Trip from Oxford, MS to Biloxi, MS

Drive Time

6h 20m

Distance

323.7 mi

521 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$49

one way

EV Charging

Excellent

32 DC fast

Best Time to Leave

Save up to 37 min

4 AM

6h 8m ★

6 AM

6h 20m

8 AM

6h 45m

10 AM

6h 29m

12 PM

6h 27m

3 PM

6h 30m

5 PM

6h 44m

8 PM

6h 13m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Best Time Drive vs Fly

Google Maps Waze Apple Maps

Download GPX

Oxford, MS

Shaun Iwasawa

Biloxi, MS

大董

Trip Overview

The drive from Oxford, MS to Biloxi, MS covers 323.7 miles and takes about 6h 20m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on MS 7, Highway 49 South, US 49 for much of the mileage, and the overall profile is highway-focused drive. The longest uninterrupted segment is about 144.2 miles on MS 7. At current regular gas prices, budget about $49.49 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

161.8 miles from Oxford, MS

A natural place for your longest stop of the day , about 3h 2m into the drive .

Drive Character

This is a 6h 20m highway drive covering 323.7 miles, with most of the trip on MS 7 and Highway 49 South. The longest continuous stretch is about 144.2 miles on MS 7.

Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.

There are about 31 navigation steps in the underlying route data, so the final approach matters more than the middle miles.

MS 7 is the longest continuous segment at about 144.2 miles.

How Hard Is This Drive?

This is a straightforward highway drive that stays mostly on MS 7 and Highway 49 South. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 161.7 miles in near US 49.

Route Complexity 9/10

High effort - long or complex enough to need steady focus all day

This is a demanding drive. With 20 significant decision points across 323.7 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: at 161.7 miles (US 49): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 244.2 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 252.3 miles (US 98): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.

Critical Maneuvers

5 of 20 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

161.7 mi into trip | ~3h 1m in | US 49

Keep slight right at fork onto US 49 toward Richland, Hattiesburg

Highway fork - watch signs carefully. Multiple destination signs - pick the right one

Toward Richland, Hattiesburg

244.2 mi into trip | ~4h 43m in

Take the exit toward I 59 South: New Orleans, Gulf Coast

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Toward I 59 South: New Orleans, Gulf Coast

252.3 mi into trip | ~4h 52m in | US 98

Take the exit onto US 98 toward US 98 East: Lucedale, Mobile

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the straight / slight right lanes. Toward US 98 East: Lucedale, Mobile

255.5 mi into trip | ~4h 56m in

Take the exit toward US 49: Wiggins, Gulfport, Mississippi Gulf Coast

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the straight / slight right lanes. Toward US 49: Wiggins, Gulfport, Mississippi Gu...

255.8 mi into trip | ~4h 56m in

Keep slight left at fork toward Multi Purpose Center, Hattiesburg

Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight left / slight right lanes. Toward Multi Purpose Center, Hattiesburg

Towns Along This Route

Between Oxford, MS and Biloxi, MS, road signs point toward Hattiesburg, Richland, Gulf Coast, Mississippi Gulf Coast, Mobile and Gulfport - among others.

Hattiesburg

160.8 mi in | ~3h

Richland

161.7 mi in | ~3h 1m | via US 49

Gulf Coast

244.2 mi in | ~4h 43m

Mississippi Gulf Coast

244.6 mi in | ~4h 43m | via I 59

Mobile

252.3 mi in | ~4h 52m | via US 98

Gulfport

255.5 mi in | ~4h 56m

Multi Purpose Center

255.8 mi in | ~4h 56m

Main Roads

Road	Distance	Duration
MS 7	144.2 mi	2h 39m
Highway 49 South	80.3 mi	1h 37m
US 49	44.1 mi	53m
Biloxi-D'Iberville Scenic Expressway	20.5 mi	24m
I 55	15.6 mi	18m
Lance Corporal Roy M Wheat Memorial Highway	7.7 mi	8m
US 98	3.2 mi	4m
I 110	3.2 mi	4m

Longest stretch: MS 7 — 144.2 mi, about 2h 39m

Turn-by-Turn Driving Directions

Step-by-step road directions between Oxford, MS and Biloxi, MS.

Start on Courthouse Square

148 ft · 11 sec · Courthouse Square

Continue on Courthouse Square

92 ft · 4 sec · Courthouse Square

Turn right

55 ft · 2 sec

Turn right onto South Lamar Boulevard

0.1 mi · 26 sec · South Lamar Boulevard

Turn left onto MS 314

0.7 mi · 1 min · University Avenue

Enter roundabout

36 ft · 0 sec

Continue

0.2 mi · 19 sec

Merge onto MS 7

6.8 mi · 9 min · MS 7

Enter roundabout onto MS 7

124 ft · 1 sec · MS 7

Toward MS 7 South: Water Valley

Continue on MS 7

36 mi · 41 min · MS 7

Toward MS 7 South: Water Valley

Take the exit onto MS 7

101 mi · 1 hr 48 min · MS 7

Continue on I 55

16 mi · 18 min · I 55

Take the exit

0.9 mi · 1 min

Toward I 20 East, US 49 South: Meridian, Hattiesburg

Keep slight right at fork onto US 49

0.7 mi · 1 min · US 49

Toward Richland, Hattiesburg

Merge onto US 49

80 mi · 1 hr 37 min · Highway 49 South

Use the straight lane.

Continue on US 49; MS 42

0.4 mi · 35 sec · US 49; MS 42

Use the straight lane.

Continue on US 49; MS 42

1.1 mi · 1 min · US 49; MS 42

Use the straight lane.

Take the exit

0.4 mi · 36 sec

Toward I 59 South: New Orleans, Gulf Coast Use the slight right lane.

Merge onto I 59

7.7 mi · 8 min · Lance Corporal Roy M Wheat Memorial Highway

Toward Mississippi Gulf Coast Use the straight lane.

Take the exit onto US 98

3.2 mi · 4 min · US 98

Toward US 98 East: Lucedale, Mobile Use the straight / slight right lanes.

Take the exit

0.3 mi · 44 sec

Toward US 49: Wiggins, Gulfport, Mississippi Gulf Coast Use the straight / slight right lanes.

Keep slight left at fork

0.2 mi · 27 sec

Toward Multi Purpose Center, Hattiesburg Use the slight left / slight right lanes.

Turn right onto US 49

42 mi · 49 min · US 49

Use the straight lane.

Take the exit

0.8 mi · 1 min

Toward MS 67 South: D'Iberville, Biloxi

Continue on MS 67

20 mi · 24 min · Biloxi-D'Iberville Scenic Expressway

Continue on I 110

3.2 mi · 4 min · I 110

Take the exit

0.4 mi · 47 sec

Exit 1c Toward Division Street

Turn left onto Division Street

0.6 mi · 1 min · Division Street

Turn right onto Main Street

0.5 mi · 1 min · Main Street

Turn left onto Howard Avenue

91 ft · 3 sec · Howard Avenue

Arrive at destination

Howard Avenue

Trip Plan

Morning Departure

Start early — leave by 6-7 AM to arrive at a reasonable hour.

Evening Departure

This is a long drive — plan for a morning departure or consider splitting it into two days.

You can normally do this drive in one day.

Plan roughly 1 meaningful break for fuel, food, and rest.

The halfway point lands around 161.8 miles from Oxford, MS, or about 3h 2m into the drive.

The longest continuous stretch on this route runs about 144.2 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 80 miles or 1h 31m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 161.8 miles or 3h 2m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 5h 8m

Traffic, exits, and arrival timing usually matter more near Biloxi, MS than in the middle of the route.

Before You Leave

Open the route before leaving Oxford, MS so your first major turns are already loaded.

Leave with enough water and a charging cable within reach, not packed away.

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Oxford, MS

This is one driving day of about 323.7 miles and 6h 20m.

Your first comfortable stop window is around 80 miles from Oxford, MS.

This route can stay practical as a one-day drive if traffic stays reasonable.

Plan about 1 real break rather than only quick fuel stops.

The longest stretch is on MS 7 for about 144.2 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 161.8 mi from Oxford, MS · 3h 2m into the drive

Mid-route town

Meal stop

Magee, MS

162 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Popular next leg

Magee, MS to Biloxi, MS

122.3 mi · 2h 29m

Pacing Suggestions

Magee, MS

Fuel and coffee

A short stop after about 80 miles helps settle the day before fatigue starts building.

Magee, MS

Meal break

The midpoint is around 161.8 miles from Oxford, MS, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before MS 7 if your tank is already low. That segment runs about 144.2 miles.

Arriving in Biloxi, MS

The final approach into Biloxi, MS usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Biloxi, MS.

After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

National Parks Near This Route

Worth a detour if your schedule allows.

Medgar and Myrlie Evers Home National Monument

National Monument

Medgar and Myrlie Evers were partners in the civil rights struggle. The assassination of Medgar Evers in the carport of their home on June 12, 1963, was the first murder of a nationally significant le...

3 mi from route ~8 min detour Free near mile 156.3

View on nps.gov

Park data from the National Park Service API. Alerts update every 2 hours.

Fuel & Cost

Regular Gas

$49.49 one way

$98.97 round trip

$3.88/gal 25.4 MPG avg 113 kg CO₂

Fuel Type	$/gal	One Way	Round Trip
midgrade	$4.26	$54.28	$108.55
premium	$4.61	$58.75	$117.50
diesel	$5.64	$71.91	$143.83

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$49

Meals

$25–$50

Total

$74–$99

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 113.3 kg one way. Prices: EIA weekly data, 2026-04-06.

EV Charging Along Route

32 DC fast chargers · Coverage: excellent

North Bus Barn

Jackson, MS

NOODOE

14 DCFC

South Bus Barn

Jackson, MS

NOODOE

12 DCFC

Lakeview Village Shopping Mall - Tesla Supercharger

D'Iberville, MS

Tesla

12 DCFC

Sayle C-Store - Tesla Supercharger

Grenada, MS

Tesla

8 DCFC

Outlets of Mississippi - Tesla Supercharger

Pearl, MS

Tesla

8 DCFC

Cracker Barrel - Tesla Supercharger

Hattiesburg, MS

Tesla

8 DCFC

Turtle Creek Crossing - Tesla Supercharger

Hattiesburg, MS

Tesla

8 DCFC

Electric Era Charging Station

Water Valley, MS

ELECTRIC_ERA

4 DCFC

EV Connect: 8 ChargePoint Network: 8 Tesla: 5 NOODOE: 3 eVgo Network: 2 RED_E: 2 ELECTRIC_ERA: 1 FORD_CHARGE: 1 Blink Network: 1 Non-Networked: 1

Station data from NREL Alternative Fuel Stations database.

Driving Electric?

About $34 in charging · 1 stop · 66% less CO₂

Vehicle Type	kWh	Stops	DC Fast	Home Charge
Average EV	97.1	1	$33.99	$15.54
Efficient EV	80.9	0	$28.32	$12.95
EV Truck/SUV	129.5	1	$45.32	$20.72

Gas CO2

113 kg

EV CO2

38 kg (66% less)

Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast data refreshed 1 hour ago

Origin

Oxford, MS

Evening in Oxford on Sunday

Local time

7:03 PM

CDT

Current temp

84°F

Mostly Sunny

S 15 mph 1% chance Live forecast

Destination

Biloxi, MS

Evening in Biloxi on Sunday

Local time

7:03 PM

CDT

Current temp

64°F

Mostly Cloudy

SE 5 to 10 mph 0% chance Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

20 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

6h 20m on the road

Start early — leave by 6-7 AM to arrive at a reasonable hour.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Oxford, MS to Biloxi, MS covers 323.7 miles and takes about 6h 20m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.

The main roads are MS 7, Highway 49 South, US 49. Most of the drive stays on highways, so watch for ramps and exits.

This is a comfortable same-day trip.

The midpoint is about 161.8 miles from Oxford, MS. Look for rest areas, gas stations, or food options near the halfway mark.

At current regular gas prices, expect to spend about $49.49 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.

Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.

Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Between Oxford, MS and Biloxi, MS, road signs point toward Hattiesburg, Richland, Gulf Coast, Mississippi Gulf Coast, Mobile and Gulfport - among others.

Was this route helpful?

Thanks for your feedback!

Your tip has been submitted. Thanks!

/500

Explore More

Explore more options from Oxford, MS or browse trips ending in Biloxi, MS.

Looking for more statewide routes? Browse MS road trips.

Explore maps for Oxford, MS or Biloxi, MS on MapSof.net.

Trip from Oxford, MS to Biloxi, MS

Best Time to Leave

Trip Overview

Drive Character

How Hard Is This Drive?

Critical Maneuvers

Towns Along This Route

Main Roads

Turn-by-Turn Driving Directions

Trip Plan

Before You Leave

Where to Stop

Pacing Suggestions

Arriving in Biloxi, MS

National Parks Near This Route

Medgar and Myrlie Evers Home National Monument

Fuel & Cost

Travel Intel

Oxford, MS

Biloxi, MS

Same local time

20 degrees cooler at arrival

6h 20m on the road

Frequently Asked Questions

Was this route helpful?

Explore More

Continue From Biloxi, MS

More from Oxford, MS

More trips to Biloxi, MS