This 293.1-mile drive from Pittsburgh, PA to Cherryville, PA will take approximately 5 hours and 50 minutes, making it a feasible day trip. With 67% of the route on highways, you'll experience a mostly high-speed journey. The estimated fuel cost for this trip is around $49. This route stays within the Northeast region, and its highway-focused profile means you can cover ground efficiently. You'll want to plan for at least one stop to break up the nearly 6-hour travel time.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
146.5 miles from Pittsburgh, PA
A natural place for your longest stop of the day
, about 2h 47m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 5h 50m. Total distance: 293.1 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
5h 50m drive, comfortable solo distance.
Drive Character
Expect a highway-focused drive on this route, with 67% of your journey utilizing major roadways. You'll spend a significant amount of time on the Pennsylvania Turnpike, including a continuous stretch of 170.5 miles. The drive predominantly follows major arteries like the Pennsylvania Turnpike, William Penn Highway, and American Legion Memorial Highway, suggesting a consistent pace. While primarily highway, the shift to roads like the William Penn Highway and American Legion Memorial Highway might offer slightly more varied scenery as you progress through Pennsylvania.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 31 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Pennsylvania Turnpike is the longest continuous segment at about 170.5 miles.
How Hard Is This Drive?
This is a straightforward highway drive that stays mostly on Pennsylvania Turnpike and William Penn Highway. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 14.7 miles in.
Driving Effort10/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 23 significant decision points across 293.1 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 14.7 miles: Highway fork - watch signs carefully. Lane positioning matters here; at 185.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 186.2 miles: Highway fork - watch signs carefully. Lane positioning matters here.
Critical Maneuvers
5 of 23 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
8
14.7 mi into trip|~22m in
Keep slight right at fork toward I 76 East: Harrisburg
Highway fork - watch signs carefully. Lane positioning matters here
Use the slight right lane.
Toward I 76 East: Harrisburg
7
185.3 mi into trip|~3h 30m in
Take the exit toward I 81, US 11: Carlisle, Harrisburg
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Toward I 81, US 11: Carlisle, Harrisburg
7
186.2 mi into trip|~3h 32m in
Keep slight left at fork toward US 11 North: Harrisburg
Highway fork - watch signs carefully. Lane positioning matters here
Use the straight / slight right lanes.
Toward US 11 North: Harrisburg
9
275.8 mi into trip|~5h 21m in|US 22 / Lehigh Valley Thruway
Keep slight right at fork onto US 22 / Lehigh Valley Thruway toward US 22 East: Pennsylvania Turnpike, LVI Airport
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 51
Toward US 22 East: Pennsylvania Turnpike, LVI A...
8
282.5 mi into trip|~5h 31m in
Keep slight left at fork toward PA 145 North: Whitehall
Highway fork - watch signs carefully. Lane positioning matters here
Use the left lane.
Toward PA 145 North: Whitehall
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Pittsburgh, PA and Cherryville, PA, road signs point toward Harrisburg, Marysville and Lvi Airport.
Harrisburg
185.3 mi in|~3h 30m
Marysville
200.5 mi in|~3h 51m
Lvi Airport
275.8 mi in|~5h 21m|via US 22
Main Roads
Road
Distance
Duration
Pennsylvania Turnpike
170.5 mi
3h 7m
William Penn Highway
42.8 mi
50m
American Legion Memorial Highway
22.5 mi
27m
Penn-Lincoln Parkway East
13.6 mi
18m
I 81
12.7 mi
15m
78th Division Highway
7.6 mi
8m
Lehigh Valley Thruway
6.5 mi
8m
MacArthur Road
4.6 mi
8m
Longest stretch:
Pennsylvania Turnpike
— 170.5 mi, about 3h 7m
Turn-by-Turn Driving Directions
Step-by-step road directions between Pittsburgh, PA and Cherryville, PA.
1
Start on Grant Street
45 ft·9 sec·Grant Street
2
Continue on Grant Street
0.3 mi·1 min·Grant Street
3
Take the ramp
0.4 mi·50 sec
Toward I 376 East: Monroeville
4
Merge onto I 376; US 22; US 30
14 mi·18 min·Penn-Lincoln Parkway East
Use the straight / slight right lanes.
5
Take the exit
0.2 mi·1 min
Exit 85Toward I 76, PATP: Ohio, Harrisburg
6
Continue on this road
0.2 mi·30 sec·this road
Use the straight lane.
7
Keep slight right at fork
0.2 mi·29 sec
Toward I 76 East: HarrisburgUse the slight right lane.
8
Merge onto I 76; PATP
170 mi·3 hr 7 min·Pennsylvania Turnpike
9
Take the exit
0.9 mi·2 min
Toward I 81, US 11: Carlisle, HarrisburgUse the slight right lane.
10
Keep slight left at fork
0.3 mi·54 sec
Toward US 11 North: HarrisburgUse the straight / slight right lanes.
11
Continue on US 11
1.1 mi·2 min·Harrisburg Pike
Use the straight lane.
12
Take the exit
0.3 mi·34 sec
Toward I 81 North: Harrisburg
13
Merge onto I 81
13 mi·15 min·I 81
Use the straight / right lanes.
14
Take the exit
0.2 mi·14 sec
Toward US 11, US 15: Enola, Marysville
15
Keep slight left at fork
0.3 mi·28 sec
Toward US 11 North, US 15 North: Marysville
16
Keep slight left at fork
0.4 mi·32 sec
17
Merge onto I 81
0.7 mi·1 min·George N. Wade Memorial Bridge
Use the straight / slight right lanes.
18
Continue on I 81
3.4 mi·4 min·American Legion Memorial Highway
19
Keep slight left at fork onto I 81
19 mi·22 min·American Legion Memorial Highway
Use the straight / slight right lanes.
20
Take the exit
0.7 mi·45 sec
Exit 89Toward I 78 East: Allentown
21
Continue on I 78
7.6 mi·8 min·78th Division Highway
22
Continue on I 78; US 22
43 mi·50 min·William Penn Highway
Use the straight lane.
23
Keep slight right at fork onto US 22
6.5 mi·8 min·Lehigh Valley Thruway
Exit 51Toward US 22 East: Pennsylvania Turnpike, LVI AirportUse the slight right lane.
24
Take the exit
0.2 mi·39 sec
Toward PA 145: MacArthur Road, 7th StreetUse the slight right lane.
25
Keep slight left at fork
166 ft·7 sec
Toward PA 145 North: WhitehallUse the left lane.
26
Turn left onto PA 145
4.6 mi·8 min·MacArthur Road
Use the straight lane.
27
Continue on PA 145
4.0 mi·6 min·Macarthur Road
28
Take the exit
489 ft·22 sec
29
Turn straight onto Blue Mountain Drive
1.8 mi·4 min·Blue Mountain Drive
30
Turn right onto PA 248
36 ft·0 sec·Lehigh Drive
31
Arrive at destination
PA 248
Trip Plan
To make the most of this 5-hour, 50-minute drive, consider an early morning departure from Pittsburgh to avoid potential rush hour traffic. With a longest stretch of 170.5 miles on the Pennsylvania Turnpike, plan your one recommended stop strategically about halfway through to stretch your legs and refuel. The estimated fuel cost of $49 is helpful for budgeting, but always check current prices. Since this is a single-day trip, you have flexibility, but breaking it up with a stop will enhance comfort.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 146.5 miles from Pittsburgh, PA, or about 2h 47m into the drive.
The longest continuous stretch on this route runs about 170.5 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 64 miles or 1h 17m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 146.5 miles or 2h 47m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 39m
Traffic, exits, and arrival timing usually matter more near Cherryville, PA than in the middle of the route.
Before You Leave
+
Open the route before leaving Pittsburgh, PA so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Pittsburgh, PA
This is one driving day of about 293.1 miles and 5h 50m.
Your first comfortable stop window is around 64 miles from Pittsburgh, PA.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Pennsylvania Turnpike for about 170.5 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 146.5 mi from Pittsburgh, PA
· 2h 47m into the drive
The midpoint is around 146.5 miles from Pittsburgh, PA, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel check
Top up before Pennsylvania Turnpike if your tank is already low. That segment runs about 170.5 miles.
Arriving in Cherryville, PA
The final approach into Cherryville, PA usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Cherryville, PA.
After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
National Parks Near This Route
Worth a detour if your schedule allows.
Carlisle Federal Indian Boarding School National Monument
National Monument
More than 7,800 children from 140 Tribes went to the Carlisle School from 1879 to 1918. The National Park Service will collaborate with families, affiliated Tribal Nations, the US Army, historians, an...
2 mi from route
~6 min detour
Free
near mile 181.9
The Appalachian Trail is a 2,190+ mile long public footpath that traverses the scenic, wooded, pastoral, wild, and culturally resonant lands of the Appalachian Mountains. Conceived in 1921, built by p...
4 mi from route
~10 min detour
Free
near mile 232.5
On Tuesday morning, September 11, 2001, the U.S. came under attack when four commercial airliners were hijacked and used to strike targets on the ground. Nearly 3,000 people tragically lost their live...
7 mi from route
~17 min detour
Free
near mile 80.9
The battle at Fort Necessity in the summer of 1754 was the opening action of the French and Indian War. This war was a clash of British, French and American Indian cultures. It ended with the removal...
24 mi from route
~61 min detour
Free
near mile 50.5
The South Fork Dam failed on Friday, May 31, 1889, and unleashed 20,000,000 tons of water that devastated Johnstown, PA. The flood killed 2,209 people but it brought the nation and the world together...
24 mi from route
~60 min detour
Free
near mile 101.1
Park data from the National Park Service API. Alerts update every 2 hours.
Fuel & Cost
Regular Gas
$48.59 one way
$97.18 round trip
$4.21/gal25.4 MPG avg103 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.61
$53.22
$106.44
premium
$4.93
$56.84
$113.69
diesel
$5.61
$64.71
$129.43
Estimated Tolls: $22.61
Pennsylvania Turnpike
(170.5 mi)$22.16
Lehigh Valley Thruway
(6.5 mi)$0.45
Toll estimates based on average 2024-2025 rates. EZ-Pass/SunPass discounts may lower the actual cost.
Estimated Trip Cost (one way, 1 person)
Fuel
$49
Tolls
$23
Meals
$25–$50
Total
$96–$121
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 102.6 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $31 in charging
· 1 stop
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
87.9
1
$30.78
$14.07
Efficient EV
73.3
0
$25.65
$11.72
EV Truck/SUV
117.2
1
$41.03
$18.76
Gas CO2
103 kg
EV CO2
34 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Pittsburgh, PA
Night
in Pittsburgh on Thursday
Local time
9:55 PM
EDT
Current temp
49°F
Unavailable
Live forecast
Destination
Cherryville, PA
Night
in Cherryville on Thursday
Local time
9:55 PM
EDT
Current temp
43°F
Unavailable
Live forecast
48°F
Hancock, MD
147 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
6 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
5h 50m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Pittsburgh, PA to Cherryville, PA covers 293.1 miles and takes about 5h 50m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are Pennsylvania Turnpike, William Penn Highway, American Legion Memorial Highway. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 146.5 miles from Pittsburgh, PA. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $48.59 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 23 significant decision points across 293.1 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 14.7 miles: Highway fork - watch signs carefully. Lane positioning matters here; at 185.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 186.2 miles: Highway fork - watch signs carefully. Lane positioning matters here.
Between Pittsburgh, PA and Cherryville, PA, road signs point toward Harrisburg, Marysville and Lvi Airport.
Yes. Nearby national parks include Carlisle Federal Indian Boarding School National Monument, Appalachian National Scenic Trail and Flight 93 National Memorial. There are 5 parks within detour distance of this route.
