Pamplico, SC to North Charleston, SC is 99.5 miles and takes about 2h 23m via South Williamsburg County Highway and Goose Creek Boulevard South, with a fuel budget near $16 and enough daylight to finish in a day. This drive stays within the Southeast region, connecting two points in South Carolina. Expect a local feel for most of the journey, with a significant portion on county roads. Given its relatively short length and manageable duration, this route is ideal for a same-day trip, allowing for a relaxed departure or arrival.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Midpoint
49.7 miles from Pamplico, SC
A natural place for your longest stop of the day
, about 1h 18m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 2h 23m. Total distance: 99.5 miles.
Family Friendly
Moderate complexity with 0 natural rest stops along the way.
Turn-heavy local drive route profile with national parks nearby.
Drive Character
This route is characterized as a 'turn-heavy local drive,' with only an 8% share of highway driving. You'll primarily navigate South Williamsburg County Highway, Goose Creek Boulevard South, and North Williamsburg County Highway. The longest uninterrupted stretch you'll encounter is 37.7 miles along South Williamsburg County Highway, offering a consistent local road experience for a significant segment. The road's personality leans towards frequent turns and local traffic rather than high-speed travel.
This route has more turning and local-road decision points than a simple highway run.
There are about 22 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
South Williamsburg County Highway is the longest continuous segment at about 37.7 miles.
How Hard Is This Drive?
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. There are only a few real navigation decisions along the way. The trickiest moment comes around 5.9 miles in near South Friendfield Road.
Driving Effort3/10
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
This is a straightforward 2h 23m drive. You will face about 9 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
The main spots that need attention: at 5.9 miles (South Friendfield Road): Navigation decision point; at 10.1 miles (US 378): Navigation decision point; at 18.1 miles (US 52 / South Ron McNair Boulevard): Navigation decision point.
Critical Maneuvers
5 of 9 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
5
5.9 mi into trip|~13m in|South Friendfield Road
At end of road, turn left onto South Friendfield Road
Navigation decision point
4
10.1 mi into trip|~23m in|US 378
At end of road, turn right onto US 378
Navigation decision point
4
18.1 mi into trip|~34m in|US 52 / South Ron McNair Boulevard
Turn left onto US 52 / South Ron McNair Boulevard
Navigation decision point
4
33.4 mi into trip|~56m in|US 52; SC 261 / West Main Street
Turn right onto US 52; SC 261 / West Main Street
Navigation decision point
6
79.2 mi into trip|~1h 57m in|US 52 / Goose Creek Boulevard South
Keep slight right at fork onto US 52 / Goose Creek Boulevard South
Highway fork - watch signs carefully. Lane positioning matters here
Use the left lane.
Main Roads
Road
Distance
Duration
South Williamsburg County Highway
37.7 mi
49m
Goose Creek Boulevard South
17.2 mi
19m
North Williamsburg County Highway
11.1 mi
13m
Rivers Avenue
8.2 mi
12m
US 378
5.5 mi
6m
South Friendfield Road
4.2 mi
10m
Hyman Road
4 mi
9m
South Ron McNair Boulevard
2.5 mi
4m
Longest stretch:
South Williamsburg County Highway
— 37.7 mi, about 49m
Turn-by-Turn Driving Directions
Step-by-step road directions between Pamplico, SC and North Charleston, SC.
1
Start on State Road S-21-132
40 ft·8 sec·North Walnut Street
2
Continue on North Walnut Street
75 ft·4 sec·North Walnut Street
3
Turn right onto SC 51
1.9 mi·3 min·North Pamplico Highway
4
Turn left onto Hyman Road
4.0 mi·9 min·Hyman Road
5
At end of road, turn left onto South Friendfield Road
4.2 mi·10 min·South Friendfield Road
6
At end of road, turn right onto US 378
5.5 mi·6 min·US 378
7
Turn left onto US 378 Business
1.1 mi·1 min·East Myrtle Beach Highway
8
Continue on US 378 Business
0.8 mi·1 min·North Church Street
9
Turn right onto East Thomas Street
0.4 mi·1 min·East Thomas Street
10
Turn left onto US 52
2.5 mi·4 min·South Ron McNair Boulevard
11
Continue on US 52
11 mi·13 min·North Williamsburg County Highway
12
Continue on US 52
1.7 mi·3 min·Longstreet Street
13
Turn right onto US 52; SC 261
0.2 mi·10 sec·West Main Street
14
Continue on US 52; SC 261
38 mi·49 min·South Williamsburg County Highway
15
Continue on US 17 Alternate; US 52
0.6 mi·1 min·US 17 Alternate; US 52
16
Continue on US 52; US 17 Alternate
1.1 mi·2 min·US 52; US 17 Alternate
17
Continue on US 52; SC 6 Truck
1.2 mi·1 min·US 52; SC 6 Truck
18
Continue on US 52
5.2 mi·5 min·Goose Creek Boulevard South
Use the left lane.
19
Keep slight right at fork onto US 52
12 mi·13 min·Goose Creek Boulevard South
Use the left lane.
20
Continue on US 52; US 78
0.2 mi·15 sec·Rivers Avenue
21
Continue on US 52; US 78
8.0 mi·12 min·Rivers Avenue
22
Arrive at destination
US 52; US 78
Trip Plan
Given this is a single-day trip covering 99.5 miles and taking just over two hours, flexibility is your best friend. You can depart in the morning and arrive by midday, or even leave in the afternoon. Since the longest stretch is 37.7 miles, plan for a brief stop around that point if you prefer to break up the driving. Keep an eye on your fuel gauge, especially before heading out, as the estimated fuel cost is $16, and local roads can sometimes mean less frequent services than major highways.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 49.7 miles from Pamplico, SC, or about 1h 18m into the drive.
The longest continuous stretch on this route runs about 37.7 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 22 miles or 40m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 49.7 miles or 1h 18m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 1h 59m
Traffic, exits, and arrival timing usually matter more near North Charleston, SC than in the middle of the route.
Before You Leave
+
Open the route before leaving Pamplico, SC so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Pamplico, SC
This is one driving day of about 99.5 miles and 2h 23m.
Your first comfortable stop window is around 22 miles from Pamplico, SC.
This route can stay practical as a one-day drive if traffic stays reasonable.
The longest stretch is on South Williamsburg County Highway for about 37.7 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 49.7 mi from Pamplico, SC
· 1h 18m into the drive
The midpoint is around 49.7 miles from Pamplico, SC, which is a good place for a longer meal and fuel stop.
Arriving in North Charleston, SC
The final approach into North Charleston, SC usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around North Charleston, SC.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Nearby Places
Restaurants, cafes, gas stations and more along your route.
Top Restaurant
Prophet Coffee
4.8
★ ★ ★ ★ ★
North Charleston, South Carolina
Near the end, short detour
1.5 mi from route
~4 min detour
$1 to $10
mile 99.5
Place data sourced from public business listings. Hours and availability may vary.
National Parks Near This Route
Worth a detour if your schedule allows.
Fort Sumter and Fort Moultrie National Historical Park
National Historical Park
Two forts stand at the entrance of Charleston Harbor. Patriots inside a palmetto log fort, later named Fort Moultrie, defeated the Royal Navy in 1776. As Charleston blazed a path towards secession to...
Park data from the National Park Service API. Alerts update every 2 hours.
Fuel & Cost
Regular Gas
$15.56 one way
$31.12 round trip
$3.97/gal25.4 MPG avg35 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.34
$17.01
$34.03
premium
$4.70
$18.42
$36.83
diesel
$5.61
$21.97
$43.94
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$16
Meals
$25–$50
Total
$41–$66
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 34.8 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $10 in charging
· 0 stops
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
29.8
0
$10.45
$4.78
Efficient EV
24.9
0
$8.71
$3.98
EV Truck/SUV
39.8
0
$13.93
$6.37
Gas CO2
35 kg
EV CO2
12 kg (66% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 17, 2026
Origin
Pamplico, SC
Afternoon
in Pamplico on Friday
Local time
3:59 PM
EDT
Current temp
90°F
Sunny
NW 3 mph0% chanceLive forecast
Destination
North Charleston, SC
Afternoon
in North Charleston on Friday
Local time
3:59 PM
EDT
Current temp
56°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
34 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
2h 23m on the road
The weather snapshot is not static. If you are leaving later, give both cities one more quick forecast check before departure.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Pamplico, SC to North Charleston, SC covers 99.5 miles and takes about 2h 23m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are South Williamsburg County Highway, Goose Creek Boulevard South, North Williamsburg County Highway. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 49.7 miles from Pamplico, SC. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $15.56 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Leave by 9 AM and you'll arrive before lunch. Even a 4 PM departure gets you there before dark in summer.
This is a straightforward 2h 23m drive. You will face about 9 decision points, but nothing that requires special attention if you follow navigation.
The main spots that need attention: at 5.9 miles (South Friendfield Road): Navigation decision point; at 10.1 miles (US 378): Navigation decision point; at 18.1 miles (US 52 / South Ron McNair Boulevard): Navigation decision point.
The route from Pamplico, SC to North Charleston, SC does not surface many named destination signs beyond the main corridor.
How this page is built
Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.
