walton Road Southwest

0.2 mi · 35 sec · Walton Road Southwest
31

Arrive at destination

Walton Road Southwest

Trip Plan

Morning Departure

Start early — leave by 6-7 AM to arrive at a reasonable hour.

Evening Departure

This is a long drive — plan for a morning departure or consider splitting it into two days.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 157.5 miles from Oxford, MS, or about 3h 18m into the drive.
The longest continuous stretch on this route runs about 79.6 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 69 miles or 1h 38m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 157.5 miles or 3h 18m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 5h 16m

Traffic, exits, and arrival timing usually matter more near Itawamba County, MS than in the middle of the route.

Before You Leave

+

Open the route before leaving Oxford, MS so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Oxford, MS

This is one driving day of about 314.9 miles and 6h 28m.

Your first comfortable stop window is around 69 miles from Oxford, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on MS Hwy 25 for about 79.6 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 157.5 mi from Oxford, MS · 3h 18m into the drive

city in Stone County, Mississippi, United States

Mid-route town

Meal stop

Wiggins, MS

157 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Florence, MS

Fuel and coffee

A short stop after about 69 miles helps settle the day before fatigue starts building.

Wiggins, MS

Meal break

The midpoint is around 157.5 miles from Oxford, MS, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before MS Hwy 25 if your tank is already low. That segment runs about 79.6 miles.

Arriving in Itawamba County, MS

The final approach into Itawamba County, MS usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Itawamba County, MS.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$47.56 one way

$95.11 round trip

$3.84/gal 25.4 MPG avg 110 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.21 $52.21 $104.41
premium $4.56 $56.52 $113.04
diesel $5.61 $69.53 $139.05

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$48

Meals

$25–$50

Total

$73–$98

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 110.2 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $33 in charging · 1 stop · 66% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 94.5 1 $33.06 $15.12
Efficient EV 78.7 0 $27.55 $12.60
EV Truck/SUV 126 1 $44.09 $20.15

Gas CO2

110 kg

EV CO2

37 kg (66% less)

Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 15, 2026

Origin

Oxford, MS

Afternoon in Oxford on Thursday

Local time

2:51 PM

CDT

Current temp

80°F

Unavailable

Live forecast

Destination

Itawamba County, MS

Afternoon in Itawamba County on Thursday

Local time

2:51 PM

CDT

Current temp

79°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

1 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

6h 28m on the road

Start early — leave by 6-7 AM to arrive at a reasonable hour.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Oxford, MS to Itawamba County, MS covers 314.9 miles and takes about 6h 28m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are MS Hwy 25, I 55, MS 25. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 157.5 miles from Oxford, MS. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $47.56 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 18 significant decision points across 314.9 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 97.1 miles (I 55): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 218.4 miles (MS 25): Highway fork - watch signs carefully. Lane positioning matters here; at 224.6 miles (MS 25): Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Between Oxford, MS and Itawamba County, MS, road signs point toward Grenada, Memphis, Point and Tupelo.

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Explore More

Return Trip

Itawamba County, MS to Oxford, MS

Plan the drive back the other way.

315.5 mi 6h 29m

Explore more options from Oxford, MS or browse trips ending in Itawamba County, MS.

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Explore maps for Oxford, MS or Itawamba County, MS on MapSof.net.